Erik Langhoff, MD, PhD
- DEAN FOR BRONX VETERANS ADMINISTRATION AFFAIRS
- PROFESSOR | Medicine
BA, Soro Academy
MD, University of Copenhagen, Faculty of Medicine
PhD, University of Copenhagen, Faculty of Medicine
Massachusetts General Hospital
Treatment of Chronic Renal Failure
The Bronx VA is participating in a research study to explore the beneficial effect of lowering homocysteine levels in patients with chronic renal failure. Chronic renal failure is associated with elevated levels of homocysteine which can be significantly reduced by treatment with folate, B6, and B12. It is thought that elevated levels of homocysteine may lead to vascular events that cause increase risk of arterial thrombosis, coronary disease of cerebrovascular events. This study will follow these clinical endpoints. Dr. Langhoff's basic research interests are HIV-1, Cytomegalovirus, and Polyoma Virus.
Pinkus GS, Pinkus JL, Langhoff E, Matsumura F, Yamashiro-Matsumura S, Mosialos G, Said JW. Faccin: A sensitive new marker for Reed-Sternberg Cells of Hodgkin's Disease-Evidence for a dendritic B cell derivation?. Am J Pathology 1997; 150: 543-562.
Ahsan N, Holman MJ, Riley TR, Langhoff E, Yang HC. Peliosis hepatis due to Bartonella heuselae in transplantaion - a hemato-hepato-renal syndrome. Transplantation 1998; 65(7): 1000-1003.
Sonderbye L, Feng S, Yacoubian S, Buehler H, Ahsan N, Mulligan R, Langhoff E. In vivo and in vitro modulation of immune stimulatory capacity of primary dendritic cells by adenovirus mediated gene transduction. Exp Clin Immunogen 1998; 15: 100-111.
Ahsan N, Langhoff E. Immunopathogenesis of HIV. Seminars Nephrology 1998; 17(4): 422-435.
Ahsan N, Holman MJ, Langhoff E, Yang HC. Oral ganciclovir in the prevention of cytomegalocity infection in post-kidney transplant 'CMV at risk' recipients. Transplant Proc 1998; 30: 1383-1385.
Jaffe R, DeVaughn D, Langhoff E. Fascin and the differential diagnosis of childhood histiocytic lesions. Pediatr Dev Pathol 1998; 1: 216-221.
Sonderbye L, Mehan S, Paulson R, Ahsan N, Ladefoged Y, Langhoff E. Immunohistochemical study of actin binding protein (p55) in the human kidney. Transplantation 1998; 65(7): 1004-1008.
Yang HC, Holman MJ, Langhoff E, Ulsh PJ, Dellock CA, Gupta M, Ahsan N. Tacrolimus/low-dose mycophenolate mofetil versus microemulsion cyclosporine/low-dose mycophenolate mofetil after kidney transplantation--1-year follow-up of a prospective, randomized clinical trial. Transplant Proc 1999 Feb-Mar ; 31(1-2): 1121-4.
Tolkoff-Rubin N, Langhoff E. Renal Complications of Organ Transplantation. In: Ginns LG, Cosimi AB, Morris PJ, editors. Transplantation. Boston, MA, Blackwell Science; 2000. pp725-745.
Bennekov T, Spector D, Langhoff E. Induction of Immunity Against Human Cytomegalovirus. Mt Sinai J Med 2004; 71: 86-93.