This research study is being conducted in a network of community health centers and primary care facilities located in the New York City neighborhoods of Harlem and the Bronx to study the effects and challenges of incorporating genetic risk information in clinical care for patients of African ancestry with high blood pressure and at risk for chronic kidney disease (CKD).

Recent discoveries show that variations in the APOL1 gene make people with high blood pressure have a higher risk of developing kidney disease. Variations in the APOL1 gene are much more common in people with African ancestry and very rare in people of European ancestry. A special blood test can show if one has variations in this gene. As part of this study, a group of patients will be tested for the APOL1 gene variations, and the results of the test will be given to them and their providers. The purpose of this study is to learn whether getting the APOL1 genetic test is helpful to patients and their providers.

This study is currently enrolling study participants who see their providers at the following clinical sites:
- Mount Sinai Internal Medical Associates (IMA)
- Mount Sinai Faculty Practice Associates (FPA)
- Family Health Center of Harlem
- Sidney Hillman
- Walton Health Center (Bronx)
- Stevenson Health Center (Bronx)

Participants must also meet the following criteria:
- Have high blood pressure
- Be between ages 18-65
- Of African American or Black race
- No diabetes
- No kidney problems

If volunteers enroll, they will receive a free genetic test that can show if they have an increased risk for kidney disease. Participants must also come to 3 study visits of about one hour each where the study team will ask some questions about their health and complete a health assessment. Each participant must also come to a visit where the study team will explain the results of the test. Participants will receive compensation as a thank you for their time.

Faculty

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