The Institute for Exposomic Research

Publications and Media

Faculty members in the Institute for Exposomic Research regularly publish novel findings that demonstrate how early environmental exposures affect health, disease, and development throughout the lifespan. Our publications and work have been highlighted in prestigious journals and in the press. Our highlighted publications and media feature research by Institute faculty in the field of exposomics.

Early-life Dentine Manganese Concentrations and Intrinsic Functional Brain Connectivity in Adolescents: A Pilot Study
Erik de Water , Demetrios M. Papazaharias, Claudia Ambrosi, Lorella Mascaro, Emilia Iannilli, Roberto Gasparotti, Roberto G. Lucchini, Christine Austin, Manish Arora, Cheuk Y. Tang, Donald R. Smith, Robert O. Wright, Megan K. Horton
August 14, 2019

Fluoride Exposure and Kidney and Liver Function Among Adolescents in the United States: NHANES, 2013 – 2016
Ashley J.Malin, Corina Lesseur, Stefanie A. Busgang, Paul Curtin, Robert O. Wright, Alison P. Sanders
August 8, 2019

Elemental Signatures of Australopithecus Africanus Teeth Reveal Seasonal Dietary Stress
Renaud Joannes-Boyau, Justin W. Adams, Christine Austin, Manish Arora, Ian Moffat, Andy I. R. Herries, Matthew P. Tonge, Stefano Benazzi, Alistair R. Evans, Ottmar Kullmer, Stephen Wroe, Anthony Dosseto & Luca Fiorenza
July 15, 2019

Metabolomics of Neonatal Blood Spots Reveal Distinct Phenotypes of Pediatric Acute Lymphoblastic Leukemia and Potential Effects of Early-life Nutrition
Lauren M.Petrick, Courtney Schiffman, William M.B. Edmands, Yukiko Yano, Kelsi Perttula, Todd Whitehead, Catherine Metayer, Craig E. Wheelock, Manish Arora, Hasmik Grigoryan, Henrik Carlsson, Sandrine Dudoit, Stephen M.Rappaport
Jun 28, 2019

Modeling and Surveillance of Reporting Delays of Mosquitoes and Humans Infected with West Nile Virus and Associations with Accuracy of West Nile Virus Forecasts
Nicholas B. DeFelice, Ruthie Birger, Nathaniel DeFelice
April 26, 2019

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Prenatal and Early Postnatal Exposure to Manganese Could Affect Cognitive Ability and Motor Control in Teens — August 14, 2019
Mount Sinai researchers discover that early-life exposure to the mineral manganese disrupts the way different areas of the brain involved in cognitive ability and motor control connect in teenagers. This study is the first to link evidence of metal exposure found in baby teeth to measures of brain connectivity.

Fluoride May Diminish Kidney and Liver Function in Adolescents, Study Suggests — August 8, 2019
A study conducted by Mount Sinai researchers found that fluoride exposure may lead to a reduction in kidney and liver function among adolescents in the United States, where 74 percent of public water systems add fluoride for dental health benefits. The findings also suggest that adolescents with poorer kidney or liver function may absorb more fluoride in their bodies.

Early Human Species' Teeth Provide Insight Into Evolution of Breastfeeding — July 15, 2019
Mount Sinai researchers working as part of an international team have discovered previously unknown breastfeeding patterns of an extinct early human species by studying their 2-million-year-old teeth, providing insights into the evolution of human breastfeeding practices. "Seeing how breastfeeding has evolved over time can inform best practices for modern humans by bringing in evolutionary medicine," said one of the study's first authors, Christine Austin, PhD, Assistant Professor of Environmental Medicine and Public Health at Mount Sinai.

Mount Sinai Scientist Awarded $8 Million for Visionary Research on Environmental Influences on Health and Disease — June 4, 2019
Manish Arora, PhD, Professor, Environmental Medicine and Public Health at Mount Sinai, has been awarded $8 million to conduct research surrounding the Biodynamic Interface theory. Dr. Arora and his team will use this award to combine the theory with newly developed technology to develop predictive models that may prevent diseases decades before any clinical signs are apparent. 

$43 Million Grant for Study of Environmental Effects of Children's Health — November 5, 2018
Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $43 million grant from the National Institutes of Health (NIH) to continue their work in a sweeping five-year research program called Environmental influences on Child Health Outcomes (ECHO).

Researchers Discover Earliest Recorded Lead Exposure in 250,000 Year-Old Neanderthal Teeth — October 31, 2018
Using evidence found in teeth from two Neanderthals from southeastern France, researchers from the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai report the earliest evidence of lead exposure in an extinct human-like species from 250,000 years ago.

Prenatal Exposure to Phthalates Significantly Associated with Elevated Rate of Language Delay in Children in Sweden and the U.S. — October 29, 2018
In the first study of its kind, researchers from the Icahn School of Medicine at Mount Sinai and Karlstad University in Sweden have found an elevated rate of language delay in children at 30 months old who were born to mothers exposed to phthalates, synthetic chemicals found in common household items and personal care products.

