Mount Sinai Center for Sickle Cell Disease

The Mount Sinai Center for Sickle Cell Disease at the Icahn School of Medicine provides comprehensive care to more than 1400 individuals with sickle cell disease across their lifespan, making it one of the largest programs in the country. The Center is a leader in clinical care and provides access to cutting-edge therapies and research that is supported by more than $25 million in funding. Our program has one of only two dedicated Sickle Cell Disease Fellowships for advanced physician training in the United States.

Sickle Cell Disease

Sickle cell disease is caused by abnormal types of hemoglobin, a protein inside red blood cells that carries oxygen. The abnormal hemoglobin, called hemoglobin S, causes red blood cells to become fragile and look like crescents or sickles. While hemoglobin S is the most common abnormality, there are other types of abnormal hemoglobin, such as hemoglobin C, that can also cause sickle cell disease. The abnormal red blood cells deliver less oxygen to tissues in the body and can get stuck in small blood vessels, interrupting healthy blood flow. Sickle cell disease is inherited from both parents. It is more common in people of African and Mediterranean descent. At Mount Sinai, we treat all types of sickle cell disease as part of our benign hematology services.

Our Program

The Mount Sinai Center for Sickle Cell Disease offers comprehensive care and the most advanced breakthroughs in treatments that dramatically improve outcomes for patients. We join clinical care and scientific research with psychosocial services to provide the best care available anywhere. Our team includes dedicated physicians, advanced practice providers, and social workers who specialize in sickle cell disease and who expertly manage both the acute and chronic complications that sickle cell disease may cause, as well as its psychosocial challenges.

Research and Clinical Trials 

We offer patients with sickle cell disease the opportunity to participate in translational research studies aimed at improving patient outcomes and quality of life.

View our clinical trials

Care for Pediatric Patients 

We provide specialized care for children with sickle cell disease and are equipped to treat complications such as stroke and acute chest syndrome in collaboration with Mount Sinai’s Pediatric Intensive Care Unit.  We work closely with your child’s pediatrician to diagnose and treat sickle cell disease and to provide patient and family education. We also provide opportunities to participate in support groups, camps, and other extracurricular activities.