David Dominguez-Sola

David Dominguez-Sola, MD, PhD

  • ASSOCIATE PROFESSOR | Oncological Sciences
  • ASSOCIATE PROFESSOR | Pathology, Molecular and Cell Based Medicine

Research Topics:

B Cells, Cancer, Cell Biology, DNA Replication, Gene Regulation, Immunology, Lymphocytes, Lymphoma, Molecular Biology, Transcription Factors, Transgenic Mice, Tumorigenesis

David Dominguez-Sola, MD, PhD, is Assistant Professor in the Departments of Oncological Sciences and Pathology at the Icahn School of Medicine at Mount Sinai (Icahn) and serves as faculty in Cancer Biology for the Graduate School of Biological Sciences, also at Icahn. He is a member of The Tisch Cancer Institute and the Precision Immunology Institute.

Originally trained as a hematopathologist, Dr. Dominguez-Sola’s scientific career has been focused on the study of pathogenesis of hematologic malignancies. Dr. Dominguez-Sola’s laboratory studies the molecular and cellular principles of cancer initiation and the underlying basis of precancerous states using B cell lymphomagenesis as reference model. They also conduct research on the mechanisms that support cancerous transformation in mature B cells, and how these relate to mechanisms supporting adaptive immune responses.

Dr. Dominguez-Sola has received numerous awards, including the Harold and Golden Lamport Research Award from the Icahn School of Medicine at Mount Sinai, Gabrielle’s Angel Foundation for Cancer Research Award, Leukemia Research Foundation New Investigator Award, Young Scientist Cancer Research Award from The Tisch Cancer Institute, and a K99/R00 Career Development Award from the National Institutes of Health (NIH)/National Cancer Institute (NCI). He is an ad-hoc reviewer for the NCI’s Small Grants Program for Cancer Research, and is also a reviewer for numerous journals, including Nature Communications, Journal of Experimental Medicine, Cell Reports, Journal of Cell Biology, Blood, Blood Advances, and Leukemia. His most recent grant funding from the National Cancer Institute supports the investigation of the role of FOXO1 mutations in the pathogenesis of B cell non-Hodgkin lymphomas.

Multi-Disciplinary Training Areas

Cancer Biology [CAB], Immunology [IMM]


MD, Autonomous University of Barcelona (UAB) Medical School

PhD, Pompeu Fabra University (UPF)

Columbia University