Kateri Moore, DVM
- PROFESSOR | Cell, Developmental & Regenerative Biology
Research Topics:Aging, Bioinformatics, Cell Adhesion, Cell Biology, Cell Cycle, Cell Division, Cellular Differentiation, Developmental Biology, Epigenetics, Gene Discovery, Genomics, Hematopoiesis, Mathematical Modeling of Biomedical Systems, Molecular Biology, Stem Cells, Transcription Factors, Transgenic Mice
My laboratory is studying both the basic biology and molecular mechanisms that make a hematopoietic stem cell a self-renewing stem cell that sustains our blood system throughout life. We do this by investigating these properties in model systems and by trying to convert other cell types into hematopoietic stem cells for eventual therapeutic uses. http://drb.mssm.edu/labs/lm.html
Multi-Disciplinary Training AreaDevelopment, Regeneration, and Stem Cells [DRS]
BS, Kansas State University
DVM, Kansas State University
Post Doctoral, Baylor College of Medicine
National Research Service Award
Hematopoietic Stem Cells Normal and Reprogrammed
Specific Clinical/Research Interest: Stem Cells/Microenvironment/Stem Cell Niche, Molecular regulation of hematopoietic stem cell self renewal and differentiation, molecular interaction of stem cells and microenvironmental elements. Direct differentiation of somatic cells into hematopoietic stem cells.
Current Students: Jeffrey Bernitz
Research Personnel: Ying Liu
Summary of Research Studies: Primary research interest is in defining the cellular and molecular nature of the hematopoietic stem cells (HSCs) and in particular the molecular cross-talk between stem cells and their niche. Approach is to use mouse models to study HSC during normal homeostasis and after stress. Also using specific factors to directly induce HSCs from somatic cells to develop patient specific stem cells and differentiated blood products for cell replacement therapies.