Director

Robert Sebra, PhD, Professor of Genetics and Genomic Sciences, directs the Center for Advanced Genomics Technology (CAGT) at the Icahn School of Medicine at Mount Sinai. Dr. Sebra led technology development for the former Icahn Institute for Data Science and Genomic Technology for eight years. He has also served as vice president at Sema4 (a Mount Sinai venture) and has led technology adoption in research and development to help create high-throughput diagnostics and drive innovative platforms toward translational utility. An expert in applied genomic sciences who publishes widely, Dr. Sebra has experience in molecular, biochemical, and sequencing technology including surface bioconjugation techniques, microfluidics platforms, active biomaterials, single-molecule chemistry, and the integration of bulk, single-cell, and spatial sequencing technologies. Prior to joining Mount Sinai, he participated in research and development contributing to patents involved in the generation of single-molecule real-time long-read sequencing technology and applications at Pacific Biosciences. He earned his PhD in chemical and biological engineering at the University of Colorado, Boulder.

Faculty and Leadership

Our faculty and leadership include the following experts:

Kristin Beaumont, PhD, Associate Director and Assistant Professor, Genetics and Genomic Sciences. Dr. Beaumont uses single-cell and spatial transcriptomic analysis expertise to spearhead research investigating the role of heterogeneity in cancer metastasis. 

Michael Beaumont, PhD, Assistant Director and Assistant Professor, Genetics and Genomic Sciences. Dr. Beaumont leverages his functional genomics, tissue engineering, and neuroscience expertise to lead research toward understanding the genetic-phenotypic relationships of neural circuit dynamics and pathology in diverse disease states.

Project operations are led by Maya Fridrikh, MS (single-molecule technologies), Aana Hahn (high-throughput NGS platforms), Mandy Tin (single-cell and spatial technologies), and Hardik Shah (informatics).

To date, the team has contributed to more than 130 collaborative publications and played a significant role in multidisciplinary grant acquisition across the Mount Sinai community.