Allergy and Immunology Research

To read more about the ongoing basic science and clinical research in the Division of Clinical Immunology, please click here.

To read more about the ongoing basic science and clinical research in the Elliot and Roslyn Jaffe Food Allergy Institute, please click here.

Research Opportunities/Clinical Trials (more details available on request)

 

  • Primary Immune Deficiency
  • Newborn screen for SCID and T cell defects
  • B and T cell growth and differentiation
  • Control mechanisms of immunoglobulin production
  • Mucosal immunology
  • B cell activation by TLR agonists
  • Genetic causes of antibody deficiencies by whole exome sequencing
  • Building a Registry of Patients with Primary Immune Deficiency (USIDNET)
  • Development of memory B cells in CVID
  • Role of IgA in mucosal Immunity
  • Role of serum IgM
  • Computer targeting methods to identify immunodeficiencies in minorities
  • Immunomodulators in immune dysregulation diseases
  • Multi-omic analyses of immune diseases
  • Computer analysis of immune deficiency states
  • Novel treatments for hereditary angioedema (HAE)
  • Development of a quality of life instrument for patients with HAE
  • Role of estrogen in bradykinin production and degradation
  • Treatment of chronic spontaneous urticarial with biologics
  • Bioinformatics of allergic diseases
  • Effect of depression on aging and asthma
  • Evaluation of airway inflammation in WTC-induced asthma
  • Effect of cockroach immunotherapy on asthma control in children
  • Environmental epigenetics and asthma, allergy, breast cancer risk
  • Air pollution exposure and asthma
  • Chemical (phthalates, pesticides, bisphenol A) exposure and asthma
  • Mitochondrial DNA biomarkers to assess responses to changes in personal environmental exposures in pediatric urban asthma
  • Children’s Respiratory Research Workgroup (CREW) national consortium
  • Anaphylaxis
  • Food protein induced enterocolitis syndrome (FPIES)
  • Eosinophilic esophagitis
  • Novel therapies for food allergy-oral immunotherapy, epicutaneous, biologics
  • Allergen characterization – B cell epitopes
  • Antigen-presenting cells in food allergy
  • T cell immunophenotypic changes secondary to immunotherapy in food allergy
  • Basophil activation assays
  • Murine models of food allergy and immunotherapy

Click here to see a list of publications by our current and past fellows.