Stephen Scelsa, MD
- PROFESSOR | Neurology
Research Topic:Amyotrophic Lateral Sclerosis
I am a neurologist and neuromuscular specialist with expertise in Neuromuscular Diseases, Electromyography, Polyneuropathies, and Amyotrophic Lateral Sclerosis (ALS) clinical care and trials. I am the Director of the Neuromuscular Division at Beth Israel Medical Center since 1997. I am the co-founder and Director of the Beth Israel Medical Center/ALS Association NY Chapter ALS Center which was created in 1997. Since 2003, the center has gained national recognition for participation in ALS clinical trials. I have access to a large population of patients with Amyotrophic Lateral Sclerosis. We follow 130 patients at any given time. I am an active member of NEALS, the North Eastern ALS Consortium. I have a strong interest in conducting clinical trials in Neurology. At Beth Israel we conducted an investigator initiated phase1/2 trial of indinavir in ALS, in collaboration with Columbia University Medical Center. I was the principle investigator. Our center has also conducted a controlled study of reverse transcriptase detection in the serum and CSF of HIV negative, sporadic ALS patients. I received 4 NIH consortium grants for clinical trials in ALS patients. We have collaborated with Mass General and the Mayo Clinic as well. My experience and expertise in Amyotrophic Lateral Sclerosis research will allow me to contribute to the successful execution of clinical trials in this center. Our research goal is to find more effective disease modifying drugs to treat ALS.
I have a large practice experience with entrapment neuropathies, spine diseases of the nervous system, polyneuropathies, myasthenia gravis and ALS. I am well known nationally for my skills as an electromyographer. I also have expertise in stimulation single fiber EMG used in the diagnosis of myasthenia gravis.
I was a Professor of Clinical Neurology at Albert Einstein college of Medicine , Bronx, NY 2012-2014 and Professor of Neurology at the Icahn Scholl of Medicine at Mount Sinai since 1/1/2014. I have authored numerous scientific publications and the text book “Herskovitz, S., Scelsa S.N., Schaumburg H.H.: Peripheral Neuropathies in Clinical Practice. Oxford University Press, New York, Jan 2010.” I am a reviewer for Neurology, Neurology: Neuroimmunology & Neuroinflammation, and Muscle and Nerve journals. I have twice received the best teacher award for the Mount Sinai Beth Israel Neurology residency, and was nominated to Best Doctors in America several years since 2005
Neurology, American Board of Psychiatry and Neurology
- Amyotrophic Lateral Sclerosis
- Bell's Palsy
- Carpal Tunnel Syndrome
- Chronic Inflammatory Demyelinating Neuropathy
- Diabetic Neuropathy
- Electrodiagnostic Testing (EMG/NCS)
- Electromyography (EMG)
- Guillain-Barré Syndrome
- Lumbar Radiculopathy
- Myasthenia Gravis
- Nerve conduction study (NCS)
- Neuromuscular Disease
- Neuropsychological testing
- Peripheral Neuropathy
MD, S.U.N.Y., Health Science Center
Internship, Internal Medicine, Montefiore Medical Center
Residency, Neurology, Albert Einstein College of Medicine
Fellowship, Neuromuscular, Albert Einstein College of Medicine
Beth Israel Neurology Teaching Award
Beth Israel Neurology Teaching Award
M.D. conferred Cum Laude
B.S. conferred Summa Cum Laude
Chemistry Honor Society
Scelsa SN, Lipton RB, Sander H, Herskovitz S. Headache characteristics in hospitalized patients with Lyme disease. Headache 1995 Mar; 35(3).
Scelsa SN, Simpson DM, Reichler BD, Dai M. Extraocular muscle involvement in Becker muscular dystrophy. Neurology 1996 Feb; 46(2).
Berger AR, Herskovitz S, Scelsa S. The restoration of IVIg efficacy by plasma exchange in CIDP. Neurology 1995 Aug; 45(8).
Bronster DJ, Yonover P, Stein J, Scelsa SN, Miller CM, Sheiner PA. Demyelinating sensorimotor polyneuropathy after administration of FK506. Transplantation 1995 Apr; 59(7).
