Mount Sinai Tisch Cancer Center

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Cancer Mechanisms

Cancer Mechanisms

The goal of the CM program is to catalyze basic research pertinent to cancer-relevant mechanistic discovery to generate new knowledge leading to enhanced diagnosis, treatment, and prevention of primary cancer and systemic recurrence of cancers highly represented in the TCI immediate catchment area. CM is dedicated to exceptional basic research concentrating on the tumor microenvironment (TME), cell signaling pathways, and epigenetic and transcriptional control in cancer.

Program Goals

  • Investigate cellular interactions within the tumor microenvironment
  • Elucidate cell signaling networks in cancer
  • Investigate epigenetics and gene regulation of tumor biology
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Cancer Mechanisms Research Program Leaders

Emily Bernstein, PhD
Emily Bernstein, PhD
PROFESSOR | Oncological Sciences
PROFESSOR | Dermatology
PROFESSOR | Stem Cell Biology And Regenerative Medicine
Poulikos Poulikakos, PhD
Poulikos Poulikakos, PhD
PROFESSOR | Oncological Sciences

Members

AT A GLANCE

Cancer Mechanisms Research

3237
Publications
1106
Press/Media

55 Researchers

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Recent Publications

Characterization of inflammatory skin conditions and autoimmune conditions in solid organ transplant patients at a large metropolitan academic center. JAAD International

EGFR-mutant transformed small cell lung cancer harbors intratumoral heterogeneity targetable with MEK inhibitor combination therapy. JCI insight

Anti-FAP CAR T cells produced in vivo reduce fibrosis and restore liver homeostasis in metabolic dysfunction–associated steatohepatitis. Science Translational Medicine

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Moving the Field Forward

Find out how we collaborate to address cancer’s most complex challenges.

The Lung Cancer Program at the Mount Sinai Tisch Cancer Center
Mount Sinai's Cancer Clinical Trials
Stuart A. Aaronson, MD: 2024 Jacobi Medallion Recipient
Thomas Marron, MD, PhD – AACR Annual Meeting 2023
Ramon Parsons, MD, PhD: 2023 Jacobi Medallion Recipient
2022 Distinguished Scholar Award - Dr. Alice Kamphorst
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Resources For You

TCI Newsletter
Cancer Centers of Excellence
Patient Care
Residencies and Fellowships
Facing Our Risk of Cancer Empowered (FORCE)
Cancer InFocus: Explore Cancer Data in NYC

Contact Us

Mount Sinai Tisch Cancer Center

One Gustave L. Levy Place

Box 1128

New York, NY 10029-6574

Christine Ponder, PhD, MPA
Director, Research Administration

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Patient Information
The Clinical Research Support Unit

212-824-7391
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