At the Black Family Stem Cell Institute, we are committed to understanding the mechanisms that govern embryonic stem cells, how they develop in a normal embryo, and how embryonic stem cells determine their “fate” or functions.
In addition, we study adult stem cells and how they develop. Adult stem cells are essential for the replacement of cells with finite life span and for maintaining healthy tissues. Adult stem cells are found in the bone marrow as hematopoietic stem cells that give rise to all blood cells, in the skin and intestine, and in many other tissues, including the liver, skeletal muscle, and the brain.
By integrating the biology of embryonic and adult stem cells, scientists will focus on building and/or expanding expertise in a number of different areas, including the hematopoietic, cardiac, skeletal muscle, and pancreatic systems. The Icahn School of Medicine at Mount Sinai is in a strong position to develop a broad stem cell program with existing strengths and expertise in various stem cell research areas, as well as expertise in bone marrow, liver, and kidney transplantation.