1. Research
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Metabolism and Lipids Program

The Metabolism and Lipids Program at the Icahn School of Medicine at Mount Sinai focuses on cardiovascular health. We provide patient care, perform translational research, and offer a medical fellowship. Throughout all our activities, our goal is to improve patient care and outcomes.

Research

We design and conduct several types of translational studies on cardiovascular health and metabolic disorders. First, we perform translational research emphasizing lipoproteins, inflammation, and thrombosis. Second, we explore machine learning, integrating classic risk factors, genetics, and imaging. Finally, we use real world data to assess trends in use adherence and persistence of lipid-altering therapies.

Education

Our Advanced Fellowship in Preventive Cardiology provides in-depth, broad-based, multidisciplinary training in clinical cardiovascular risk factor detection and cardiometabolic disease prevention and management. Our fellows also receive a firm grounding in clinical research. Fellows learn about topics such as:

  • Lipoprotein disorders
  • Essential and secondary causes of hypertension
  • Obesity and weight management
  • Diabetes
  • Chronic renal disease
  • Metabolic dysfunction-associated steatotic liver disease and steatohepatitis
  • Behavior medication

Fellows also participate in translational research studies, gaining experience in areas including clinical trials, atherosclerosis imaging, genetic epidemiology, machine learning, and thrombosis. 

Some students in other programs at Icahn Mount Sinai have assisted researchers in the Metabolism and Lipids Program. They gain one-on-one training in specific techniques related to lipoproteins and atherosclerosis, such as management of protein disorders and cardiovascular risk factors. 

Patient Care

Our patient care focuses on cardiovascular preventive care with an emphasis on evidence-based diagnosis and treatment of metabolic disorders. We have a specific focus on treatment of lipoprotein disorders. We perform enhanced risk assessments by analyzing biomarkers, genetics, and atherosclerosis imaging. We offer guidance on lifestyle changes, with specific counseling on nutrition and exercise. In addition, our patients have the opportunity to participate in mechanistic studies as well as phase 2 and phase 3 clinical trials. 

How to Give

To make a gift to support this work or for more information about philanthropic opportunities, please contact Todd Brooks, Senior Director of Development, at 332-271-5872 or todd.brooks@mountsinai.org.

Meet the Director

Faculty

Robert Rosenson, MD
Robert Rosenson, MD

Director, Metabolism and Lipids Program

Waqas Malick, MD
Waqas Malick, MD
ASSISTANT PROFESSOR | Medicine, Cardiology
Sean A Kotkin, MD
Sean A Kotkin, MD
ASSISTANT PROFESSOR | Medicine, Cardiology
Jeffrey I Mechanick, MD
Jeffrey I Mechanick, MD

Professor, Medicine (Cardiology)

Research Collaborators

Leslee Shaw, PhD
Leslee Shaw, PhD

Professor, Medicine (Cardiology)

Ron Do, PhD
Ron Do, PhD
PROFESSOR | Genetics and Genomic Sciences
Gina LaRocca, MD, MHSc
Gina LaRocca, MD, MHSc

Associate Professor | Medicine, Cardiology

Juan J Badimon, PhD
Juan J Badimon, PhD
PROFESSOR | Medicine, Cardiology