Conditions and Treatments

The Mount Sinai Children’s Brain and Spinal Tumor Center has the capability to treat nearly any type of brain or spinal tumor found in children. Our highly skilled team uses sophisticated neuroimaging and molecular neuropathology diagnostic studies to accurately diagnose these tumors and then work together with the patient and their family to formulate a comprehensive treatment plan that incorporates advanced neurosurgical, radiation, chemotherapeutic, and/or molecularly-based therapeutic approaches to achieve the best outcomes.


  • DIPG / Diffuse Midline Glioma
  • Neuroembryonal Tumors
    • Medulloblastoma
    • Atypical Teratoid Rhabdoid Tumor (ATRT)
    • Supratentorial Primitive Neuroectodermal Tumors (PNET)
    • Pineoblastoma
  • GBM / Glioma / Astrocytoma
  • Ependymoma
  • Choroid Plexus Tumors
  • Craniopharyngioma
  • Germ Cell Tumors
  • Pituitary Tumors
  • Neuroglial tumors
    • Ganglioglioma / DNET
  • Pleomorphic Xanthoastrocytoma (PXA)
  • Subependymal Giant Cell Astrocytoma (SEGA)
  • Optic Pathway Glioma
  • Plexiform Neurofibroma


Brain and Spine Tumor Surgery

  • Open and minimally invasive resections
  • Endoscopic surgery for ventricular and skull base tumors (pituitary, craniopharyngioma, rare tumors)
  • Minimally invasive biopsy with surgical navigation, robotics and/or endoscopy
  • Advanced brain and spine monitoring and mapping for tumors in critical functional regions
  • 5-ALA fluorescence-guided tumor resection

Hydrocephalus Management

  • Endoscopic minimally invasive hydrocephalus treatment
  • Ventricular shunt placement

Radiation Therapy

  • Proton Beam Therapy with Pencil Beam Scanning Technique at New York Proton Center
    • Craniospinal irradiation
    • Whole ventricular radiation
    • Focal irradiation for primary brain or spinal tumors
    • Re-irradiation of brain/spine tumors
  • Photon-based radiation therapy at Mount Sinai Hospital
    • Palliative 3D conformal treatment of brain and spinal metastases
    • Cranial radiation therapy for high-risk leukemia patients
    • Whole brain radiation therapy for children with brain metastases
    • Stereotactic radiosurgery / stereotactic body radiation therapy (SRS/SBET) for brain and spine tumors


Targeted Molecular Therapies

Clinical Trials