Mount Sinai Exposomics Leader Named to the National Advisory Environmental Health Sciences Council — September 10, 2018
Robert Wright, MD, MPH, Ethel H. Wise Professor and Chair of the Department of Environmental Medicine and Public Health, and Director of the Institute for Exposomic Research, at the Icahn School of Medicine at Mount Sinai, has been appointed by U.S. Secretary of Health and Human Services Alex Azar to serve on the National Advisory Environmental Health Sciences Council.

Zinc and Copper Metabolic Cycles in Baby Teeth Linked to Autism — May 30, 2018
Mount Sinai research could result in early diagnostic system for autism spectrum disorder.

National $8.5 Million Grant Awarded to Mount Sinai Institute for Exposomics Research — May 7, 2018
Five-year award will continue research on early environmental exposures and its effects on health and development.

Mount Sinai Receives $100,000 from The Honest Company for Inaugural Children’s Environmental Health Innovation Grant — March 21, 2018
Grant will support two postdoctoral fellows’ research on how environment influences health throughout life.

Exposure to Specific Toxins and Nutrients During Late Pregnancy and Early Life Correlated With Autism Risk — June 1, 2017
Mount Sinai study uses a unique source—baby teeth—to reveal that both the timing and amount of exposure can affect diagnosis.

Wild Orangutan Teeth Provide Insight Into Human Breast-feeding Evolution — May 17, 2017
Biomarkers in the teeth of wild orangutans show nursing patterns, shedding insight on breast-feeding evolution in humans.

This Common Mineral May Damage Teen Brains: Study
New York Post – August 14, 2019
Mount Sinai researchers found that childhood exposure to the mineral manganese can potentially impact their motor control and brain function – specifically, memory.

Fluoride May Diminish Kidney and Liver Function in Adolescents, Study Suggests
Medical Xpress – August 8, 2019
Study suggests that fluoride exposure may lead to a reduction to kidney and liver function in adolescents.

Diabetes Risk Tied to Common Chemicals, Curbed by Healthy Habits
Business Insider – August 8, 2019
A study suggests that chemicals in everything from food wrappers to clothing and furniture are associated with an increased risk of diabetes, but much of this added risk is reduced with good eating and exercise habits.

Metabolites Linked to Nutrition May Play a Role in Childhood Leukemia Risk
NIEHS Environmental Factor – August, 2019
NIEHS grantees revealed associations between the presence of certain metabolites shortly after birth and childhood diagnosis of acute lymphoblastic leukemia (ALL).

How to Talk to Tweens About Body Odor (Without Making it Awkward)
The Washington Post – July 25, 2019
Dr. Luz Claudio, Professor of children’s environmental medicine and public health at Mount Sinai provides guidance on how to have the hygiene talk with tweens. 

Early Humans Breastfed Their Young for a Year, Study Says
CNN – July 15, 2019
Seeing how breastfeeding has evolved over time can inform best practices for modern humans by bringing in evolutionary medicine. 

Is Your Mattress Releasing Toxins While You Sleep?
HealthDay – July 10, 2019
Research suggests that body heat may trigger the release of potentially harmful chemicals from your mattress.

Chemicals in Soaps, Hand Sanitizers Tied to Osteoporosis
Reuters – June 26, 2019
Women exposed to triclosan, a chemical often found in soaps and hand sanitizers, may be more likely to develop osteoporosis than women who have not been exposed.

US Playgrounds: Fears Grow Over Health Risks from Rubber Particles
The Guardian – June 25, 2019
Thousands of playgrounds and sports fields across the United States have been covered with crumb rubber from recycled tires, and some experts and lawmakers are concerned about the possible health effects on children.

Mount Sinai Scientist Awarded $8 Million for Visionary Research on Environmental Influences on Health and Disease
Yahoo! Finance – June 5, 2019
A theory that proposes the existence of a dynamic interface between the environment and human physiology over someone's lifetime has earned leading Mount Sinai researcher, Dr. Manish Arora, the prestigious Outstanding Investigator Award from the National Institute of Environmental Health Sciences (NIEHS)

Why Science Needs Community Engagement
Ted – May 6, 2019
Dr. Luz Claudio gives a Ted Talk on a collaborate approach to science called Community-based Participatory Research (CBPR), a scientific method that engages community members, interns, and health professionals to achieve common goals.

The Scale of Climate Change Can Feel Scary, So We Asked 5 Climate Scientists to Break it Down
Bustle – April 24, 2019
Dr. Luz Claudio discusses air pollution and its effect on vulnerable populations, such as children.

How to Minimize Exposures to Hormone Disrupters
The New York Times – April 1, 2019
Experts discuss how avoiding canned goods and certain plastics and using natural cleaning products can minimize hormone disruptor exposure for adults and children alike.

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