Julie M Blander, PhD
- ASSOCIATE PROFESSOR | Medicine, Clinical Immunology
- ASSOCIATE PROFESSOR | Microbiology
Research Topics:Antigen Presentation, Apoptosis/Cell Death, Autoimmunity, Cell Biology, Cellular Differentiation, Cellular Immunity, Dendritic Cells, Gene Discovery, Immunological Tolerance, Immunology, Infectious Disease, Knockout Mice, Lymphocytes, Lysosomes/endosome, Macrophage, Microarray, Signal Transduction, T Cells, Tolerance, Transgenic Mice, Vaccine Development
Multi-Disciplinary Training AreaImmunology [IMM]
BS, American University of Beirut
University of California
PhD, University of Pittsburgh School of Medicine
Yale University School of Medicine
Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease
MSSM Faculty Council 'Junior Faculty Award for Academic Excellence'
Harold and Golden Lamport Award
Hirschl Scholar Award
J.V. Satterfield Award
Specific Clinical/Research Interest: Innate immunity, apoptosis, inflammation and the control of adaptive immunity.
Current Students: Priyanka Nair, PhD student and Andrew Kent, MD/PhD graduate student.
Postdoctoral Fellows: Gaetan Barbet, Ph.D., Laura Campisi, Ph.D., Diego Mourao-Sa, Ph.D., Soumit Roy, Ph.D., Julien Moretti, Ph.D, Nicolas Vabret, Ph.D.
Research Coordinator: Cheri Korb.
Julie Magarian Blander, PhD, is the Director of the Innate Immunity Research Program. The laboratory focuses on elucidating the innate immune mechanisms controlling inflammation, host defense and adaptive immunity.
1. Garaude, J, Kent, A, van Rooijen, N, and Blander, JM, Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. Science translational medicine, 2012. 4(120): p. 120ra116. [Abstract] [Reprint] [Full text]
2. Puga, I, Cols, M, Barra, CM, He, B, Cassis, L, Gentile, M, Comerma, L, Chorny, A, Shan, M, Xu, W, Magri, G, Knowles, DM, Tam, W, Chiu, A, Bussel, JB, Serrano, S, Lorente, JA, Bellosillo, B, Lloreta, J, Juanpere, N, Alameda, F, Baro, T, de Heredia, CD, Toran, N, Catala, A, Torrebadell, M, Fortuny, C, Cusi, V, Carreras, C, Diaz, GA, Blander, JM, Farber, CM, Silvestri, G, Cunningham-Rundles, C, Calvillo, M, Dufour, C, Notarangelo, LD, Lougaris, V, Plebani, A, Casanova, JL, Ganal, SC, Diefenbach, A, Arostegui, JI, Juan, M, Yague, J, Mahlaoui, N, Donadieu, J, Chen, K, and Cerutti, A, B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nature immunology, 2012. 13(2): p. 170-180. [Abstract]
3. Nair, P, Amsen, D, and Blander, JM, Co-ordination of incoming and outgoing traffic in antigen-presenting cells by pattern recognition receptors and T cells. Traffic, 2011. 12(12): p. 1669-1676. [Abstract]
4. Sander, LE, Davis, MJ, Boekschoten, MV, Amsen, D, Dascher, CC, Ryffel, B, Swanson, JA, Muller, M, and Blander, JM, Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature, 2011. 474(7351): p. 385-389. [Abstract]
5. Brereton, CF and Blander, JM, The unexpected link between infection-induced apoptosis and a TH17 immune response. Journal of leukocyte biology, 2011. 89(4): p. 565-576. [Abstract]
6. Garaude, J and Blander, JM, ICOStomizing immunotherapies with T(H)17. Science translational medicine, 2010. 2(55): p. 55ps52. [Abstract]
7. Brereton, CF and Blander, JM, Responding to infection and apoptosis--a task fo