The 1940's to the 1950's marked the start of the Endocrine Division, the Endocrine Clinic, the publication of Diseases of the Endocrine Glands, the earliest use of ACTH therapeutically, the start of the Fellowship Program, and an elective program in Endocrinology and the introduction of I-131 in the treatment of thyroid disease at The Mount Sinai Hospital.
Mount Sinai opened the first pre-natal diabetes clinic in NYC.
Solomon Berson and Rosalyn Yalow published a definitive paper on the quantitation of the reaction between antigen and antibody in which they noted the conditions necessary for the performance of immunoassay. This allowed scientists to determine the amount of insulin and all other peptide hormones in the blood or other body fluids and tissues. Berson was later named Chair of Mount Sinai’s Department of Medicine.
Mount Sinai’s Rosalyn Yalow, PhD won the Nobel Prize for the development of radioimmunoassay (RIA).
Mount Sinai’s Eng discovered a new compound that kept the body’s blood sugar at a steady, normal level helping diabetic patients prevent conditions such as blindness, kidney failure and nerve damage.
Mount Sinai’s Poplawski, Mastaitis, Isoda, Grosjean, Zheng and Mobbs demonstrated that diabetic nephropathy can be reversed by a relatively simple dietary intervention of adopting a ketogenic diet.
Mount Sinai’s Baliram, Latif, Berkowitz, Frid, Colaianni, Sun, Zaidi and Davies found that thyroid-stimulating hormone can promote bone growth independent of its usual thyroid functions.