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Improving CAR-T Cell Therapy with Tumor Macrophage Strategy

New approach starts immune response against cancer cells
immunology

Department of Immunology and Immunotherapy

DEPARTMENTS AND OFFICES

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Established in June 2023, the Department of Immunology and Immunotherapy builds on the Icahn School of Medicine at Mount Sinai’s long history of immunobiological research. The Department believes we need a sustained focus on the basic scientific concepts governing the immune system in order to drive innovation. Understanding the central pathways and processes that control immune cell development and differentiation, and how their molecular states and functional activities are shaped by their specific tissue environment, is critical to appreciating how they influence all aspects of human health and disease.

The Department collaborates extensively with the Icahn Institute of Genomics to develop advanced gene and cell engineering technologies that will enable researchers to study the immune system. In this way, the Department plays a key role in elevating fundamental immunology research efforts at Mount Sinai. These efforts feed into more multidisciplinary and translational immunology research programs, including those at the Marc and Jennifer Lipschultz Precision Immunology Institute.

This research field requires a highly skilled work force of biomedical researchers and physician scientists who have strong foundations in immunology. To address this need, our Department serves as the central administrative hub to support training graduate and postdoctoral immunologists across the medical school. Our commitment to training is exemplified by our diverse National Institutes of Health-funded training programs that focus on immunology. These programs include the Translational Immunology Training Program, the Systems Skin Biology Training Program, and the Postdoctoral Gastro-Intestinal and Liver Diseases Fellowship Program.

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Message From the Chairs

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Miriam Merad, MD, PhD

Chair of the Department of Immunology and Immunotherapy

Miriam Merad, MD, PhD, is the Chair of the Department of Immunology and Immunotherapy, the Director of the Marc and Jennifer Lipschultz...

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Brian D Brown, PhD

Vice-Chair of the Department of Immunology and Immunotherapy

Dr. Brian Brown is an immunologist and molecular biologist whose research has a strong focus on biotechnology and therapeutics. His training...

Promoting Research and Education

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Dusan Bogunovic, PhD Awarded the 2023 ICIS-Luminex John R. Kettman Award for Excellence in Cytokine & Interferon Research

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Dusan Bogunovic, PhD Awarded the 2023 ICIS-Luminex John R. Kettman Award for Excellence in Cytokine & Interferon Research

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Mount Sinai Medical Science Training Program Student Recognized for Combating Anti-Asian Racism and Hate Crimes

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Image of TREM2+ Tumor Macrophages Chosen as Biomedical Picture of the Day by the MRC London Institute of Medical Sciences

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Featured Immunology and Immunotherapy Achievements

Miriam Merad, PhD receives the 2020 Jacobi Medallion
View What Our PhD in Biomedical Sciences Immunology Training Program Offers
Negative Regulation of Type I Interferon Disrupts Viral Control in Individuals With Down Syndrome
Brian Brown, PhD: The Quest for Breakthrough Therapies
Cancer Precision Medicine Retreat -- Session 4: Jeremiah Faith, PhD

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immunology
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