We house all animals in accordance with the USDA and/or recommendations of the Public Health Service and/or Guide for the Care and Use of Laboratory Animals, 1996. All animal housing rooms are heated and air-conditioned. Below, we outline our specifications by types of animals:
Ferrets: We house these animals in isolation units designed to provide protection from cross contamination. We set up all units for negative pressure operation and supply water and food daily in bowls. Each isolation cubicle houses three to four ferrets and is made of thermoset plastic with polycarbonate doors and removable stainless steel floors fitted with easily removable waste pans accessed through a trap door for cleaning.
Rodents: We house all rodents in individually-ventilated polysulfone rodent cages. We supply ventilation via a HEPA-filtered supply, wall-mounted unit. Exhaust is connected to the building’s exhaust fans with a flexible hose assembly. Each rack unit holds 140 mouse cages or 35 rat cages. Each unit has automatic watering manifolds and we filter the water using reverse osmosis at the Icahn and Hess buildings, or autochannel at the Annenberg building. The food is irradiated (Purina Pico #5053). Cages with weaning mice or special studies use water bottles. We house all other rodents in the Atran building in solid-bottom polycarbonate rodent cages. Water is provided through water bottles, and food is standard rodent chow (Purina chow #5001). Breeder chow is available (Purina Pico #5058).
Rabbits: We house rabbits socially, in stainless steel wire floored units with much of the function automated. Pans are automatic flushing and water is supplied automatically. We supply food through an intra-cage J-feeder.
Guinea pigs: These animals live in large polypropylene cages with contact bedding. We have three to five guinea pigs in a cage. They receive water in water bottles and food comes ad libitum in a J-feeder.
Sheep: We house sheep, five or six to a room, in a free-range style room with pine shavings covering the floor. We spot clean the pine shavings daily and fully replace them once a week. Sheep receive water and food in bowls every day. When instructions require us to withhold oral intake of food, we isolate the sheep in a cage within the room.
Swine: We house pigs in social kennels. The vendor provides compatibility data to allow pair housing. Watering is automatic and we provide food in metal J-feeders, for all pigs, including post-operative ones. We give the pigs large rubber balls for expression of rooting behavior. We typically house postoperative pigs in kennels on casters with vinyl-coated perforated metal flooring.
Nonhuman primates: We house nonhuman primates in one-over-one stainless steel squeeze back units. We use two types of units. One has three solid sides and an open door region; we are phasing this type of unit out, though it currently accounts for half of the available cages. The second type of unit has three open sides and one removable side or bottom to make one large cage. We design these units to promote social housing and socialization of species. We supply water through automatic watering, and provide food biscuits ad libitum or based upon caloric calculations.