Glial Biology

The Center for Glial Biology at the Icahn School of Medicine at Mount Sinai focuses on understanding the basic mechanism underlying glia biology and glia-neuron interactions in the brain, and developing innovative approaches to maintain and extend healthy brain function. We strive to achieve breakthroughs in understanding the principles that govern glia-mediated developmental and age-associated diseases in the central nervous system, pioneer new strategies targeting glia cells for restoring and maintaining a normal health and lifespan, and prevent age-associated neurodegenerative diseases.

Icahn Mount Sinai was among the first research centers in the world that recognized the significance of microglia and made several important contributions to the field. In addition, we have a strong program on studies elucidating the significant role of glia cells in developmental diseases, including autism, epilepsy, and substance abuse disorders. Our esteemed faculty are exploring the pivotal roles of microglia through various research areas including neurodevelopment and psychiatric diseases, microglia neurodegeneration, and astrocytes and endothelia cells. The researchers in these areas include: