Institute for Regenerative Medicine

Bernstein Lab
The Bernstein Lab focuses on the study of histone variants and ATP-dependent chromatin remodeling complexes in cancers.

Chaudhry Lab
The Chaudhry Lab is dedicated to the study of cell cycle biology in cardiac development and its application to the treatment of heart disease.

Fang Lab
The Fang Lab focuses on the mechanistic understanding of regulatory factors maintaining cell identity and driving cell lineage commitment during musculoskeletal tissue development, mechanical adaptation, and pathogenesis.

Han Lab
The Han Lab applies biomaterials and bioengineering approaches to study skeletal muscle-resident stem and progenitor cell mechanobiology, cell-matrix interactions, and disease modeling.

Iatridis Lab
The Iatridis Lab develops minimally invasive interventions to prevent and repair painful spinal pathologies with a focus on intervertebral disc degeneration.

Krauss Lab
The Krauss Lab focuses on how cell-cell adhesion and signal transduction pathways interact to regulate cell fate during embryonic developmental and adult tissue regeneration.

Ma Lab
The Ma Lab develops cutting-edge single-cell sequencing approaches to probe gene regulation mechanisms and cell fate transitions in development and diseases.

Marlow Lab
The Marlow Lab exploits the powerful genetics and cell biological access in the zebrafish system to unravel the mechanisms that regulate oocyte polarization and follicle cell fate in a vertebrate.

Millar Lab
The Millar Lab focuses on the roles of Wnt signaling and transcriptional and epigenetic regulatory mechanisms in development and regeneration of epithelial tissues and their appendages.

Mlodzik Lab
The Mlodzik Lab studies Wnt/frizzled-planar cell polarity signaling and associated regulatory and signaling specificity mechanisms.

Rangan Lab
The Rangan Lab investigates female fertility and developmental defects utilizing the female germ line in the developmental context of the fruit fly, Drosophila melanogaster.

Rendl Lab
The Rendl Lab utilizes the hair follicle as a mini-organ to study how stem cells are regulated by their microenvironment or niche.

Ying Lab
The Ying Lab studies the causal relationship between cancer lesions, environmental cues, tissue damaging stresses and epithelial cell fate choice in homeostasis, malignant growth, and tissue regeneration.

Yuan Lab
The Yuan Lab is dedicated to developing and applying innovative computational methods to gain a systems-level understanding of life.

Zangi Lab
The Zangi Lab’s research is centralized around modified mRNA as an attractive and novel in vivo gene delivery method that allows high gene expression in a variety of organs, including the heart.

Baron Lab
The Baron Lab is interested in molecular mechanisms of hematopoietic stem and progenitor cell fate specification and differentiation using mouse and human primary cells, embryonic stem cell models, and mice.

Bieker Lab
The Bieker Lab focuses on the regulation of gene expression during erythropoiesis.

Ghaffari Lab
The Ghaffari Lab is interested in the prevention of chronic blood disorders, leukemias, and aging blood by targeting organelles like lysosomes and mitochondria in stem cells.

Horowitz Lab
The Horowitz Lab focuses on human NK cells and T cells and their functional roles in cancer, microbial infections, transplantation, and in autoimmunity.

Sturgeon Lab
The Sturgeon Lab is focused on understanding hematopoietic development, using both human pluripotent stem cells and model organisms, to develop novel cell-based therapeutics.

Wagenblast Lab
The Wagenblast Lab seeks to understand how a normal blood stem cell can become cancerous.

Chen Lab
The Chen Lab focuses on applying human pluripotent stem cell-derived lung organoids as a model to study the mechanisms of lung injury repair, stem cell-based therapy, disease modeling, and regenerative medicine.

Ezhkova Lab
The Ezhkova Lab is interested in how epigenetic regulation controls cell function in all stages of life, including development, adulthood, during aging, and in non-homeostatic situations, such as when healing wounds or in cancer.

Ji Lab
The Ji Lab seeks to better understand cell-cell interactions by leveraging single-cell and spatial multi-omic approaches applied directly to patient tissue, veridical human tissue models, and mouse models of skin disease.

Kathiriya Lab
The Kathiriya Lab researches mechanisms underlying early activation of lung epithelial progenitors after injury and cytoskeletal remodeling underpinning cell differentiation.

Kim Lab
The Kim Lab explores basic approaches and techniques in innate immunity, neuroimmunology, and behavioral modeling of chronic itch.

May Lab
The May Lab aims to define causative mechanisms of numerous diseases through defining alterations in the structure and function of epithelial organs.

Millar Lab
The Millar Lab focuses on the roles of Wnt signaling and transcriptional and epigenetic regulatory mechanisms in development and regeneration of epithelial tissues and their appendages.

