Systems Biology Center of New York

Systems Pharmacology

The global relationship between therapeutic drugs and human genome is largely unexplored. Systems pharmacology is focused on understanding drug action both therapeutic and adverse from a network perspective with the goal of anchoring all drug action in the human interactome. Such a holistic approach will be useful both for drug discovery, especially polypharmacology for complex diseases and prediction of adverse events. One long-term goal is to be able to develop algorithms that predict therapeutic efficacy and adverse event probability in individual patients. Members of SBCNY are actively working in the area of systems pharmacology and have made some of the earliest contributions to this emerging field.

Systems pharmacology papers published by SBCNY researchers 

View a complete list of publications by our researchers