The research advances produced by the Icahn Institute for Data Science and Genomic Technology and the Department of Genetics and Genomic Sciences are routinely featured in the news, research publications, and other media.
News
Our faculty members are frequently featured in the news and in other academic publications.
New York Times: New research including scientists from the Department of Genetics and Genomic Sciences, indicates that the coronavirus began to circulate in the New York area by mid-February, weeks before the first confirmed case, and that travelers brought in the virus mainly from Europe, not Asia. Full story.
The Washington Post: A genetic variant called TTR V122I could lead to a higher risk of hereditary transthryretin amyloid cardiomyopathy - a potentially fatal disease caused by a protein buildup in the heart. Researchers including Ron Do from Icahn School of Medicine at Mount Sinai collaborated with a research team from the University of Pennsylvania School of Medicine on the study published in the Journal of the American Medical Association. (12.11.19) Full story.
Genome Web: A new epigenomic study of Clostridioides difficile has identified a highly conserved methyltransferase that may enable sporulation and could be targeted to treat infections. Researchers including Icahn School of Medicine's Gang Fang honed in on a highly conserved methyltransferase within not only their sample set but within a global array of C. difficile isolates. (11.26.19) Full story.
Genetic Engineering and Biotechnology News: Genetic studies have advanced our understanding of the pathogenesis of the inherited form of Parkinson’s disease (PD). Scientists at the Icahn School of Medicine including Bin Zhang at Mount Sinai have uncovered new molecular drivers of PD using the statistical technique known as multiscale gene network analysis (MGNA). (11.20.19) Full story.
Beckers Hospital Review: Mount Sinai Health System has received an HHS grant to build a second "big omics data engine," named BODE 2, to advance translational bioinformatics research and data-enabled clinical care. (11.19.19) Full story.
Lifehacker: Jose Clemente was interviewed by The Upgrade podcast by Lifehacker to discuss anything and everything involving human gut health and the microbiome. (10.8.19) Full story
We publish our own press releases highlighting the work of our accomplished faculty and staff.
Noted Alzheimer’s researcher will assume new role on January 1, 2021
Mount Sinai Launches COVID-19 App to Track Spread of Virus Across New York City
A team of data scientists, physicians, and engineers across the Mount Sinai Health System has come together to launch STOP COVID NYC, a web-based app to capture the symptoms and spread of COVID-19 in New York City
Researchers Identify Opportunities to Advance Genomic Medicine
Researchers including Judy Cho and Eimear Kenny highlight genetic discoveries from over the past 25 years.
Researchers from the Department of Genetics and Genomic Sciences found Clonal evolution of a tumor ecosystem depends on different selection pressures that are principally immune and treatment mediated.
Researchers Show Different Mutations in a Single Gene Can Wreak Many Types of Havoc in Brain Cells
December 19, 2019 - NRXN1 undergoes extensive alternative splicing, and non-recurrent heterozygous deletions in NRXN1 are strongly associated with neuropsychiatric disorders. The study published in Nature Genetics reported links to patient-specific, heterozygous intragenic deletions in NRXN1 to isoform dysregulation and impaired neuronal maturation and activity in a human and disease-relevant context.
December 12, 2019 - Researchers at the Icahn School of Medicine at Mount Sinai have identified novel genes associated with the severity of peanut allergy, as well as ways in which these genes interact with other genes during allergic reactions. The findings, published in the Journal of Allergy and Clinical Immunology, could lead to better treatments for peanut allergy.
Genetic Breakthrough Identifies Heart Failure Risk in African and Latino Americans
December 10, 2019 - A genetic variation believed to increase risk for heart failure in people of African or Latino ancestry has been identified in a new study by researchers from the Icahn School of Medicine at Mount Sinai and Perelman School of Medicine at the University of Pennsylvania. The study found that the transthyretin or TTR V122I genetic variant was significantly associated with heart failure and that heredity transthyretin amyloid cardiomyopathy (hATTR-CM) caused by this variant was confirmed at appreciable frequency in individuals of African or Latino ancestry. The results were published in JAMA.
New Discovery in C. difficile Biology Could Lead to Treatments for Dangerous Bacterial Infections
November 25, 2019 - A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that affect gene expression beyond the DNA genetic code, researchers at the Icahn School of Medicine at Mount Sinai report. This is the first discovery that epigenetics regulate sporulation in any bacteria. Their research, published November 25th in Nature Microbiology, opens a new window to developing treatments for this devestating infection.
Mount Sinai Researchers Uncover New Molecular Drivers of Parkinson’s Disease
November 20, 2019 - Scientists at the Icahn School of Medicine at Mount Sinai have uncovered new molecular drivers of Parkinson’s disease using a sophisticated statistical technique called multiscale gene network analysis (MGNA). The team was also able to determine how these molecular drivers impact the functions of genes involved in the disease. The results were published in Nature Communications.
Our latest videos featuring faculty in educational and news-based videos can be found on our YouTube page.