A full list of publications is available here.

Most recent publications:


Reduced neural encoding of utility prediction errors in cocaine addiction. Neuron 2023. Anna B Konova, Ahmet O. Ceceli, Guillermo Horga, Scott J. Moeller, Nelly Alia-Klein, Rita Z. Goldstein.

Whole-brain resting-state connectivity underlying impaired inhibitory control during early versus longer-term abstinence in cocaine addiction. Molecular Psychiatry 2023. Anna Zilverstand, Muhammad A. Parvaz, Scott J. Moeller, Selim Kalayci, Prantik Kundu, Pias Malaker, Nelly Alia-Klein, Zeynep H. Gümüş, Rita Z. Goldstein.

Emotional Expression on Social Media Support Forums for Substance Cessation: Observational Study of Text-Based Reddit Posts. Journal of Medical Internet Research 2023. Genevieve Yang, Sarah G. King, Hung-Mo Lin, and Rita Z Goldstein.

Association of Cortico-Striatal Engagement During Cue Reactivity, Reappraisal, and Savoring of Drug and Non-Drug Stimuli with Craving in Heroin Addiction. American Journal of Psychiatry 2023. Yuefeng Huang, Ahmet O. Ceceli, Greg Kronberg, Sarah King, Pias Malaker, Muhammad A. Parvaz, Nelly Alia-Klein, Eric L. Garland, Rita Z. Goldstein.

Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis. Neuropsychopharmacology 2023. Eduardo R. Butelman, Yuefeng Huang, David H. Epstein, Yavin Shaham, Rita Z. Goldstein, Nora D. Volkow, Nelly Alia-Klein.

Common and distinct fronto-striatal volumetric changes in cocaine and heroin use disorderBrain 2023. Ahmet O. Ceceli, Yuefeng Huang, Greg Kronberg, Pias Malaker, Pazia Miller, Pierre-Olivier Gaudreault, Natalie McClain, Lily Gabay, Devarshi Vasa, Jeffrey H. Newcorn, Defne Ekin, Nelly Alia-Klein, Rita Z. Goldstein.

Altered prefrontal signaling during inhibitory control in a salient drug context in cocaine use disorder. Cerebral Cortex 2023. Ahmet O. Ceceli, Muhammad A. Parvaz, Sarah King, Matthew Schafer, Pias Malaker, Akarsh Sharma, Nelly Alia-Klein, Rita Z Goldstein.

An fMRI marker of drug and food craving. Nature Neuroscience 2023. Gregory Kronberg and Rita Z. Goldstein.

The neural signature of impaired inhibitory control in individuals with heroin use disorder. Journal of Neuroscience 2023. Ahmet O. Ceceli, Sarah G. King, Natalie McClain, Nelly Alia-Klein, Rita Z. Goldstein.


Prefrontal-habenular microstructural impairments in human cocaine and heroin addiction. Neuron 2022. Sarah G. King, Pierre-Olivier Gaudreault, Pias Malaker, Joo-Won Kim, Nelly Alia-Klein, Junqian Xu, Rita Z. Goldstein.  

Whole-brain white matter abnormalities in human cocaine and heroin use disorders: association with craving, recency, and cumulative use. Molecular Psychiatry 2022. Pierre-Olivier Gaudreault, Sarah G. King, Pias Malaker, Nelly Alia-Klein, Rita Z. Goldstein.

Neuropsychoimaging Measures as Alternatives to Drug Use Outcomes in Clinical Trials for Addiction. JAMA Psychiatry 2022. Rita Z. Goldstein.

Emotion recognition in individuals with cocaine use disorder: the role of abstinence length and the social brain network. Psychopharmacology (Berl) 2022. Rachel A. Rabin, Muhammad A. Parvaz, Nelly Alia-Klein, Rita Z. Goldstein.

A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus. Nature Protocols 2022. Hamed Ekhtiari, Mehran Zare-Bidoky, Arshiya Sangchooli, …Rita Z. Goldstein, … Kai Yuan, Xiaochu Zhang, and Anna Zilverstand.

Common and gender-specific associations with cocaine use on gray matter volume: Data from the ENIGMA addiction working group. Human Brain Mapping 2022. Rachel A. Rabin, Scott Mackey, Muhammad A. Parvaz, Janna Cousijn, Chiang‐shan Li, Godfrey Pearlson, Lianne Schmaal, Rajita Sinha, Elliot Stein, Dick Veltman, Paul M. Thompson, Patricia Conrod, Hugh Garavan, Nelly Alia‐Klein, and Rita Z. Goldstein.

White matter microstructure differences in individuals with dependence on cocaine, methamphetamine and nicotine: Findings from the ENIGMA-Addiction Working Group. Drug and Alcohol Dependence 2022. Jonatan Ottino-González, Anne Uhlmann, Sage Hahn, Zhipeng Cao, … Rita Z Goldstein, …Conrod, Scott Mackey, Hugh Garavan.

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex. Neuropsychopharmaology: Annual Reviews 2022. Ahmet Ceceli, Charles W. Bradberry, Rita Z. Goldstein. Recommended in Faculty Opinions as being of special significance in its field.


