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Denise Nassisi

  • ASSOCIATE PROFESSOR Emergency Medicine
  • ASSOCIATE PROFESSOR Medicine, General Internal Medicine
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  • American Board of Emergency Medicine

  • American Board of Internal Medicine


  • MD, S.U.N.Y. at Stony Brook Sch. of Med

  • Residency, Internal Medicine
    Bronx Municipal Hospital Center

  • Residency, Internal Medicine
    Mount Sinai Hospital


    Denise Nassisi, MD, FACEP is an Associate Professor in the Departments of Medicine and Emergency Medicine at Mount Sinai. She is currently the Associate Director of the Emergency Department (ED) at Mount Sinai, serving as the Director of ED Performance Improvement, as well as Director of the Geriatric ED and the Clinical Trials Director. Dr. Nassisi received a B.S. in biochemistry from Binghamton University and received her M.D. from SUNY Stony Brook where she was inducted into the Alpha Omega Alpha Honor Society. She trained at Jacobi Hospital and Mount Sinai Hospital and is board-certified in both Emergency Medicine and Internal Medicine. She was granted Fellowship in Mount Sinai’s Institute for Medical Education, served on the Mount Sinai School of Medicine CME committee, and has contributed to the National Board of Medical Examiners United States Medical Licensing Exam. She has precepted many students and residents in the ED and developed evidence-based clinical guidelines. She has served for many years on the Mount Sinai IRB, served as reviewer for the Empire Clinical Research Investigator Program, and has successfully completed numerous industry-sponsored clinical trials. Currently she is an investigator on the CMMS Innovations Grant: GEDI WISE Geriatric emergency department innovations in care through workforce, informatics, and structural enhancements.

    Regional / National Committees / Advisory Boards:


    NY ACEP Research Committee

    NY County Elder Fatality Review Team



Pallin D, Nassisi D. Skin and Soft Tissue Infections. In: Emergency Medicine: Concepts and Clinical Practice, 8th Edition. Elsevier; pp1851-1863.

Nassisi D, Oishi M. Evidence-based Guidelines for Empiric Antimicrobial Therapy in the Emergency Department. Emergency Medicine Practice 2012 January; 14(1).

Nassisi D. ED Infections in the Era of CA -MRSA. Emergency Medicine Practice 2010 October; 12(10).

Nassisi D. The Confused Patient: Ten Most Common Causes and Critical Actions. In: Emergency Medicine Oral Board Review. Cambridge University Press;.

Nassisi D, Jagoda A. Delirium. In: Evidence Based Emergency Medicine. Blackwell Publishing;.

Nassisi D, Okuda Y. ED Management of Delirium and Agitation. Emergency Medicine Practice 2007 January; 9(1).

Nassisi D, Korc B, Hahn S, Bruns J Jr, Jagoda A. The Evaluation and Management of the Acutely Agitated Elderly Patient. The Mount Sinai Journal of Medicine 2006; 73: 976-984.

Christie J, Nassisi D, Wilets I, DuHamel K, Winkel G, Hilliard R, Jandorf L. Colorectal Cancer Screening in an ED Population. Journal of the National Medical Association 2006 July; 98(7).

Kou V, Nassisi D. Unstable Angina and Non-Q Wave Myocardial Infarction. The Mount Sinai Journal of Medicine 2006 January; 73(1).

Wilets I, O'Rourke M, Nassisi D. How Patients and Visitors to an Urban Emergency Department View Clinical Research. Academic Emergency Medicine 2003 October; 10(10): 1081-1085.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Nassisi did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Insurance Information

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

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One Gustave L. Levy Place
Box 1620
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Tel: 212-824-8084
Fax: 212-426-1946