Rendl Lab
The Rendl Lab utilizes the hair follicle as a mini-organ to study how stem cells are regulated by their microenvironment or niche.

Silva Lab
The Silva Lab uses state-of-the-art genomics, functional studies, and systems biology methods to generate functional maps and pinpoint key regulatory hubs that, when perturbed, compromise cancer cell viability.

Sun Lab
The Sun Lab is dedicated to unraveling the intricate mechanisms underlying the shaping of cell identity and how these processes contribute to the adaptation or promotion of physiological and pathological processes.

Tsankov Lab
The Tsankov Lab uses genomics to build data-driven, predictive models that improve diagnosis, find new druggable pathways, and personalize treatment of patients with lung cancer and respiratory diseases.

Azeloglu Lab
The Azeloglu Lab uses multidisciplinary approaches to understand how the human body operates and malfunctions, and aims to utilize engineering approaches for design of new therapeutic strategies against complex diseases such as diabetic nephropathy and heart failure.

Blanchard Lab
The Blanchard Lab engineers 3D models of human brain tissue from stem cells and applies these models to understand and therapeutically target risk factors for Alzheimer’s disease and other forms of cognitive impairment.

Blenkinsop Lab
The Blenkinsop Lab studies the plasticity of the adult human eye in normal and pathological states with an emphasis on the role of the retinal pigment epithelium, a layer of cells supporting the photoreceptors of the retina.

Buxbaum Lab
The Buxbaum Lab studies human psychiatric and neurological diseases using methods of epidemiology, genetics, genomics, molecular and cell biology, and animal models.

Chen Lab 
The Chen Lab focuses on applying human pluripotent stem cell-derived lung organoids as a model to study the mechanisms of lung injury repair, stem cell-based therapy, disease modeling, and regenerative medicine.

Gelb Lab
The Gelb Lab is focused on improving care for individuals with congenital heart defects and their families by using genetic approaches to understand the fundamental causes of congenital heart defects and then using that information to improve outcomes.

Goate Lab
The Goate Lab focuses on dementia and addiction, and the molecular basis of these diseases in order to identify novel targets for therapeutic development.

Guccione Lab
The Guccione Lab studies the function of methyltransferases in development and disease.

Sturgeon Lab
The Sturgeon Lab is focused on understanding hematopoietic development, using both human pluripotent stem cells and model organisms, to develop novel cell-based therapeutics.

Wagenblast Lab
The Wagenblast Lab seeks to understand how a normal blood stem cell can become cancerous.

Yang Lab
The Yang Lab is interested in the neurobiological foundations underlying the causes, mechanisms, and trajectories of psychiatric and neurological disorders.

Zwaka Lab
The Zwaka Lab focuses on understanding mammalian cellular diversity.

Blanchard Lab
The Blanchard Lab engineers 3D models of human brain tissue from stem cells and apply these models to understand and therapeutically target risk factors for Alzheimer’s disease and other forms of cognitive impairment.

Bond Lab
The Bond Lab uses cutting-edge cellular and molecular techniques to investigate neural stem cell function in different contexts, including during development, across the lifespan, and in response to experience.

Buxbaum Lab
The Buxbaum Lab studies human psychiatric and neurological diseases using methods of epidemiology, genetics, genomics, molecular and cell biology, and animal models.

Castellano Lab
The Castellano Lab seeks to understand pathways connecting the systemic environment to brain function in the context of neurodegenerative diseases.

Chen Lab
The Chen Lab is interested in understanding virus host interactions that cause disease in humans.

Elahi Lab
The Elahi Lab seeks to understand vascular contributions to cognitive impairment and dementia, and to develop new therapies that protect brain function in the face of Alzheimer's, CADASIL, and other neurodegenerative diseases.

Goate Lab
The Goate Lab focuses on dementia and addiction, and the molecular basis of these diseases in order to identify novel targets for therapeutic development.

Kim Lab
The Kim Lab explores basic approaches and techniques in innate immunity, neuroimmunology, and behavioral modeling of chronic itch.

Tsankova Lab
The Tsankova Lab seeks to understand the cellular and molecular mechanisms driving aberrant glial proliferation and migration in two debilitating central nervous system disorders—glioblastoma and epilepsy—focusing on the role of epigenetics and the transcriptional machinery in maintaining these dysfunctional glial phenotypes.

Yang Lab
The Yang Lab is interested in the neurobiological foundations underlying the causes, mechanisms, and trajectories of psychiatric and neurological disorders.

Yuan Lab
The Yuan Lab is dedicated to developing and applying innovative computational methods to gain a systems-level understanding of life.