Samuele Marro, PhD
- ASSISTANT PROFESSOR | Neuroscience
Research Topics:Autism, Induced pluripotent stem cells, Neuroscience, Synaptic Plasticity
I received my PhD in Human Biology from the Molecular Biotechnology Center at the University of Torino in Italy. I was trained as a postdoctoral fellow in pluripotent stem cell biology in the laboratory of Marius Wernig, MD PhD, at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University.
I am currently an Assistant Professor in the Nash Family Department of Neuroscience and the Black Family Stem Cell Institute at the Icahn School of Medicine at Mount Sinai.
My team focuses on synaptic plasticity and its dysfunction in Fragile X syndrome, the number one genetic cause of autism. As a tool, the group uses human neurons directly differentiated from pluripotent stem cells and genetically modified using CRISPR/Cas9 tools.
I also serve as co-Director of the Stem Cell Engineering Core. This institutional Core provides services at a reduced cost to the Icahn School of Medicine community. Services include the derivation of iPS from patient blood samples, iPS differentiation into specific cell types, and gene-editing in iPS to create or repair putative disease mutations.