Allergy and Immunology Research
Research Opportunities/Clinical Trials (more details available on request)
- Primary Immune Deficiency
- Newborn screen for SCID and T cell defects
- B and T cell growth and differentiation
- Control mechanisms of immunoglobulin production
- Mucosal immunology
- B cell activation by TLR agonists
- Genetic causes of antibody deficiencies by whole exome sequencing
- Building a Registry of Patients with Primary Immune Deficiency (USIDNET)
- Development of memory B cells in CVID
- Role of IgA in mucosal Immunity
- Role of serum IgM
- Computer targeting methods to identify immunodeficiencies in minorities
- Immunomodulators in immune dysregulation diseases
- Multi-omic analyses of immune diseases
- Computer analysis of immune deficiency states
- Novel treatments for hereditary angioedema (HAE)
- Development of a quality of life instrument for patients with HAE
- Role of estrogen in bradykinin production and degradation
- Treatment of chronic spontaneous urticarial with biologics
- Bioinformatics of allergic diseases
- Effect of depression on aging and asthma
- Evaluation of airway inflammation in WTC-induced asthma
- Effect of cockroach immunotherapy on asthma control in children
- Environmental epigenetics and asthma, allergy, breast cancer risk
- Air pollution exposure and asthma
- Chemical (phthalates, pesticides, bisphenol A) exposure and asthma
- Mitochondrial DNA biomarkers to assess responses to changes in personal environmental exposures in pediatric urban asthma
- Children’s Respiratory Research Workgroup (CREW) national consortium
- Anaphylaxis
- Food protein induced enterocolitis syndrome (FPIES)
- Eosinophilic esophagitis
- Novel therapies for food allergy-oral immunotherapy, epicutaneous, biologics
- Allergen characterization – B cell epitopes
- Antigen-presenting cells in food allergy
- T cell immunophenotypic changes secondary to immunotherapy in food allergy
- Basophil activation assays
- Murine models of food allergy and immunotherapy