Supported Studies
The HIMC is actively involved in a large number collaborative research projects with both academic and industry partner, including serving as a central immune monitoring resource for several large consortium grants. Here is a list of funded studies that HIMC has supported across a range of research areas. When you click on each entry in the list, you will link over to the NIH listing for that grant.
- R01 Harnessing Csf-2 compartmentalized role on tissue resident phagocytes to uncouple anti-tumoral from pathological immunity induced by checkpoint inhibitors.
PI: Miriam Merad - U24 High-dimensional immune monitoring of nci-supported immunotherapy trials.
PI: Sacha Gnjatic - U24 Novel tools to maximize profiling of tissue and antigen specific immune dysregulation in allergy and inflammatory bowel disease.
PI: Miriam Merad - P30 The Tisch Cancer Institute - Cancer Center Support Grant
PI: Ramon Parsons
- R01 Evaluation of HCC Response to Systemic Therapy with Quantitative MRI
PI: Bachir Taouli - Characterization of Prostate Cancer Aggressiveness with Advanced Multiparametric Magnetic Resonance Imaging
Prostate Cancer Foundation
PI: Bachir Taouli - MRI-Based Surrogate Imaging Markers of Transcriptome Subclasses and Signatures in Hepatocellular Carcinoma
Type: Foundation (RSNA)
PI: Bachir Taouli - R01 Clinical Targeting of Prostate Cancer Dormancy
PI: Julio A. Aguirre-Ghiso and Dr. Samuel Sidi - P01 Personalized Immunotherapy of Patients with Ovarian Cancer
PI: David Spriggs - R21 Biological Effects of Systematic Light Exposure for Cancer-Related Fatigue
PI: William Redd
- R21 Inflammatory and Neurocircuit Mechanisms of Anhedonia in Human Depression
PI: PI: James Murrough - R01 The Neuroimmunology of Anhedonia
PI: Vilma Gabbay - R01 The Role of Peripheral Myeloid Cells in Alzheimer Disease (AD)
PI: Towfique Raj - R37 Histone Deacetylation in Oligodendrocyte Differentiation
PI: Patrizia Casaccia
- R01 Neuroinflammation and PVS Deficits in Adolescents
PI: Vilma Gabbay
- U01 Neurocircuitry of Impaired Insight in Addiction
PI: Bety Casey
- P01 Stress and Atherosclerotic Plaque Macrophages – a Systems Biology Approach
PI: Zahi Zayad - Delineating the Triggers and Impact of Pathologic Cardiac Remodeling Following Premature Birth
The American Heart Association
PI: Alan Groves - K23 Role of Alternatively Spliced Tissue Factor in Atherosclerosis
PI: Chiara Giannarelli
- R03 Dissecting the Cellular and Molecular Immune Interactions in Atherosclerosis
PI: Chiara Giannarelli
- R21 Network-Driven Drug Repurposing Approaches to Treat Coronary Artery Disease
PI: Chiara Giannarelli
- UH2 Single-Cell-Driven Drug Repositioning to Target Inflammation in Atherosclerosis
PI: Chiara Giannarelli
- Characterizing the Single Cell Expression of the IL23 Receptor (IL23R) in Crohn's Disease (CD) Patients Utilizing CyTOF Technology
Department of Medicine Junior Faculty Translational Collaborative Research Initiative Grant
PI: Ryan Ungaro - U24 Novel tools to maximize profiling of tissue and antigen specific immune dysregulation in allergy and inflammatory bowel disease.
PI: Miriam Merad
The HIMC serves as a central immune monitoring center for several large multicenter consortia.
- U24 CIMAC: High-Dimensional Immune Monitoring of Nci-Supported Immunotherapy Trials
PI: Sacha Gnjatic (Mount Sinai)
- U19 HIPC: Human Anti-Viral Immune Responses in Tissues and Circulation
PI: Donna Farber (Columbia)
- U19 HIPC: Dengue Human Immunology Project Consortium (DHIPC)
PI: Anna Sesma (Mount Sinai) and Eva Harris (UC Berkeley)
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U01 Mount Sinai School of Medicine Inflammatory Bowel Disease Genetics Research Center
PI: Judy Cho - U10 Dry Eye Evaluation and Management (DREAM) Study
ABCD-USA: NYC Research Project
PI: Penny Asbell
In addition to academic studies, the HIMC has extensive experience with supporting immune monitoring studies sponsored by several industry collaborators including Celgene, BMS, Janssen, Pfizer, Takeda, Immune Design, Gradalis, TapImmune, AstraZeneca, Genetec, and DynaVax.