To support comprehensive data management and analysis, our BioMe team at The Institute for Personalized Medicine created an efficient and integrated pipeline environment called the BioMe Informatics and Genomic Data Analysis Center (BIGDASC).
BIGDASC provides access to de-identified phenotypic information in the Biobank Clinical DataMart, which is updated weekly from the Mount Sinai Data Warehouse. Genotype-phenotype association studies are enabled on a project level through access to de-identified genotypic/sequence information deposited in the BioMe Database, or through de novo genotype/sequence analysis of de-identified samples tracked in the BioMe LIMS (Laboratory Information Management System).
Diseases groups include the following and many more:
- Crohn’s disease
- Hepatitis C and other hepatology disorders
- Kidney disease in African Americans with high blood pressure
- Inherited causes of abdominal aortic aneurysms
- Disparities in metabolic, heart, and kidney disorders among Hispanics and African Americans
- Genetic studies of the Ashkenazi Jewish population
- Pediatric allergic disorders
- Rheumatologic, dermatologic, and immunologic disorders
- Multiple sclerosis