Dean’s CoREs

Dean's CoREs bring state-of-the-art, crucial instrumentation and methodologies for modern biomedical research within reach of all Icahn School of Medicine at Mount Sinai investigators, post docs, and graduate students. Our facilities are staffed by experts who not only provide research services, but are also sources of instruction and training. As such, our CoREs constitute a major educational resource for those wishing to diversify or explore new avenues of research. CoREs are administered through the Office of the Dean and partially subsidized by institutional funds. Should you wish to establish a new Dean’s CoREs, you may submit a proposal that involves users from multiple departments and disciplines for review by the Dean’s Office.

General Guidelines

  • CoREs are open to all faculty, with equal access regardless of departmental or center affiliation; priority is given to Icahn School of Medicine at Mount Sinai faculty over external users.
  • The CoREs utilize the iLab Platform (core managemnt software) to reserve equipment, request services, and billing.
  • All users must register for an iLab account using the link: https://ismms.corefacilities.org/account/login 
  • Use of CoRE services requires authorization from a Principal Investigator, for billing purposes. 
  • Billing is inititiated when service is requested. 
  • Users are invoiced and billed by fund number on a monthly basis.
  • Users who cancel appointments less than 24 hours in advance are subject to full charge.
  • Direct questions regarding monthly billing should be directed to CoRE Directors.
  • The CoREs are not responsible for the application of their products or outcome of research studies involving their products.
  • Each CoRE has an advisory committee that meets semi-annually with the CoRE directors. 

Accessing Stony Brook University Cores:

The CoRE administration is pleased to announce the formal agreement for Stony Brook University (SBU) to provide access to the SBU cores including the Proteomics and Metabolomics facilities to the Icahn School of Medicine at Mount Sinai (ISMMS). This agreement was presented at the recent SBU / ISMMS Scientific Symposium on October 30, 2017.

At the end of November all SBU cores, including Proteomics and Metabolomics, became available to ISMMS researchers. For more information on the services provided by SBU cores, please visit Stony Brook University's Research Core Facilities. For more information on the expertise in discovery and quantitative proteomics, metabolomics, and lipidomics provided by SBU, please visit visit their Biological Mass Spectrometry Shared Resource facility.

To access SBU cores, please follow these steps:

  1. Log into iLab
  2. Click on the “list all cores” link on the left-hand menu
  3. Select other institutions in the dropdown menu and search for Stony Brook
  4. Select the core you want to use

If you have any questions about SBU cores, please email Shekhar Patil

 

Accessing Simons Electron Microscopy Center:

Icahn School of Medicine at Mount Sinai is a member of the New York Structural Biology Center (NYSBC) Consortium. NYSBC provides unparalleled expertise and instrumentation including high throughput gene-to­-structure determination, structure-based drug design, crystallography, NMR spectroscopy, cryo-electron microscopy and protein production. Housed at its Manhattan facility is the Simons Electron Microscopy Center (SEMC) that provides high-end transmission electron microscopes (TEMs), direct detection cameras, and computational support for single particle analysis.

Under the affiliation, ISMMS researchers have access to both the instrumentation and staff resources of the cryo-EM facility at the SEMC and include:

  • Advanced instrumentation and expertise for electron microscopy
  • Training in instrumentation and techniques, including accredited classes and individual instruction
  • Assigned, dedicated instrument time is part of consortium membership - There are no special fees beyond annual membership dues paid by the school.

 

Getting Access to SEMC cryo-TEM

  1. Create an Account 
    Create a SEMC account for yourself with the following form: SEMC Account Registration for yourself. Note: You must create an account from a member institution IP address. Once created you may then log in from anywhere.
  1. Register Your Project 
    Register your project by using your SEMC credentials using the following form: EM Proposal Submission
  1. Review SEMC Information 
    Read the resources and capabilities of the Simons Electron Microscopy Center on this site: Considerations before beginning a project and Overview of EM Techniques.
  1. Schedule A Meeting 
    Arrange a meeting with the SEMC staff (EMG@NYSBC.org) and notify your institution’s Operations Committee Member

 If you have any questions about SEMC, please email Shekhar Patil, PhD.

 

Administration, Dean’s CoREs

Meet the team that manages all administrative aspects of of our Dean’s CoREs at the Icahn School of Medicine at Mount Sinai.

Reginald W. Miller, DVM, DACLAM
Dean for Research Operations and Infrastructure

Shekhar Patil, PhD, Administrative Director

Veronica Moses, CM, Financial Director

Viviana Badillo, Financial Analyst

 CoREs

Directors

Flow Cytometry

Jordi Ochando, PhD 

Freezer Farm

Michael Donovan, MD, PhD

Biorepository and Pathology 

Rachel Brody, MD PhD

Irradiator

Kevin Kelley, PhD

Microscopy

Deanna Benson, PhD

Mouse Genetics

Kevin Kelley, PhD

Quantitative PCR

Venugopalan Nair, PhD

Rodent Breeder Colony Management  

Jonathan Cohen, DVM

Neuropathology Brain Bank and Research

John F. Crary, MD, PhD

Main iLab Link

Biorepository and Pathology iLab Reservation

Flow Cytometry iLab Reservation

Microscopy iLab Reservation

Transgenic iLab Reservation

qPCR iLab Reservation

It is important that you acknowledge all the Dean's CoREs and CoREs in all publications that include data derived from the facility. This is a National Institutes of Health requirement.