The Leon and Norma Hess Center for Science and Medicine

Departments and Institutes

The Leon and Norma Hess Center for Science and Medicine houses both clinical services and research facilities for some of the Mount Sinai Health System's most renowned Departments and Institutes. This spacious, state-of-the-art Center brings physicians, investigators, and specialists from a spectrum of disciplines together in the tireless pursuit of cutting-edge science and innovative medicine.

"The Leon and Norma Hess Center for Science and Medicine underscores the Mount Sinai Health System’s ongoing commitment to bringing critical therapies from bench to bedside." – Kenneth L. Davis, MD, President and CEO, the Mount Sinai Health System

Dedicated to eradicating the spread of cardiovascular disease, our Cardiovascular Research Institute is the living representation of our century-old commitment to excellence in patient care, education, and medical science. “Our research and clinical paradigms are laying the foundation for novel therapies based on basic science, and used to combat cardiovascular diseases," says Valentin Fuster, MD, PhD, Director of Mount Sinai Heart. The Institute's customized research space in the Center for Science and Medicine supports this paradigm, advancing the work of investigators striving to expand human knowledge of cardiovascular pathology. The rapid translation of innovative research concepts into prevention, diagnosis, and therapy means that patients of all ages struggling with cardiovascular diseases can look forward to multidisciplinary treatments of unprecedented quality.

Learn more about the Cardiovascular Research Center

Dedicated to improving the lives of infants, children, and adolescents, The Mindich Child Health and Development Institute fosters an intellectually rich and supportive environment for collaborative scientific investigation.

"Children have unique vulnerabilities with no counterpart in adult life, and their biology and vulnerability to illness evolve as they mature from infancy to adolescence," says Bruce D. Gelb, MD, Gogel Family Chair and Director. The Institute explores that unique biology by integrating the latest technologies with a modern research layout. We are developing innovative paradigms to better understand the effects of genetics and environment on child health, and to bring greater personalization to pediatric medicine. With the Mount Sinai Health System’s vast resources, our Institute is among the world's leading centers of children's health research.

Learn more about The Mindich Child Health and Development Institute

The Mount Sinai Health System has been recognized as a leader in brain and spinal cord research and treatment for over a century. That long-standing reputation continues with The Friedman Brain Institute, and its two floors of fully-equipped lab space in the Hess Center. "What we have built here is no less than the best neuroscience research institute in the world," says Eric J. Nestler, MD, PhD, Director of the Friedman Brain Institute and the Nash Family Professor of Neuroscience.

Designed to facilitate breakthrough research, the Hess Center space supports investigators pursuing their best and biggest ideas. Scientists from different disciplines have the resources they need to explore revolutionary advances, giving patients with nervous system disorders hope for a better life. "Soon—I have no doubt—we will develop tests that will allow us to distinguish between many diseases and their subtypes and to build on those discoveries with the development of new treatments," says Dr. Nestler. "That's when the era of truly personalized medicine will begin for neuroscience, and The Friedman Brain Institute is uniquely equipped to get us there."

Learn more about The Friedman Brain Institute

At the Icahn Institute for Data Science and Genomic Technology, we are working to make biomedical research and healthcare delivery a more data-driven field that is evidence-based and patient-focused. We use vast datasets to look at multifaceted diseases and cutting edge biotechnologies to analyze new uniquely-tailored treatments. Through this, we aim to make novel personalized treatments available to patients faster than in the past.

Learn more about the Icahn Institute for Data Science and Genomic Technology 

The Mount Sinai Health System continues to make critically important contributions to the understanding and treatment of cancers, as it has for over a century. "Serving as a bridge across the Mount Sinai Health System and its many departments, institutes, and our 8 hospitals, The Tisch Cancer Institute is able to monitor and treat patients early—before their cancers become more aggressive—when their chances for positive outcomes are greatest," says Ramon Parsons, MD, PhD, Director of the Tisch Cancer Institute and Ward-Coleman Chair in Cancer Research. We are planning new fellowship training programs and recruiting clinical scientists to conduct more patient-based research in oncology, pathology, surgery, radiation oncology and immunotherapy research. The Institute’s new discoveries and attention to personalized medicine also extend beyond Mount Sinai’s hospital campuses to community outreach programs that address health care disparities and continue to build upon the strength of our population health initiatives.

Learn more about the Tisch Cancer Institute

With its expansion to a state-of-the-art space in the Hess Center for Science and Medicine, the Institute is positioned to take visualization technology to new levels, inventing and applying methodologies that will enable breakthroughs across Mount Sinai's other disciplines. The Institute supports collaborative opportunities by providing researchers and clinicians from our various institutes greater and more comprehensive access to complex imaging expertise and equipment — including the integration of emerging artificial intelligence and deep learning techniques — dramatically increasing the potential for making major discoveries at Mount Sinai.”

Learn more about the Translational and Molecular Imaging Institute