Seminar Series

The Department of Pharmacological Sciences hosts a biweekly research seminar series by invited speakers on the topics of drug design and discovery, and molecular and systems pharmacology, held on Thursdays at 11 am in the Hess Center for Science and Medicine building. If you’re interested in joining the mailing list for this Seminar Series in the future, please contact DPS@mssm.edu.

Date

Details

November 11

TBA
Klarissa Dawaniette Jackson, Ph.D.
UNC
Diversity Lecture
Hosted by Lakshmi Devi, Ph.D.

October 28

TBA
Andrew Kruse, Ph.D.
Harvard Medical School
Hosted by Daniel Wacker, Ph.D.

September 16

TBA
Alfonso Mondragon, Ph.D.
Northwestern University
Hosted by Aneel Aggarwal, Ph.D.

September 2

TBA
Nurulain T. Zaveri, Ph.D.
Astraea Therapeutics
Hosted by Lakshmi Devi, Ph.D.

August 5

TBA
Catherine Cahill, Ph.D.
University of California at Los Angeles
Hosted byLakshmi Devi, Ph.D.

June 24

TBA
Tom Walz, Ph.D.
The Rockefeller University
Hosted by Marta Filizila, Ph.D.

June 10

TBA
Susan Steinberg, M.D.
Columbia University
Hosted by Lakshmi Devi, Ph.D.

May 27

TBA
Hiro Furukawa, Ph.D.
Cold Spring Harbor
Hosted by Marta Filizila, Ph.D.

May 13

TBA
Jana Shen, Ph.D.
University of Maryland
Hosted by Avner Schlessinger, Ph.D.

April 29

“Insights into GPX4 and ferroptosis through analysis of a patient variant”
Brent Stockwell, Ph.D.
Columbia University
Hosted by Robert DeVita, Ph.D.

April 15

“BRD4 in Transcription Programming and Cancer Therapy”
Cheng-Ming Chiang, Ph.D.
UT Southwestern
Hosted by Ming-Ming Zhou, Ph.D.

April 8

“Engineering the Premetastatic Niche”
Luis Solorio, Ph.D.
Purdue University
Hosted by Maria Soledad Sosa, Ph.D.

March 4

“Structural Mechanisms of AMPA Receptor Regulation and Gating’
Alexander Sobolevsky, Ph.D.
Columbia University
Hosted by Marta Filizola, Ph.D.

February 11

"Mechanics of an Nramp Family Transition Metal Transporter”
Rachelle Gaudet, Ph.D.
Harvard University
Hosted by DPS Student and Postdoc Association

January 14

"Designing Bitopic or Bivalent Molecules for the Treatment of Substance Use Disorders"
Amy Newman, Ph.D.
NIH/NIDA/IRB
Hosted by Lakshmi Devi, Ph.D.

Date

Details

December 17

“Circuit and Synaptic Mechanisms Underlying Vulnerability for Drug Abuse”
Veronica Alvarez, Ph.D.
National Institutes of Health 
Hosted by Ming-Hu Han, Ph.D.

October 29

"Neurobiological pathways lead the development of novel treatments for opioid addiction"
Yasmin Hurd, Ph.D.
Icahn School of Medicine 
Diversity Lecture
Hosted by DPS Student and Postdoc Association

October 1

“Selective inhibition and degradation of oncogenic RAS mutants, with a touch of COVID"
Shohei Koide, Ph.D.
NYU Langone 
Hosted by Ming-Ming Zhou, Ph.D.

September 17

Early life stress and susceptibility to schizophrenia and depression
Anthony Grace, Ph.D.
University of Pittsburgh 
Hosted by Ming-Hu Han, Ph.D.

February 6

Integrating 3D structure into Systems Biology
Barry Honig, Ph.D.
Columbia University 
Hosted by Avner Schlessinger, Ph.D.

January 23

Synthetic Targeting of Protein-Protein Interactions in Cancer
Bobby Arora, Ph.D.
New York University 
Hosted by Robert DeVita

Date

Details

December 5

"Complex Dynamics of Glutamate Transporters"
Olga Boudker, Ph.D.
Weill Cornell Medicine
Hosted by DPS Student and Postdoc Association

November 7

"The Sodium/Iodide Symporter (NIS): From Patient to Molecule and Back"
Nancy Carrasco, M.D.
Yale University
Hosted by Lakshmi Devi, Ph.D.

October 17

"RNA Methylation in Gene Regulation and Cancer"
Richard Gregory, Ph.D.
Harvard University
Hosted by Martin Walsh, Ph.D.

October 3

"Arginine Methylation -Substrates, Effectors & Crosstalk"
Mark T. Bedford, MD, Ph.D.
Anderson Cancer Center,
University of Texas 
Hosted by Jian Jin, Ph.D.

September 19

"Designing the Next Generation of Computational Microscopes with Statistical Mechanics and Artificial Intelligence"
Pratyush Tiwary, Ph.D.
University of Maryland 
Hosted by Marta Filizola, Ph.D.

June 20

“Redox-inactivation of Cardiomyocyte Beta1-adrenergic receptors: Carvedilol to the Rescue"
Susan F. Steinberg, M.D.
Columbia University 
Hosted by Lakshmi Devi, Ph.D.

June 6

"Biological Photocontrol: From Optogenetic Engineering to Phototherapeutics"
David S. Lawrence, Ph.D.
University of North Carolina
Hosted by Jian Jin, Ph.D.

