Jeff and Lisa Blau Adolescent Consultation Center for Resilience and Treatment

Clinical and Neurobiological Research

Despite significant advances in the understanding of the neurobiology and genetics of severe mental illness in recent decades, few new treatments have emerged using other modalities or addressing other mechanisms. The Blau Center aims to accelerate the development of novel and breakthrough therapeutics by advancing cutting-edge research at the intersection of neurobiology, genetics, and artificial intelligence. We are translating these insights into innovative, patient-centered treatments.

To learn more, please email blaucenter@mssm.edu or call us at (917) 576-4787.

Mental Health Chatbot Study

Many people already use publicly available AI tools without safeguards, but little is known about how these interactions affect their mental health. In this study, we explore how artificial intelligence can be safely and meaningfully used in mental health care. We study how people with a broad range of mental health conditions naturally interact with a secure, Mount Sinai-hosted chatbot.

Psychiatry Vision Wearable Study

Today, psychiatric assessments often depend on clinician judgment and what patients report about their own experiences. By adding measurable behavioral signals, we hope to make evaluations more consistent, accurate, and informative across different care settings. In this study, we are testing whether smart glasses worn by our team can improve how mental health conditions are evaluated by capturing objective information (like where someone looks, how they move, and how they speak) during real clinical visits.

Family Genetic Study

In some people, rare genetic differences may play a role in why certain conditions like schizophrenia, epilepsy, and neurodevelopmental disorder develop. This study aims to better understand these genetic changes. By looking at how these rare variants are passed down in families and how they affect health, we hope to uncover new insights that could lead to improved diagnosis and treatment.

Parkinson’s Vision Wearable Study

Today, Parkinson’s assessments often rely on brief clinic visits and rating scales, which may miss important day-to-day changes in symptoms. By using AI-powered technology, we aim to measure movement more precisely, better understand different types of Parkinson’s, and help doctors fine-tune treatments like deep brain stimulation for each patient. This study uses Apple Vision Pro to track how people move to improve our understanding and treatment of Parkinson's.

Mount Sinai Million

The Mount Sinai Million Health Discoveries Program is open to all Mount Sinai patients. Participants can choose to share their health information and leftover samples to help researchers better understand the causes of disease. This work supports the development of new ways to prevent, diagnose, and treat a wide range of conditions, ultimately improving care for future patients. By enrolling in the Mount Sinai Million, patients become eligible for other research studies across the health system.