At the Center for Advancement of Blood Cancer Therapies, our researchers publish articles in leading scientific journals reporting discoveries of new disease mechanisms and therapeutic targets.
- Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells, Nat Cell Biol, 2022
- Integrative RNA-omics Discovers GNAS Alternative Splicing as a Phenotypic Driver of Splicing Factor-Mutant Neoplasms. Cancer Discovery, 2022
- A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia, Blood, 2022
- Mapping the cellular origin and early evolution of leukemia in Down syndrome. Science, 2021
- Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets. Cell Stem Cell, 2021
- Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development, Dev Cell, 2020
- Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency, Cell Stem Cell, 2020