Icahn School of Medicine at Mount Sinai
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NIH Training Grant in Systems and Developmental Biology and Birth Defects

NIH Training Grant in Systems and Developmental Biology and Birth Defects


Ethylin Jabs, MD


Robert Krauss, PhD


Eric Sobie, PhD


Department of Genetics and Genomic Sciences

Department of Developmental and Regenerative Biology

Pharmacology and Systems Therapeutics

Contact Us


Erin Brittain
Send e-mail
Tel: 212-241-7056
One Gustave L. Levy Place
Box 1497
New York , NY 10029

Program Overview

Systems biology is a relatively new discipline used to understand the complex interactions underlying healthy and diseased states of a cell, tissue, or organism. This requires knowledge of networks of processes and molecular and protein interactions. Studies of normal development and birth defects are more established classical disciplines. However to date, there has been very little integration of system biologic approaches to the study of development and inborn errors of development. Scientists who are versed in both mathematics and biology are needed to address the complexities of developmental biology. Thus, to fill the void of scientists trained in these multiple disciplines, Mount Sinai has received funding from the NIH for this integrated PhD predoctoral training program, Interdisciplinary Training in Systems and Developmental Biology and Birth Defects.  Mount Sinai has the commitment and infrastructure to administer this successful and rigorous educational program for predoctoral trainees.

Program Design

The overall organization includes at least 28 faculty from 12 different departments, institutes, and centers as well as 3 multidisciplinary training areas  (Genetics and Genomics Sciences; Developmental and Regenerative Biology; and Systems Biology of Disease and Therapeutics) and the Graduate School of Biological Sciences. An outstanding group of scientists and educators with expertise in systems biology, developmental biology or birth defects, are the faculty for the program. The Director is Ethylin Wang Jabs of the Department of Genetics and Genomics, and co-Directors, Eric Sobie of Pharmacology and Systems Therapeutics and Robert Krauss of Developmental and Regenerative Biology. The Curriculum will emphasize the integration of concepts of developmental biology, inborn errors of development, genomics, molecular biology, biochemistry, physiology, pharmacology; and quantitative reasoning, computational biology, and bioinformatics. In addition, journal clubs, and seminar series integrating systems biology, developmental biology and birth defects enhance the unique learning experience.

Training Faculty

Application Process and Requirements

The application form for PhD or MD/PhD predoctoral students for this training program can be found [here]. Funding preference is given to 3rd and 4th year students who have selected research projects appropriate for the goals of this training program.

Current Trainees

Jeffrey Bernitz Milo Smith Katherine Dauber Andrew Browne


Past Trainees

Betty Chang Timothy Cashman Raymond Liang  Arven Saunders