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Madhu Mazumdar

  • SENIOR FACULTY Population Health Science and Policy
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Education

  • MA, University of Delhi
    Statistics

  • MS, University of Pittsburgh
    Mathematics

  • PhD, Penn State University
    Mathematical Statistics

  • Fellowship, Drexel University
    Executive Leadership in Academic Medicine

Biography

    Dr. Mazumdar’s primary focus is on the design and analysis of clinical trials, observational studies, and meta-analyses. She has designed and analyzed research studies based on prospectively collected data, retrospective chart reviews, and claims-based administrative data; further and has extensive experience in development and implementation of novel methodologies.

Awards

  • 2013 - 2013
    Fellow
    American Statistical Association

Research

Training, Mentoring, and Related Tool development
Teaching experience includes leadership of both an introductory and advanced course in statistical methods for residents, fellows, and junior faculty members pursuing the MS in Clinical Investigation (NIH awarded K-30 Program) and for students pursuing a doctorate in Immunology, Pharmacology, and Computational Biomedicine. Dr. Mazumdar has also taught special topics in biostatistics at WCMC for the Fellowship in Health Care Quality and Medical Informatics Research, the Residency and Fellowship in Pathology, and the Training Program in Genetics and Pulmonary Medicine.

Her external teaching experience includes a weeklong “Clinical Trials Design Workshop” organized by the Radiological Society of North America, a weeklong ‘Clinical Research Training Institute Summer Workshop’ organized by the American Society of Hematology, and yearly lectures on special topics at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Statistical Research

Dr. Mazumdar’s statistical research is guided by clinical collaborations. Such studies resulted in approximately 20 papers, 6 funded grants, and 1 edited book section. I developed methodologies for the following: detection of publication bias in meta-analysis; adjustment for selection bias in clinical trials; allowance for interim looks at data in clinical trials comparing diagnostic tests; and estimation of misclassification rate of therapeutic responders when oncologic response criteria are changed.

Biostatistics and Epidemiology Program Development

Dr. Mazumdar was founding Chief of the Division of Biostatistics and Epidemiology (B&E) at Weill Cornell Medical College (WCMC). She effectively led the development, implementation and continued evolution of Research Design and Biostatistics Core of Clinical and Translational Science Center (CTSC, the WCMC CTSA) since initial funding and transformed the Biostatistics Core model from prior practices under the GCRC (General Clinical Research Center) umbrella.

Publications

Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088-1101.

Motzer RJ, Murphy BA, Bacik J, Schwartz LH, Nanus DM, Mariani T, Loehrer P, Wilding G, Fairclough DL, Cella D, Mazumdar M. Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000; 18: 2972-2980.

Mazumdar M, Liu A. Group Sequential Design for comparative diagnostic accuracy studies. Stat in Med 2003; 22: 727-739.

Mazumdar M, Smith A, Schwartz LH. A statistical simulation study finds discordance between WHO criteria and RECIST guideline. Journal of clinical epidemiology 2004; 57: 358-365.

Memtsoudis SG, Sun X, Chiu YL, Stundner O, Liu SS, Banerjee S, Mazumdar M, Sharrock NE. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients.. Anesthesiology 2013; 118: 1046-1058.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Mazumdar did not report having any of the following types of financial relationships with industry during 2013 and/or 2014: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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