The physicians and scientists in the Department of Medicine are continuously making discoveries and providing insights that have a significant impact on science, medicine and, ultimately, people’ lives. Their research and medical expertise are recognized in prestigious academic journals as well as the mainstream press and social media outlets. The Department of Medicine has multiple platforms to highlight and share their medical breakthroughs, advice and recommendations.
Please read some of DOM’s latest academic research publications:
Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse, by David Volsky, et al., ACS Chemical Neuroscience
Plasma biomarkers are associated with renal outcomes in individuals with APOL1 risk variants, by Girish Nadkarni, Erwin Bottinger, Steve Coca, et al., Kidney International.
Low-dose valganciclovir for cytomegalovirus prophylaxis in intermediate-risk liver transplantation recipients, by Timothy Sullivan, Dallas Dunn, Gopi Patel, Shirish Huprikar, et al., Liver Transplantation
Profile of apalutamide in the treatment of metastatic castration-resistant prostate cancer: Evidence to date (Review) by William Oh, et al., OncoTargets and Therapy
The prognostic importance of duration of AKI: A systematic review and meta-analysis (Review), by Girish Nadkarni, Steve Coca, et al., BMC Nephrology
When Do You Start and When Do You Stop Screening for Colon Cancer in Inflammatory Bowel Disease?, by Bruce Sands, et al., Clinical Gastroenterology and Hepatology
What Is the Role of the Inflammatory Bowel Disease Panel in Diagnosis and Treatment?, by Bruce Sands, et al., Clinical Gastroenterology and Hepatology
Understanding the tumor immune microenvironment (TIME) for effective therapy, by Meriam Merad, et al., Nature Medicine
Urbanization and the gut microbiota in health and inflammatory bowel disease, by Jean-Frederic Colombel, et al., Nature Reviews Gastroenterology and Hepatology.
Dual paraneoplastic endocrine syndromes heralding onset of extrapulmonary small cell carcinoma: A case report and narrative review, by Jill Feffer, Natalia Branis, Jeanine Albu, Frontiers in Endocrinology
Associations of Residential Socioeconomic, Food, and Built Environments with Glycemic Control in Persons with Diabetes in New York City from 2007-2013, by Carol Horowitz, Victoria Mayer, et al., American Journal of Epidemiology
Hyperinsulinemia promotes esophageal cancer development in a surgically-induced duodeno-esophageal reflux murine model, by Emily Gallagher, Derek LeRoith, et al., International Journal of Molecular Sciences
Noninvasive prediction of portal pressure with MR elastography and DCE-MRI of the liver and spleen: Preliminary results, by Thomas Schiano, et al., Journal of Magnetic Resonance Imaging
The prevalence and significance of Staphylococcus aureus in patients with non-cystic fibrosis bronchiectasis, by Edward Eden, Gerald Turino, et al., Annals of the American Thoracic Society
Pathway for the management of hyperglycemia in the cardiac care unit, by Jeanine Albu, Eyal Herzog, Seyed Dehkordi, et al., Critical Pathways in Cardiology
Feasibility and safety of microforceps biopsy in the diagnosis of pancreatic cysts, by Christopher DiMaio, et al., Gastrointestinal Endoscopy
Efficacy and Safety of Digital Single-Operator Cholangioscopy for Difficult Biliary Stones, by Christopher DiMaio, Nikhil Kumta, et al., Clinical Gastroenterology and Hepatology.
