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Guidance on recombinant DNA molecules that are exempt from National Institutes of Health Guidelines and registration with the Institutional Biosafety Committee can be found here.
Guidance on definitions used in OSHA’S Health and Safety Regulations that require prior approvals for toxic compounds and carcinogens can be found here.
Guidance on experiments that require ISMMS’ Institutional Biosafety Committee approval before initiation as directed by the National Institutes of Health can be found here.
- Experiments Covered by the NIH Guidelines Specific guidance on which experiments have to be reported to the NIH Office of Biotechnology Activity, the MSSM Institutional Biosafety Committee in accordance with NIH requirements.
- Exemptions and Host-Vector Systems Guide Certain specified recombinant DNA molecules that consist entirely of DNA segments from different species that exchange DNA by known physiological processes, though one or more of the segments may be a synthetic equivalent, are exempt from the NIH Guidelines.
- Exempt Experiments – Definitions Certain recombinant DNA molecules are exempt from the NIH Guidelines, and registration with the Institutional Biosafety Committee is not required by the NIH.
- Rules for Filing Recombinant DNA Activities
Entrez Gene is NCBI's database for gene-specific information. It does not include all known or predicted genes; instead Entrez Gene focuses on the genomes that have been completely sequenced, that have an active research community to contribute gene-specific information, or that are scheduled for intense sequence analysis. The content of Entrez Gene represents the result of curation and automated integration of data from NCBI's Reference Sequence project (RefSeq), from collaborating model organism databases, and from many other databases available from NCBI. Records are assigned unique, stable and tracked integers as identifiers. The content (nomenclature, map location, gene products and their attributes, markers, phenotypes, and links to citations, sequences, variation details, maps, expression, homologs, protein domains, and external databases) is updated as new information becomes available. Entrez Gene is a step forward from NCBI's LocusLink, with both a major increase in taxonomic scope and improved access through the many tools associated with NCBI Entrez.
GeMCRIS is a comprehensive information resource and analytical tool for scientists, research participants, institutional oversight committees, sponsors, federal officials, and others with an interest in human gene transfer research. GeMCRIS allows users to access an array of information about human gene transfer trials registered with the NIH, including medical conditions under study, institutions where trials are being conducted, investigators carrying out these trials, gene products being used, route of gene product delivery, and summaries of study protocols.