Randall Owen

ASSOCIATE PROFESSOR Surgery

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randall.owen@mountsinai.org

Specialty

Surgery

Certifications

American Board of Surgery

Clinical Focus

Education

MD, Columbia University College of Physicians & Surgeons
MS, Albert Einstein College of Medicine, Clinical Research
Clinical Research
Residency, Surg.
Montefiore Medical Center
Fellowship, Head & Neck Surgery
Montefiore Medical Center

Biography

Dr. Owen's clinical and research interest center on Head & Neck and Endocrine Surgery. This includes a broad range of entities including thyroid nodules, goiters and cancer, hyperparathyroidism, mouth, throat, salivary gland and neck cancers and masses.

Consultation in the office is undertaken and includes a detailed interview and physical examination, along with possible sonogram, needle biopsy or fiberoptic laryngoscopy. Surgical procedures employed to cure these conditions include minimally invasive parathyroid surgery under local anesthesia, thyroid surgery performed through the axilla, and radical cancer resections with free flap reconstruction. Dr. Owen also performs basic general surgical procedures including cholecystectomy, appendectomy, incisional and inguinal hernia repair, portacath and gastrostomy placement. He recently published his groundbreaking work on radiofrequency ablation of head and neck cancers in the May 2011 issue of Archives of Otolaryngology/Head & Neck Surgery.

Dr. Owen received a B.A. with honors in science and humanities from Seattle Pacific University. He then obtained his M.D. degree from Columbia University College of Physicians and Surgeons. Subsequently, he completed a general surgery residency at Montefiore Medical Center/Albert Einstein College of Medicine. He then completed a Head & Neck surgery fellowship at Montefiore after which he joined the faculty. In 2006 he became the chief of the Head & Neck Division at Montefiore. In 2009 he was recruited to The Mount Sinai Medical Center to join the Metabolic, Endocrine & Minimally Invasive Surgery Division.

Dr. Owen has a strong interest in medical and other missions. He has overseen a re-housing effort in Haiti since the earthquake in January 2010. Previous mission trips have been to the Philippines, Kenya, Romania, Pakistan and Gabon. Dr. Owen is President of the New York City Council of the Christian Medical and Dental Associations.

Awards

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Surgical Education Award
2006 -
“Attending of the Year” Award
1999 -
Christian Medical and Dental Society Short-Term Mission Scholarship
1993 -
MAP-Reader's Digest International Fellowship Recipient

Research

Radiofrequency Ablation (RFA) of Head and Neck Cancer (HNC)

Dr. Owen carried out the first series of RFA on advanced HNC for patients with no other good treatment options. There were some excellent results such as relief of pain and shrinkage or destruction of tumor. There were also some complications which was expected given that this treatment is novel. Further study is needed to refine the techniques to make it an appropriate option for patients with advanced disease.

Parathyroid Surgery

Dr. Owen presented his series of nearly 400 parathyroid operations at the 2009 American Head and Neck Society annual meeting. He showed that measuring intraoperative PTH levels seven minutes after lesion excision allowed early determination of cure 80% of the time. 99% of patients were cured of their disease.

Publications

Beitler JJ, Garg M, Owen RP, Sarta C, Smith RV, Yaparpalvi R. High-dose-rate brachytherapy plus neck dissection for nodal disease. Head Neck. 2008; 30: 933-938.

Brook AL, Gold MM, Miller TS, Gold T, Owen RP, Sanchez LS, Farinhas JM, Shifteh K, Bello JA. CT-guided radiofrequency ablation in the palliative treatment of recurrent advanced head and neck malignancies. J Vasc Interv Radiol 2008; 19: 725-735.

Brook AL, Bello JA, Miller TS, Owen RP, Tang ER. Management of Malignant Extracranial Head and Neck Tumors. Image Guided Interventions 2008;.

Beitler JJ, Smith RV, Owen RP, Silver CE, Mazumdar M, Wadler S. Phase II clinical trial of parenteral hydroxyurea and hyper-fractionated, accelerated external beam radiation therapy in patients with advanced squamous cell carcinoma of the head and neck: toxicity and efficacy with continuous ribonucleoside reductase inhibition. Head Neck 2007; 29: 18-25.

Li W, Tonelli J, Kishore P, Owen R, Goodman E, Scherer PE, Hawkins M. Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle . Am J Physiol Endocrinol Metab. 2007; 292(E): 1301-1307.

Belbin TJ, Bergman A, Brandwein-Gensler M, Chen Q, Childs G, Garg M, Haigentz M, Hogue-Angeletti R, Moadel R, Negassa A, Owen R, Prystowsky MB, Schiff B, Schlecht NF, Shifteh K, Smith RV, Zheng X. Head and neck cancer: reduce and integrate for optimal outcome. Cytogenet Genome Res 2007; Res(118): 92-109.

Owen RP, Silver CE, Ravikumar TS, Brook A, Bello J, Breining D. Techniques for Radiofrequency Ablation of Head and Neck Tumors. Archives of Otolaryngology/Head & Neck Surgery. 2004; 130: 52-56.

Yang WL, Yang-Biggs G, Wu Y, Gallos G, Owen RP, Ravikumar TS. Development of Cross-Resistance Between Heat and Cisplatin or Hydroxyurea Treatments in FaDu Squamous Carcinoma Cells. Journal of Surgical Research 2003; 111: 143-151.

Owen RP, Ravikumar TS, Silver CE, Beitler J, Wadler S, Bello J. Radiofrequency Ablation of Head and Neck Tumors: Dramatic Results From Application of a New Technology. Head and Neck 2002; 24: 754-758.

Silver CE, Kim H, Stern WR, Owen RP. Bailey BJ, editor. Thyroid disease and surgery. Philadelphia, Lippincott, Williams and Wilkens;.

Owen RP, Khan SA, Negassa A. Radiofrequency Ablation of Head and Neck Cancer.. Arch Otolaryngol Head Neck Surg. 2001 May; 137(5): 493-8.

Ferlito A, Owen RP. Proposal for rational classificationof neck dissections. Head Neck 2011 March; 33(3): 445-450.

Owen RP, Chou KJ, Silver CE. Thyroid and parathyroid in pregnancy. Eur Arch Otorhinolaryngol 2010 December; 267(12): 1825-35.

Silver CE, Owen RP. Aggressive variants of papillary thyroid carcinoma. Head Neck 2011 July; 33(7): 1052-9.

Brandwein-Gensler M, Smith RV, Owen RP. Validation of histologic risk model in a new cohort of patients with head and neck squamous cell carcinoma. Am J Surg Pathol 2010 May; 34(5): 676-88.

Owen RP, Silver CE, Pellitteri PK. Parathyroid carcinoma. Head Neck 2011 March; 33(3): 429-36.

Genden EM, Ferlito A, Owen RP. Contemporary management of cancer in the oral cavity. Eur Arch Otorhinolaryngol 2010 July; 267(7): 1001-17.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Owen did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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