Adverse drug events and medication problems in “Hospital at Home” patients, by Alex Federman, et al., Home Health Care Services Quarterly
Right Care in Hospital Medicine: Co-creation of Ten Opportunities in Overuse and Underuse for Improving Value in Hospital Medicine, by Harry Cho, Surafel Tsega, et al., Journal of General Internal Medicine
Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice, by David Volsky, Mary Jane Potash, et al., Journal of NeuroVirology
Central nervous system histoplasmosis, by Shirish Huprikar, et al., Medicine
A Palliative Radiation Oncology Consult Service's Impact on Care of Advanced Cancer Patients, by Juan Wisnivesky, et al., Journal of Palliative Medicine
Lysosomal acid lipase deficiency allograft recurrence and liver failure- clinical outcomes of 18 liver transplantation patients, by Thomas Schiano, et al., Molecular Genetics and Metabolism
CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions, by Sergio Lira, Miriam Merad, et al., Cancer
Assessment of atherosclerotic plaque activity in patients with sleep apnea using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI): a feasibility study, by Neomi Shah, et al., Sleep and Breathing
Obstructive sleep apnea severity affects amyloid burden in cognitively normal elderly: A longitudinal study, by David Rapoport, Andrew Varga, Indu Ayappa, et al., American Journal of Respiratory and Critical Care Medicine
Targeting KCa1.1 channels with a scorpion venom peptide for the therapy of rat models of rheumatoid arthritis, by Percio Gulko, Theresa Laragione, et al., Journal of Pharmacology and Experimental Therapeutics
Cost-effectiveness of hepatitis C screening and treatment linkage intervention in US methadone maintenance treatment programs, by David Perlman, et al., Drug and Alcohol Dependence
A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma, by Augusto Villanueva, Daniela Sia, Scott Friedman, Josef Llovet, Myron Schwartz, et al., Oncogene
Analysis of biomarkers within the initial 2 years posttransplant and 5-year kidney transplant outcomes: Results from clinical trials in organ transplantation-17, by Girish Nadkarni, Madhov Menon, Barbara Murphy, Peter Heeger, et al., Transplantation
T cell expression of C5a receptor 2 augments murine regulatory T Cell (TREG) generation and TREG-dependent cardiac allograft survival, by DA Verghese, Markus Demir, Nicholas Chun, Miguel Fribourg, Paolo Cravedi, Ines Llaudo, Pradya Yadav, Sergio Lira, Madov Menon, Peter Heeger, et al., Journal of Immunology
Differences in the immune microenvironment of anal cancer precursors by HIV status and association with ablation outcomes, by Michael Gaisa, Talia Swartz, Yotam Arens, Keith Sigel, et al., Journal of Infectious Diseases
Heterogeneity in glycan composition on the surface of HIV-1 envelope determines virus sensitivity to lectins, by Muzafar Jan, Chitra Upadhyay, Caterina Hioe, et al., PLoS ONE
HIV-1 envelope glycoproteins from diverse clades differentiate antibody responses and durability among vaccines, by Susan Zolla-Pazner, et al., Journal of Virology.
Organ donor screening practices for Strongyloides stercoralis infection among US organ procurement organizations, by Shirish Huprikar, et al., Transplant Infectious Disease
Rationale and design of a randomized controlled trial of home-based primary care versus usual care for high-risk homebound older adults, by Jennifer Reckrey, Elizabeth McCormick, Linda DeCherrie, Alex Federman, et al., Contemporary Clinical Trials
A Palliative Radiation Oncology Consult Service Reduces Total Costs During Hospitalization, by Juan Wisnivesky, et al., Journal of Pain and Symptom Management
Direct-acting antiviral regimens are safe and effective in the treatment of hepatitis C in simultaneous liver–kidney transplant recipients, by James Crismale, Thomas Schiano, et al., Clinical Transplantation
ACG Clinical Guideline: Management of Crohn's Disease in Adults (review), by Bruce Sands, et al., American Journal of Gastroenterology
Biologics in allergic and immunologic diseases: Promises and challenges in the era of personalized medicine, by Mauli Desai, et al., Annals of Allergy, Asthma and Immunology
Outcomes 7 Years After Infliximab Withdrawal for Patients With Crohn's Disease in Sustained Remission, by Jean-Frederic Colombel, et al., Clinical Gastroenterology and Hepatology
Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents, by Jennifer Jao, et al., AIDS.
Is it idiopathic pulmonary fibrosis or not? (Review), by Maria Padilla, Genta Ishikawa, et al., Journal of the American Board of Family Medicine.
Characterizing hospitalist practice and perceptions of critical care delivery, by Alfred Burger, et al., Journal of Hospital Medicine
Heterogeneity in glycan composition on the surface of HIV-1 envelope determines virus sensitivity to lectins, by Chita Upadhyay, Caterina Hioe, et al., PLoS ONE.
Screening recipients of increased risk donor organs: A multicenter retrospective study, by Meenakshi Rana, et al., Transplant Infectious Disease
A Prospective Multicenter Evaluation of the Accuracy of a Novel Implanted Continuous Glucose Sensor: PRECISE II, by Carol Levy, David Lam, et al., Diabetes Technology and Therapeutics
High baseline anal human papillomavirus and abnormal anal cytology in a phase 3 trial of the quadrivalent human papillomavirus vaccine in human immunodeficiency virus-infected individuals older than 26 years: ACTG 5298, by Michelle Cesepdes, et al., Sexually Transmitted Diseases
Differences in the immune microenvironment of anal cancer precursors by HIV status and association with ablation outcomes, by Michael Gaisa, Talia Swartz, Yotam Arens, Keith Sigel, et al., Journal of Infectious Diseases
What Makes a Good Endoscopic Teacher: A Qualitative Analysis, by Brijen Shah, Kamron Pourmand, et al., Journal of Surgical Education
Genetic basis of emerging vancomycin, linezolid, and daptomycin heteroresistance in a case of persistent Enterococcus faecium bacteremia by Deena Altman, et al., Antimicrobial Agents and Chemotherapy.