A double-blind sham-controlled phase 1 clinical trial of tDCS of the dorsolateral prefrontal cortex in cocaine inpatients: Craving, sleepiness, and contemplation to change. The European journal of neuroscience 2021. Pierre-Olivier Gaudreault, Akarsh Sharma, Abhishek Datta, Ester M. Nakamura-Palacios, Sarah King, Pias Malaker, Ariella Wagner, Devarshi Vasa, Muhammad A. Parvaz, Lucas C. Parra, Nelly Alia-Klein, Rita Z. Goldstein.

Attention bias modification in drug addiction: Enhancing control of subsequent habits. PNAS 2021. Muhammad A. Parvaz, Pias Malaker, Anna Zilverstand, Scott J. Moeller, Nelly Alia-Klein, and Rita Z. Goldstein.

Featured publications:

Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. The American journal of psychiatry 2002. Rita Z Goldstein and Nora D. Volkow.

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nature Review Neuroscience 2011. Rita Z Goldstein and Nora D Volkow.

Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiology of Learning and Memory 2002. Nora D. Volkow, Joanna S. Fowler, Gene-Jack Wang, Rita Z. Goldstein.

The neurocircuitry of impaired insight in drug addiction. Trends in cognitive sciences 2009. Rita Z. Goldstein, A.D. Bud Craig, Antoine Bechara, Hugh Garavan, Anna Rose Childress, Martin P. Paulus, Nora D. Volkow.

High levels of dopamine D2 receptors in unaffected members of alcoholic families. Archives of general psychiatry 2006. Nora D. Volkow, Gene-Jack Wang, Henri Begleiter, Bernice Porjesz, Joanna S. Fowler, Frank Telang, Christopher Wong, Yeming Ma, Jean Logan, Rita Goldstein, David Alexoff, Peter K. Thanos.

Incubation of cue-induced craving in adults addicted to cocaine measured by electroencephalography. JAMA Psychiatry 2016. Muhammad A. Parvaz, Scott J. Moeller, Rita Z. Goldstein.

Anterior cingulate cortex hypoactivations to an emotionally salient task in cocaine addiction. PNAS 2009. Rita Z. Goldstein, Nelly Alia-Klein, Dardo Tomasi, Jean Honorio Carrillo, Thomas Maloney, Patricia A. Woicik, Ruiliang Wang, Frank Telang, Nora D. Volkow.

Oral methylphenidate normalizes cingulate activity in cocaine addiction during a salient cognitive task. PNAS 2010. Rita Z. Goldstein, Patricia A. Woicik, Thomas Maloney, Dardo Tomasi, Nelly Alia-Klein, Juntian Shan, Jean Honorio, Dimitris Samaras, Ruiliang Wang, Frank Telang, Gene-Jack Wang, Nora D. Volkow.

Attention bias modification in drug addiction: Enhancing control of subsequent habits. PNAS 2021. Muhammad A. Parvaz, Pias Malaker, Anna Zilverstand, Scott J. Moeller, Nelly Alia-Klein, and Rita Z. Goldstein.

Human Cognitive Ability Is Modulated by Aromatase Availability in the Brain in a Sex-Specific Manner. Frontiers in Neuroscience 2020. Nelly Alia-Klein, Rebecca N. Preston-Campbell, Sun Won Kim, Deborah Pareto, Jean Logan, Gene-Jack Wang, Scott J. Moeller, Joanna S. Fowler, Anat Biegon.

The feeling of anger: From brain networks to linguistic expressions. Neuroscience and biobehavioral reviews 2020. Nelly Alia-Klein, Gabriela Gan, Gadi Gilam, Jessica Bezek, Antonio Bruno, Thomas F. Denson, Talma Hendler, Leroy Lowe, Veronica Mariotti, Maria R. Muscatello, Sara Palumbo, Silvia Pellegrini, Pietro Pietrini, Amelia Rizzo, Edelyn Verona.

Habenula-prefrontal resting-state connectivity in reactive aggressive men - A pilot study. Neuropharmacology 2019. G. Gan, A. Zilverstand, M.A. Parvaz, R.N. Preston-Campbell, F. d’Oleire Uquillas, S.J. Moeller, D.Tomasi, R.Z.Goldstein, N. Alia-Klein.

Neuroimaging Impaired Response Inhibition and Salience Attribution in Human Drug Addiction: A Systematic Review. Neuron 2018. Anna Zilverstand, Anna S. Huang, Nelly Alia-Klein, Rita Z. Goldstein.

Reactions to Media Violence: It’s in the Brain of the Beholder. PLoS one 2014. Nelly Alia-Klein, Gene-Jack Wang, Rebecca N. Preston-Campbell, Scott J. Moeller, Muhammad A. Parvaz, Wei Zhu, Millard C. Jayne, Chris Wong, Dardo Tomasi, Rita Z. Goldstein, Joanna S. Fowler, Nora D. Volkow.

Gene x disease interaction on orbitofrontal gray matter in cocaine addiction. Archives of general psychiatry 2011. Nelly Alia-Klein, Muhammad A. Parvaz, Patricia A. Woicik, Anna B. Konova, Thomas Maloney, Elena Shumay, Ruiliang Wang, Frank Telang, Anat Biegon, Gene-Jack Wang, Joanna S. Fowler, Dardo Tomasi, Nora D. Volkow, Rita Z. Goldstein.