Crawford W. Long, MD, an American surgeon, administers the first ether anesthetic using inhaled sulfuric ether.

Horace Wells, a dentist, is the first person to self-anesthetize with nitrous oxide.

William T.G. Morton, a dentist, administers an ether anesthetic at Massachusetts General Hospital.

John Snow, MD, administers chloroform to Queen Victoria for labor and delivery.

The Jews' Hospital on West 28th Street—founded in 1855 to provide free medical care to indigent Jews—becomes The Mount Sinai Hospital.

The Mount Sinai Hospital moves to East 67th Street.

The first spinal anesthetic was administered by August Bier, a German surgeon.

Trained anesthesiologists begin working at The Mount Sinai Hospital.

Trained anesthesiologisThe Mount Sinai Hospital moves to its current location on Fifth Avenue and 100th Street.ts begin working at The Mount Sinai Hospital.

The American Society of Anesthesiologists is founded.

The modern-day laryngoscope with Miller and Macintosh blades becomes available.

The modern-day laryngoscope with Miller and Macintosh blades becomes available.

The Mount Sinai Hospital’s Department of Anesthesiology is created under the direction of Bernard Eliasberg, MD, a founder of the New York State Society of Anesthesiologists.

The Mount Sinai School of Medicine is established (now the Icahn School of Medicine at Mount Sinai).

The first pulse oximeter becomes commercially available and, in 1987, pulse oximetry was added as a standard of basic anesthetic monitoring by the American Society of Anesthesiologists

The first video laryngoscope is commercially available 

The Department's Human Emulation, Education, Evaluation, Lab for Patient Safety and Professional Study (HELPS) Center is created.

The HELPS Center is officially accredited by the American Society of Anesthesiologists and becomes one of the nation’s busiest training sites.

The medical school is renamed the Icahn School of Medicine at Mount Sinai

The Mount Sinai Hospital merges with Continuum Health Partners and adds six hospitals to its network.

The Department becomes responsible to provide anesthesiology coverage at St. Luke's-Roosevelt Hospitals (now Mount Sinai Morningside and Mount Sinai West) and oversees a second residency training program based at Mount Sinai Morningside and Mount Sinai West Hospitals. The Department becomes one of the 10 largest training programs in the United States.

The Department is renamed the Department of Anesthesiology, Perioperative and Pain Medicine, and provides more than 100,000 anesthetics a year across its four hospital locations.

The Department opens a freestanding Pain Management Practice on West 57th Street in Manhattan.

The Department becomes responsible for providing anesthesiology services at Mount Sinai Brooklyn (formerly Beth Israel Kings Highway) and expands its Pain Management practice to Brooklyn.

The Department forms a new Joint Venture with U.S. Anesthesia Partners, to provide service in multiple new ambulatory surgery centers being added to the Mount Sinai Health System. The Department is poised to provide 120,000 anesthetics annually.