The Therapeutic Potential of Hyaluronan in COPD, by Gerald Turino, Shuren Ma, Yong Lin, et al., Chest
Best Practices for Physician-Scientist Training Programs: Recommendations from the Alliance for Academic Internal Medicine, by Mone Zaidi, et al., American Journal of Medicine
Bedside assessment of the necessity of daily lab testing for patients nearing discharge, by Hyung Cho, Surafel Tsega, Colin Iberti, Michelle O’Connor, et al., Journal of Hospital Medicine
Telenephrology: Providing Healthcare to Remotely Located Patients with Chronic Kidney Disease, by Cijiang He, Anita Mehrotra, Girish Nadkarni, Eric Langhoff, James Post, et al., American Journal of Nephrology.
The Management of Intestinal Penetrating Crohn's Disease (Review), by Jean-Frederic Colombel, Robert Hirten, Shailja Shah, David Sachar, Inflammatory Bowel Diseases.
Remote Patient Monitoring in IBD: Current State and Future Directions (Review), by Ashish Atreja, Emamuzo Otobo, et al., Current Gastroenterology Reports.
Pulmonary infarction secondary to pulmonary embolism: An evolving paradigm, by David Steiger, Marjan Islam, Jason Filopei, Matthew Frank, , Navitha Ramesh, Madeline Ehrlich, Eric Bondarsky, Albert Miller, Respirology.
Benefits and Challenges of Lung Cancer Screening in Older Adults, by Juan Wisnivesky, Meytal Fabrikant, Thomas Marron, Rajwanth Veluswamy, et al. Clinical Therapeutics.
Increasing access to hepatitis C virus medications: A program model using patient navigators and specialty pharmacy to obtain prior authorization approval, by Trang Vu, Wilma Toribio, Farah Riazi, Genesis Ciprian, Nathalia Gibbs, Martha Giardina, Jocelyn Camacho, Korin Parrella, Joy Cambe, Catherine Amory, Rachel Chasen, Keith Sigel, Jeffrey Weiss, Journal of Managed Care and Specialty Pharmacy.
Palliative Care for People With Hepatocellular Carcinoma, and Specific Benefits for Older Adults, by Thomas Schiano, et al., Clincal Therapeutics.
Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma, by Sonali Bose, et al., PLoS ONE.
Step-Down Therapy for Asthma Well Controlled on Inhaled Corticosteroid and Long-Acting Beta-Agonist: A Randomized Clinical Trial, by Linda Rogers, MD, et al., Journal of Allergy and Clinical Immunology: In Practice
Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn's Disease, by Jean-Frederic Colombel, MD, et al., Gastroenterology
Heterosexual male and female disparities in HIV infection at the end of an epidemic: HIV infection among persons who inject drugs in New York City, 2001–2005 and 2011–2015, by David Perlman, MD, et al., Drug and Alcohol Dependence
Opportunistic screening for bone disease using abdominal CT scans obtained for other reasons in newly diagnosed IBD patients, by Bruce Sands, MD, et al., Osteoporosis International
Development of a novel histologic diagnostic algorithm for hepatic graft-versus-host disease, by Thomas Schiano, MD, et al., Modern Pathology
Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis, by Yujin Hoshida, MD, PhD, et al., Gastroenterology
Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses, by Andrea Cerutti, MD, et al., Immunity
Bariatric surgery is associated with increased risk of new-onset inflammatory bowel disease: Case series and national database study, by Ryan Ungaro, MD, Ashish Atreja, MD, Julia Torres, MD, Jean-Frederic Colombel, MD, et al., Alimentary Pharmacology and Therapeutics
Patients' and oncologists' views on family involvement in goals of care conversations, by Jenny Lin, MD, Cardinale Smith, MD, Nina Bickell, MD, et al., Psycho-Oncology
Evaluation of a patient-centered after visit summary in primary care, by Alex Federman, MD, Joseph Kannry, MD, et al., Patient Education and Counseling
Adherent-invasive Escherichia coli in inflammatory bowel disease (Review), by Jean-Frederic Colombel, MD, Robert Hirten, MD, et al., Gut
Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice by Jean-Frederic Colombel, MD, Ari Grinspan, MD, Jose Clemente, PhD, Meriam Merad, MD, PhD, Jerimiah Faith, PhD, et al., Gastroenterology
Brain insulin resistance in type 2 diabetes and Alzheimer disease: Concepts and conundrums (review), by Christoph Buettner, MD, PhD, Sam Gandy, MD, et al., Nature Reviews Neurology
Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment, by Satish Nagula, MD, et al., Gastrointestinal Endoscopy
Phenytoin inhibits necroptosis, by Adrien Ting, PhD, et al., Cell Death and Disease
Can an Emergency Department Observation Unit Reduce Hospital Admissions for COPD Exacerbation? by Sidney Brahman, MD, Julie Budde, MD, et al., Lung
