Our research focuses on the immediate and long-term effects of psychedelic-assisted therapy (PAT) and development of treatment protocols for PTSD, depression, and other trauma-related conditions. Incorporating clinical and neurobiological approaches, our work has included groundbreaking research on trauma, PTSD, and the intergenerational effects of trauma with combat veterans, Holocaust survivors and their descendants, 9/11 responders, and survivors of sexual assault. Our multi-modal approach includes systems biology and epigenetics, neuroimaging, and audiovisual treatment data. In partnership with the James J. Peters VA and the Icahn School of Medicine, we aim to better understand trauma’s complex effects and develop effective, evidence-based strategies to reduce suffering and support long-term healing.