Scelsa SN, Herskovitz S, Berger AR. A predominantly motor polyradiculopathy of Lyme disease. Muscle & nerve 1996 Jun; 19(6).
Scelsa S, Frost M, Valderrama R, Revan S, Pipia P, DiPaola M. Prevention and treatment of experimental autoimmune myasthenia gravis with anti-rabbit thymocyte serum and gammaglobulin in rabbits. Pathobiology : journal of immunopathology, molecular and cellular biology 1995; 63(3).
Scelsa SN, Simpson DM, McQuistion HL, Fineman A, Ault K, Reichler B. Clozapine-induced myotoxicity in patients with chronic psychotic disorders. Neurology 1996 Dec; 47(6).
Scelsa SN. Ulnar-median and median-ulnar anastomoses in the forearm: a patient report. Electromyography and clinical neurophysiology; 40(5).
Scelsa SN. Syringomyelia presenting as ulnar neuropathy at the elbow. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2000 Sep; 111(9).
Sander HW, Scelsa SN, Conigliari MF, Chokroverty S. The short exercise test is normal in proximal myotonic myopathy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2000 Feb; 111(2).
Reichler BD, Scelsa SN, Simpson DM. Hereditary neuropathy and vocal cord paralysis in a man with childhood diphtheria. Muscle & nerve 2000 Jan; 23(1).
Scelsa SN, Herskovitz S, Bieri P, Berger AR. Median mixed and sensory nerve conduction studies in carpal tunnel syndrome. Electroencephalography and clinical neurophysiology 1998 Jun; 109(3).
Scelsa SN, Herskovitz S, Reichler B. Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia. Muscle & nerve 1998 Nov; 21(11).
Scelsa SN, Herskovitz S. Miller Fisher syndrome: axonal, demyelinating or both?. Electromyography and clinical neurophysiology 2000 Dec; 40(8).
Scelsa SN, Khan I. Blood pressure elevations in riluzole-treated patients with amyotrophic lateral sclerosis. European neurology 2000; 43(4).
MacGowan DJ, Scelsa SN, Imperato TE, Liu KN, Baron P, Polsky B. A controlled study of reverse transcriptase in serum and CSF of HIV-negative patients with ALS. Neurology 2007 May; 68(22).
Herskovitz S, Song H, Cozien D, Scelsa SN. Sensory symptoms in acquired neuromyotonia. Neurology 2005 Oct; 65(8).
Scelsa SN, MacGowan DJ, Mitsumoto H, Imperato T, LeValley AJ, Liu MH, DelBene M, Kim MY. A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS. Neurology 2005 Apr; 64(7).
Scelsa SN, Ghali V, Herskovitz S, Bieri P, Shank DL, MacGowan DD, Liau S. Blood gammadelta T cells, Campylobacter jejuni, and GM1 titers in Guillain-Barré syndrome. Muscle & nerve 2004 Oct; 30(4).
Scelsa SN, Yakubov B, Salzman SH. Dyspnea-fasciculation syndrome: early respiratory failure in ALS with minimal motor signs. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2002 Dec; 3(4).
MacGowan DJ, Scelsa SN, Waldron M. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 2001 Sep; 57(6).
Gwinn K, Corriveau RA, Mitsumoto H, Bednarz K, Brown RH, Cudkowicz M, Gordon PH, Hardy J, Kasarskis EJ, Kaufmann P, Miller R, Sorenson E, Tandan R, Traynor BJ, Nash J, Sherman A, Mailman MD, Ostell J, Bruijn L, Cwik V, Rich SS, Singleton A, Refolo L, Andrews J, Zhang R, Conwit R, Keller MA. Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. PloS one 2007; 2(12).
Scelsa SN, Berger AR, Herskovitz S. Electrophysiologic correlates of weakness in L5/S1 radiculopathy. Electromyography and clinical neurophysiology; 41(3).
Hussain A, Scelsa SN. Sensory neuronopathy with Ro antibodies: response to combination immunosuppression. Journal of clinical neuromuscular disease 2010 Mar; 11(3).
Scelsa SN. Familial, demyelinating sensory and motor polyneuropathy with conduction block. Muscle & nerve 2010 Apr; 41(4).