Pilot study of living donor liver transplantation for patients with hepatocellular carcinoma exceeding Milan Criteria (Barcelona Clinic Liver Cancer extended criteria) by Josef Llovet, MD, et al., Journal of Liver Transplantation
Gonorrhea and Chlamydia Case Detection Increased When Testing Increased in a Multisite US HIV Cohort, 2004-2014 by Judith Aberg, MD, et al., Journal of Acquired Immune Deficiency Syndromes
Reassessing the safety concerns of utilizing blood donations from patients with hemochromatosis, by Adam Winter, MD, Douglas Tremblay, MD, John Mascarenhas, MD, Thomas Schiano, MD et al, in Hepatology
Long-term Outcomes of Gastroenteropancreatic Neuroendocrine Tumors, by Weiwei Chi, MD, Richard Warner, MD, Juan Wisnivesky, MD, DrPH, Michelle K. Kim, MD, PhD, in Pancreas
Practices, attitudes, and knowledge about Crohn’s disease and smoking cessation among gastroenterologists, by Benjamin Nulsen, MD, Bruce Sands, MD, MS, Brijen Shah, MD, and Ryan Ungaro, MD, in European Journal of Gastroenterology & Hepatology
Well differentiated grade 3 pancreatic neuroendocrine tumors compared with related neoplasms: A morphologic study, by Keith Sigel, MD, et al, Cancer Cytopathology
Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma, by Paula J. Busse, MD, et al, Frontiers in Immunology
Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector TH2 subsets, Miriam Merad, MD, PhD, et al, Journal of Allergy and Clinical Immunology
Histological assessment of the liver explant in transplanted hepatitis C virus patients achieving sustained virological response with direct-acting antiviral agents, by Thomas Schiano, MD, et al, Histopathology
A case of late-onset cytomegalovirus myocarditis in an orthotopic heart transplant recipient; case report and review of the literature, by Ruben Mylvaganam, MD, Alison Glaser, MD, Noah Moss, MD and Meena Rana, MD, Diagnostic Microbiology and Infectious Disease
Genomic analysis revealed new oncogenic signatures in TP53-mutant hepatocellular carcinoma, Yujin Hoshida, MD, PhD, Frontiers in Genetics
Location-Specific Oral Microbiome Possesses Features Associated With CKD, Steven Coca, DO and Girish N. Nadkarni, MD, et al, Kidney International Reports
Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID), by Charlotte Cunningham-Rundles, MD, PhD, et al, Journal of Clinical Immunology
Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury, by Peter Chuang, MD, Cijiang He, MD, PhD, Kidney International
Tuberculosis after liver transplantation in a large center in New York City: QuantiFERON®-TB Gold-based pre-transplant screening performance and active tuberculosis post-transplant, by Keith Sigel, MD, Shrish Huprikar, MD, and Meena Rana, MD, et al, Transplant Infectious Disease
Cough Due to TB and Other Chronic Infections: CHEST Guideline and Expert Panel Report by Sidney Braman, MD, et al, Chest
Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice, by Miriam Merad, MD, PhD, et al, Nature Communications
The impact of donor liver allograft fibrosis on patients undergoing liver transplantation, by Thomas Schiano, MD, et al, Clinical Transplantation
Hippo pathway deficiency and recovery from heart failure after myocardial infarction: potential implications for kidney disease, by Kristen Meliambro, MD, Kirk Campbell, MD, Kidney International
The Impact of Partnership Status on Diabetes Control and Self-Management Behaviors, by Juan Wisnivesky, MD, DrPH, Lindsay Haines, MD, Natalie Coppa, BA, et al, Health Education & Behavior
Review Article: predictors of response to vedolizumab and ustekinumab in inflammatory bowel disease, by JF Colombel, MD, Ryan Ungaro, MD, et al, Alimentary Pharmacology & Therapeutics
Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America (Review), by Shirish Huprikar, MD et al, Transplantation
Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations, by Chitra Upadhyay, PhD, Roya Feyzezhad, Susan Zolla-Pazner, PhD, Caterina Hioe, PhD, et al, PLoS Pathogens
Bisphenol A Promotes Hyperuricemia via Activating Xanthine Oxidase, by John Cijiang He, MD, PhD, et al, The FASEB Journal
A Roadmap for Research on Resident Well-Being by Jonathan Ripp, MD, et al, American Journal of Medicine
Case Report: Induced Lactation in a Transgender Woman, Tamar Reisman, MD and Zil Goldstein, MSN, in Transgender Health
Tofacitinib in Patients with Ulcerative Colitis: Health-Related Quality of Life in Phase 3 Randomised Controlled Induction and Maintenance Studies Bruce E Sands, MD, and others in Journal of Crohn's and Colitis
The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease, Jean-Frederic Colombel, MD, Professor, Division of Gastroenterology, and others, in United European Gastroenterology Journal.
