Andrea Dunaif, MD, is a Professor of Medicine, Endocrinology, Diabetes and Bone Disease, and Chief, Division of Endocrinology, Diabetes and Bone Disease. Her research has been at the forefront of studies on the genetic basis of PCOS. She demonstrated that hyperandrogenemia was the cardinal reproductive phenotype in PCOS families and has mapped several genetic susceptibility loci associated with this phenotype. Dr. Dunaif was the first to show that male and non-reproductive-age female relatives of women with PCOS have reproductive and metabolic phenotypes. Most recently, she has extended this work to show that premenarchal girls and infants have reproductive and metabolic phenotypes, including evidence that they are already at high risk for type 2 diabetes. Her team has recently completed two genome-wide association studies to identify genetic loci associated with PCOS and its quantitative traits in women with PCOS of European and Han Chinese ancestry. She has mapped the first replicated genetic locus for PCOS as a variant within the fibrillin-3 gene. She is the Principal Investigator for the study.
Sherley Abraham, MD, is an Assistant Professor in the Division of Endocrinology, Diabetes and Bone Disease at Icahn School of Medicine at Mount Sinai. Dr. Abraham is a scientist and clinician with broad experience in healthcare and academic medicine. She is board certified in Endocrinology, Diabetes, and Metabolism as well as Internal Medicine. After graduating from the SUNY Stony Brook School of Medicine, she completed her Residency at the NYU School of Medicine. Dr. Abraham then completed a Fellowship in Hypertension and Lipidology in the Physician-Scientist Training Program at the NYU School of Medicine followed by a Fellowship in Endocrinology, Diabetes, and Metabolism at the Johns Hopkins University School of Medicine. She is an experienced clinician and is assisting in the recruitment and study of PCOS cases and controls.
Ron Do, PhD, is an Assistant Professor, Department of Genetics and Genomic Sciences at Icahn School of Medicine at Mount Sinai. His research focuses on the genetic and biological bases of coronary artery disease and cardiometabolic risk factors. He has formal training in human genetics, statistical genetics and population genetics. Dr. Do has expertise in human genetics, genetic epidemiology, statistical genetics, population genetics and analysis of large-scale sequencing and genotyping datasets. He plays a critical role in prioritization of the PCOS susceptibility loci to be sequenced, the design of the sequencing analysis, and selection of variants for genotyping and the review of all data analyses.
Dori Arad, PhD, RDN, CDN, CDE, EP-C, is a research associate in the Division of Endocrinology, Diabetes and Bone Disease. Dr. Arad has an expertise in nutrition, physiology, and metabolism and his research focus on obesity and diabetes. Specifically, assessing metabolic function in individuals with and at risk for type 2 diabetes. Under the guidance of Dr. Dunaif, Dr. Arad is organizing the clinical part of the Multiethnic Fine Mapping of Polycystic Ovary Syndrome study.
Alina Rahimova, MD, MS , is a Bioinformatician in the Division of Endocrinology, Diabetes and Bone Diseases at Icahn School of Medicine at Mount Sinai. Dr. Rahimova is an Endocrinologist with 8 years of experience both in clinical and research fields,with particular interest in Pediatric Endocrinology. She started her career in Biomedical Informatics after graduating from NYU School of Medicine’s Sackler Institute of Graduate Biomedical Sciences. Under supervision of Dr. Dunaif in the PCOS study, she manages and integrates knowledge from prior experiments and biological databases through existing and novel algorithms (Machine Learning, NLP).