Allergy and Immunology Research

Research Opportunities/Clinical Trials (more details available on request)

 

  • Primary Immune Deficiency
  • Newborn screen for SCID and T cell defects
  • B and T cell growth and differentiation
  • Control mechanisms of immunoglobulin production
  • Mucosal immunology
  • B cell activation by TLR agonists
  • Genetic causes of antibody deficiencies by whole exome sequencing
  • Building a Registry of Patients with Primary Immune Deficiency (USIDNET)
  • Development of memory B cells in CVID
  • Role of IgA in mucosal Immunity
  • Role of serum IgM
  • Computer targeting methods to identify immunodeficiencies in minorities
  • Immunomodulators in immune dysregulation diseases
  • Multi-omic analyses of immune diseases
  • Computer analysis of immune deficiency states
  • Novel treatments for hereditary angioedema (HAE)
  • Development of a quality of life instrument for patients with HAE
  • Role of estrogen in bradykinin production and degradation
  • Treatment of chronic spontaneous urticarial with biologics
  • Bioinformatics of allergic diseases
  • Effect of depression on aging and asthma
  • Evaluation of airway inflammation in WTC-induced asthma
  • Effect of cockroach immunotherapy on asthma control in children
  • Environmental epigenetics and asthma, allergy, breast cancer risk
  • Air pollution exposure and asthma
  • Chemical (phthalates, pesticides, bisphenol A) exposure and asthma
  • Mitochondrial DNA biomarkers to assess responses to changes in personal environmental exposures in pediatric urban asthma
  • Children’s Respiratory Research Workgroup (CREW) national consortium
  • Anaphylaxis
  • Food protein induced enterocolitis syndrome (FPIES)
  • Eosinophilic esophagitis
  • Novel therapies for food allergy-oral immunotherapy, epicutaneous, biologics
  • Allergen characterization – B cell epitopes
  • Antigen-presenting cells in food allergy
  • T cell immunophenotypic changes secondary to immunotherapy in food allergy
  • Basophil activation assays
  • Murine models of food allergy and immunotherapy