A Neoantigen Fitness Model Predicts Tumour Response To Checkpoint Blockade Immunotherapy Benjamin D. Greenbaum, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Pathology, Oncological Sciences, Icahn School of Medicine at Mount Sinai and Alexander Solovyov, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai in Nature
Genetics: Towards β-cell regeneration Andrew Stewart, MD, Director of the Diabetes, Obesity, and Metabolism Institute at the Icahn School of Medicine in Nature Reviews
Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis Paula Busse, MD, Associate Professor of Clinical Immunology at the Icahn School of Medicine at Mount Sinai, in New England Journal of Medicine.
Commensal bacteria make GPCR ligands that mimic human signalling molecules Louis Cohen, MD, Assistant Professor, Department of Medicine, Division of Gastroenterology in Nature
Identification of the Colicin V Bacteriocin Gene Cluster by Functional Screening of a Human Microbiome Metagenomic Library Louis Cohen, MD, Assistant Professor in ACS Infectious Diseases.
Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study Barbara Murphy, MD, in The Lancet.
Please take a look at some of the latest blogs from our DOM faculty members.
Popular diets: how to digest it all by gastroenterologist Dr. Joshua Novak for Our Town
Screening for colorectal cancer by gastroenterologist Dr. Pascale White for Our Town
Confronting flu season by infectious disease specialist Dr. Nicole Bouvier for Our Town
Syphilis in the City by infectious disease specialist Dr. Michelle Cespedes for Our Town
Take the Time to Check for Ticks by infectious disease specialist Dr. Christine Stavropoulos for Our Town
Sleep and the City by sleep medicine specialist Dr. Neomi Shah for Our Town
Spring and Allergy Season Have Sprung by immunologist Dr. Shradha Agarwal for Our Town
Is it a cold or do I have allergies in the winter? by immunologist Dr. Shradha Agarwal for Our Town
Thyroid Cancer: It’s Not Simply a Pain in the Neck by endocrinologist Dr. Deena Adimoolam for Our Town
Early Intervention May Prevent Irreversible Damage in Inflammatory Bowel Disease by gastroenterologist Dr. Ryan Ungaro for Inside Mount Sinai
Why the Benefits of Hepatitis C Drug Therapies Outweigh the Risks by liver specialist, Dr. Douglas Dieterich for Inside Mount Sinai
Researchers Identify Genes That Predict Damage in Donated Kidneys, Dr. Barbara Murphy for in Inside Mount Sinai
How Might Physical Exercise Stimulate Bone Synthesis? by endocrinologist Dr. Mone Zaidi for Inside Mount Sinai
Delay in Diagnosing Psoriatic Arthritis Can Have Dire Consequences by rheumatologist Dr. Yousaf Ali for Inside Mount Sinai
Remote Monitoring Improves Readmission Rates for Heart Failure Patients, cardiologist Dr. Sean Pinney for Inside Mount Sinai
A New Focus of Study for Liver Disease Specialists, liver specialist Dr. Scott Friedman for Inside Mount Sinai
Rare Tumor May Provide Road Map to Diabetes Therapies, endocrinologist Dr. Andrew Stewart for Inside Mount Sinai
Blocking a Hormone Builds Bone and Burns Fat At Menopause, a Promising Study Finds, endocrinologist Dr. Andrew Stewart for Inside Mount Sinai
Leader in Polycystic Ovary Syndrome Research is Chief of Endocrinology, Diabetes and Bone Disease, endocrinologist Dr. Andrea Dunaif for Inside Mount Sinai
Patient's Art Brightens Cancer Treatment Center, cancer specialist Dr. Sundar Jagannath for Inside Mount Sinai
Chief of Mount Sinai Heart Leads Panel on Global Health, cardiologist Dr. Valetin Fuster for Inside Mount Sinai