Annetine C Gelijns, PhD, JD
- PROFESSOR AND SYSTEM CHAIR | Population Health Science and Policy
Multi-Disciplinary Training AreaClinical Research Education Program [CLR]
LLM, Universities of Leyden Law School and Utrecht Department of Health Administration, School of Medicine
PhD, University of Amsterdam School of Medicine and Department of Science Policy
Investigator Award in Health Policy Research
International Fellow, Council on Health Care Technology
The Querido-Award for the most promising young investigator in public health, the National Foundation for Health Promotion and Disease Prevention (Praeventiefonds)
- Neuroprotection in Patients Undergoing Aortic Valve Replacement
All patients undergoing cardiac surgery, including AVR, face a risk for injury to the brain including stroke. Debris, such as plaque, may be dislodged from the wall of the aorta (the blood vessel leading from the heart to the brain and the rest of the body) during surgery...
- LVAD Therapy: Exploring the Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function
The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe and effective in improving heart function. MPCs are normally present in human bo...
- Management Practices and the Risk of Infection Following Cardiac Surgery
The purpose of the study is to determine the best ways to prevent infections after heart surgery. Participation in the study will last at most 3 months after heart surgery. The study will only collect information about the care patients receive during their planned surgery, an...
- Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients
The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe. In addition, this research is being done to test whether injecting the MPCs int...
- Surgical Ablation vs No Surgical Ablation for Patients with Persistent or Longstanding Persistent Atrial Fibrillation Undergoing Mitral Valve Surgery
The purpose of the research is to determine whether treating atrial fibrillation with surgical ablation during scheduled mitral valve surgery is better than mitral valve surgery by its...
- The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,
The purpose of this prospective cohort study is to characterize the specific sites and timing of clotting cascade activation triggered by CPB (cardiopulmonary bypass) and VAD (Ventricular Assist Device) therapy in end-stage heart failure patients. To control for the effect of ...
- Rate Control versus Rhythm Control for Postoperative Atrial Fibrillation
The purpose of the research is to compare two strategies for treating atrial fibrillation or atrial flutter, both of which are referred to as AF, after cardiac surgery. AF is the most common complication after cardiac surgery. AF is when the upper chambers of the heart (...
- Cardiothoracic Surgical Trials Network
The goal of the Cardiothoracic Surgical Trials Network (CTSN) is to foster a culture of rigorous scientific comparisons and to promote the evaluation of newer surgical techniques, devices, and innovative pharmaceutical and bioengineered products directed at improving cardiovas...
Gelijns A, Gabriel S. Looking beyond Translation — Integrating Clinical Research with Medical Practice. New England Journal of Medicine 2012 May 3; 366(18): 1659-66.
Gardner T, Miller M, O'Gara P, Gelijns A. Building an infrastructure for clinical trials in cardiac surgery. J Thorac Cardiovasc Surg 2011 Aug; 142(2): 265-6.
Gillinov A, Argenziano M, Blackstone E, Iribarne A, DeRose J, Ailawadi G, Russo M, Ascheim D, Parides M, Rodriguez E, Bouchard D, Taddei-Peters W, Geller N, Acker M, Gelijns A. Designing comparative effectiveness trials of surgical ablation for atrial fibrillation: experience of the Cardiothoracic Surgical Trials Network. J Thorac Cardiovasc Surg 2011 Aug; 142(2): 257-64.
Greco G, Egorova N, Gelijns A, Moskowitz A, Manganaro A, Zwolak R, Riles T, Kent K. Development of a novel scoring tool for the identification of large ≥5 cm abdominal aortic aneurysms. Ann Surg 2012 Oct; 252(4): 675-82.
Egorova N, Gelijns A, Moskowitz A, Emond J, Krapf R, Lazar E, Guillerme S, Kaplan H, Greco G. Process of care events in transplantation: effects on the cost of hospitalization. Am J Transplant 2010 Oct; 10(10): 2341-8.
Gelijns A, Ascheim D, Parides M, Kent K, Moskowitz A. Randomized trials in surgery. Surgery 2009 Jun; 145(6): 581-7.
Ascheim D, Gelijns A, Rose E. Innovation with experience using implantable left ventricular assist devices. Circ Heart Fail 2009 Jan; 2(1): 1-2.
Iribarne A, Russo M, Moskowitz A, Ascheim D, Brown L, Gelijns A. Assessing technological change in cardiothoracic surgery. Semin Thorac Cardiovasc Surg 2009 Spring; 21(1): 28-34.
Russo M, Gelijns A, Stevenson L, Sampat B, Aaronson K, Renlund D, Ascheim D, Hong K, Oz M, Moskowitz A, Rose E, Miller L. The Cost of Medical Management in Advanced Heart Failure during the Final Two Years of Life. Rematch Investigators. J Heart Failure 2008 Oct; 14 (8): 651-658.
Egorova N, Moskowitz A, Gelijns A, Weinberg A, Curty J, Rabin-Fastman B, Kaplan H, Cooper M, Fowler D, Emond J, Greco G. Managing the prevention of retained surgical instruments: what is the value of counting? . Annals of Surgery 2008; 247: 13-18.
Neaton J, Normand S, Gelijns A, Starling R, Mann D, Konstam M. Designs for mechanical circulatory support device studies. Journal of Cardiac Failure 2007 Feb; 13(1): 63-74.
Parides M, Moskowitz A, Ascheim D, Rose E, Gelijns A. Progress versus precision: challenges in clinical trial design for left ventricular assist devices. Annals of Thoracic Surgery 2006 Sep; 82(3): 1140-6.
Gelijns A, Thier S. Medical Innovation and Institutional Interdependence; Rethinking University-Industry Connections. . JAMA 2002 January; 287: 72-77.
Rose E, Gelijns A, Moskowitz A. Long Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure. The New England Journal of Medicine 2001; 345: 1435-1443.
Gelijns A, Rosenberg N, Moskowitz A. Capturing the Unexpected Benefits of Medical Research. New Engl J Med 1998; 339: 693-8.