Thomas J Oxley

Thomas J Oxley, MD, PhD

  • INSTRUCTOR | Neurosurgery



Research Topics:

Amyotrophic Lateral Sclerosis, Biomechanics/Bioengineering, Electrophysiology, Epilepsy, MRI, Motor Control, Muscular Dystrophy, Neuromodulation, Neurophysiology, Rehabilitation, Spinal Cord, Stroke

Thomas J. Oxley, MD, PhD, is an instructor and Director of Innovation Strategy for the Department of Neurosurgery at the Mount Sinai Health System. As part of the Cerebrovascular Center, he specializes in vascular neurosurgery and interventional neurology, including the treatments of stroke, brain aneurysms, and vascular malformations. In his strategic role in the new Sinai BioDesign Center, he assists faculty members in the development of novel devices and technologies. The center already has over 20 projects in development and is currently seeking new concepts. 

Dr. Oxley is the founder and CEO of Synchron, a neural interface technology company. The internationally acclaimed stentrode device can record brain activity from within a blood vessel. In the intended application of the technology, the user’s thoughts are captured, decoded and passed wirelessly through the skin to enable control of digital devices that enable movement and speech restoration to previously paralyzed patients. A human clinical trial is close to commencement.

Dr. Oxley completed his PhD in neural engineering at the University of Melbourne, then completed both internal medicine and neurology residencies, as well as a stroke fellowship, in Australia. He performed his endovascular neurosurgery fellowship alongside Dr. Kellner at Mount Sinai under the direction of Drs. Mocco, Berenstein, Fifi, and De Leacy.

Dr. Oxley was published as first author in Nature Biotechnology for his research on “Minimally Invasive Endovascular Stent-Electrode Array for High-Fidelity, Chronic Recordings of cortical neural activity.” He has also published 30 internationally peer-reviewed articles that have accumulated 2080 citations with an H Index of 10.

Clinical Focus

  • Amyotrophic Lateral Sclerosis
  • Aneurysm Coiling
  • Brain Aneurysm
  • Brain Tumors
  • Carotid Artery Stenosis
  • Carotid Stenting
  • Cavernous Malformations
  • Cerebral Vasospasm
  • Dural Arteriovenous Fistula (DAVF)
  • Endovascular Embolization
  • Facial Arteriovenous Malformations
  • Facial Vascular Malformations
  • Hemangioblastoma
  • Mechanical Thrombectomy
  • Spinal Vascular Malformations
  • Stroke
  • Subarachnoid Hemorrhage
  • Vascular Malformations
  • Venous Sinus Thrombosis


MD, Monash University

Residency, Neurology, Alfred Hospital

Residency, , Albury Hospital

Residency, Neurology, Royal Melbourne Hosp

Fellowship, Stroke Fellowship, Royal Melbourne Hospital

Fellowship, Vascular Neurology, The Mount Sinai Hospital

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