Karam C, Scelsa SN, Macgowan DJ. The clinical course of progressive bulbar palsy. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2010 Aug; 11(4).
Kaufmann P, Thompson JL, Levy G, Buchsbaum R, Shefner J, Krivickas LS, Katz J, Rollins Y, Barohn RJ, Jackson CE, Tiryaki E, Lomen-Hoerth C, Armon C, Tandan R, Rudnicki SA, Rezania K, Sufit R, Pestronk A, Novella SP, Heiman-Patterson T, Kasarskis EJ, Pioro EP, Montes J, Arbing R, Vecchio D, Barsdorf A, Mitsumoto H, Levin B. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Annals of neurology 2009 Aug; 66(2).
Lin J, Diamanduros A, Chowdhury SA, Scelsa S, Latov N, Sadiq SA. Specific electron transport chain abnormalities in amyotrophic lateral sclerosis. Journal of neurology 2009 May; 256(5).
Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, Barkhaus PE, Bosch P, Boylan K, David WS, Feldman E, Glass J, Gutmann L, Katz J, King W, Luciano CA, McCluskey LF, Nash S, Newman DS, Pascuzzi RM, Pioro E, Sams LJ, Scelsa S, Simpson EP, Subramony SH, Tiryaki E, Thornton CA. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 2008 Nov; 71(22).
Karam C, Scelsa SN. Clinical Reasoning: A 48-year-old woman with generalized weakness. Neurology 2010 May; 74(18).
Gordon PH, Cheung YK, Levin B, Andrews H, Doorish C, Macarthur RB, Montes J, Bednarz K, Florence J, Rowin J, Boylan K, Mozaffar T, Tandan R, Mitsumoto H, Kelvin EA, Chapin J, Bedlack R, Rivner M, McCluskey LF, Pestronk A, Graves M, Sorenson EJ, Barohn RJ, Belsh JM, Lou JS, Levine T, Saperstein D, Miller RG, Scelsa SN. A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2008 Aug; 9(4).
Karam C, Scelsa SN. Clinical Reasoning: a 34-year-old woman with recurrent bouts of acral paresthesias. Neurology 2010 Mar; 74(9).
Shwe Y, Scelsa SN. A 23-year-old man with acute onset paresthesias and gait ataxia. Journal of clinical neuromuscular disease 2014 Jun; 15(4).
Kasarskis EJ, Mendiondo MS, Matthews DE, Mitsumoto H, Tandan R, Simmons Z, Bromberg MB, Kryscio RJ. Estimating daily energy expenditure in individuals with amyotrophic lateral sclerosis. The American journal of clinical nutrition 2014 Apr; 99(4).
Karam C, Barrett MJ, Imperato T, MacGowan DJ, Scelsa S. Vitamin D deficiency and its supplementation in patients with amyotrophic lateral sclerosis. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2013 Nov; 20(11).
Karam C, Scelsa SN. Clinical reasoning: a 79-year-old man with polyneuropathy and dysautonomia. Neurology 2011 May; 76(19).
Karam C, Scelsa SN. Can vitamin D delay the progression of ALS?. Medical hypotheses 2011 May; 76(5).
Deik A, Johannes B, Rucker JC, Sánchez E, Brodie SE, Deegan E, Landy K, Kajiwara Y, Scelsa S, Saunders-Pullman R, Paisán-Ruiz C. Compound heterozygous PNPLA6 mutations cause Boucher-Neuhäuser syndrome with late-onset ataxia. Journal of neurology 2014 Dec; 261(12).
Kasarskis EJ, Mendiondo MS, Wells S, Malguizo MS, Thompson M, Healey M, Kryscio RJ. The ALS Nutrition/NIPPV Study: design, feasibility, and initial results. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2011 Jan; 12(1).
Scelsa SN. Nitrous Oxide In: Experimental and Clinical Neurotoxicology, 2nd Ed. New York, Oxford University Press; pp882-889.
Herskovitz S, Scelsa SN, Schaumburg HH. Peripheral Neuropathies in Clinical Practice. . New York, Oxford University Press;.