May 16

“Acetylcholine Signaling and Stress-Induced Behaviors”
Marina Picciotto, Ph.D.
Yale University 
Hosted by Lakshmi Devi, Ph.D.

May 2

"Cryo-EM and Integrative Structural Biology"
Sriram Subramaniam, Ph.D.
NIH, Center for Cancer Research
Hosted by Robert DeVita, Ph.D.

April 18

“Exploring novel roles of Disheveled in cancer biology and transcription regulation” 
Kevin Pruitt, Ph.D.
Texas Tech University 
Hosted by Martin Walsh, Ph.D.

April 4

“Molecular Mechanisms of TRPV Channels Gating by Endogenous and Exogenous Modulators”​
Vera Moiseenkova-Bell, Ph.D.
University of Pennsylvania
Hosted by Marta Filizola, Ph.D.

March 19

“Network analysis and visualization with STRING and Cytoscape”​
Lars Juhl Jensen, Ph.D.
Copenhagen University 
Hosted by Avi Ma’ayan, Ph.D.

March 7

“Endosomal pH as a Therapeutic Target in Neurodegenerative Disease”
Rajini Rao, Ph.D.
The John’s Hopkins University 
Hosted by Avner Schlessinger, Ph.D.

February 21

“GPCR Signaling in Osteoblasts by Parathyroid Hormone and its Analogs”
Nicola C. Partridge, Ph.D.
New York University 
Hosted by Lakshmi Devi, Ph.D.

February 7

“Regulation of Notch Signaling by O-Glycans”
Pamela Stanley, Ph.D.
Albert Einstein College of Medicine 
Hosted by Lakshmi Devi, Ph.D.

January 17

”Dendritic Integration and Fragile X Syndrome”
Daniel Johnston, Ph.D.
University of Texas, Austin 
Hosted by Ming-Hu Han, Ph.D.

Date

Details

December 13

“A Weird Ion Channel for a Weird Ion”
Christopher Miller, Ph.D.
Brandeis University
Hosted by Manisha Vaish, Ph.D.

November 29

“Epigenetic Regulation of Adipose Tissue Distribution"
Steven R. Smith, Ph.D.
Florida Hospital Research
Hosted by Martin Walsh, Ph.D.

October 4

“To be or not to be, a dilemma of cellular metabolism”
Xuejun Jiang, Ph.D.
Memorial Sloan Kettering Cancer Center
Hosted by Michael Lazarus, Ph.D.

September 20

“Integrated Connectivity Map”
Aravind Subramanian, Ph.D.
The Broad Institute
Hosted by Avi Ma’ayan, Ph.D.

June 28

Structure, Function, and Modulation of Serotonin (3A) Receptors”​
Sudha Chakrapani, Ph.D.
Case Western Reserve University
Hosted by Marta Filizola, Ph.D.

June 25

Harnessing the Potential of Cryo-EM Through Protein Design” 
Shane Gonen, Ph.D.
University of California
Hosted by Ming-Ming Zhou, Ph.D.

June 14

From Explorations in Discovery Biology to a Targeted Approach for Colon Cancer”​
Jef K. De Brabander, Ph.D.
University of Texas
Hosted by Robert DeVita, Ph.D.

June 7

GPCR Signaling Platforms for Pain and Analgesia
Meritxell Canals, Ph.D.
Monash University
Hosted by Lakshmi Devi, Ph.D.

May 31

Identification of a Novel Therapeutic Agent for Autism-like Social Deficits”​
Zhen Yan, Ph.D.
University of New York at Buffalo
Hosted by Ming-Hu Han, Ph.D.

May 10

Bisubstrate Analogues as N-Methyltransferase Inhibitors and Tools for Structural Studies”​
Nathaniel Martin, Ph.D.
Utrecht University
Hosted by Jian Jin, Ph.D.

May 7

A Novel Form of Endocannabinoid-Dependent LTP is Critical for Encoding Elements of Episodic Memory
Christine Gall, Ph.D.
University of California
Hosted by Ming-Hu Han, Ph.D.

May 3

"MicroED Opens a New Era for Biological Structure Determination"
Tamir Gonen, Ph.D.
University of California at Los Angeles
Hosted by Michael Lazarus, Ph.D.

April 19

"Inhibitor Control of the Gut Microbiota”
Matthew Redinbo, Ph.D.
University of North Carolina at Chapel Hill
Hosted by Jian Jin, Ph.D.

April 5

"Drug Design Targeting PRMT5"
Chenglong Li, Ph.D.
University of Florida
Hosted by Jian Jin, Ph.D.

March 22

"Atomic Resolution Cryo-EM"
Sriram Subramaniam, Ph.D.
NCI/NIH
Hosted by Robert DeVita, Ph.D.

March 1

"Integrating Metabolism and Chromatin Biology in the Regulation of Stem Cell Identity"
Bryce Carey, Ph.D.
The Rockefeller University
Hosted by Ming-Ming Zhou, Ph.D.

February 22

"Endosomal Platforms for the Signaling Train to Pain"
Nigel Bunnett, Ph.D.
Columbia University
Hosted by Ming-Hu Han, Ph.D.

February 12

"Investigation of regulatory mechanisms for chromatin modifications and compaction using mass spectrometry"
Simone Sidoli, Ph.D.
University of Pennsylvania
Hosted by Ming-Ming Zhou, Ph.D.

February 8

"The Structure and Function of the CB1 Cannabinoid Receptor"
Alexandros Makriyannis, Ph.D.
Northeastern University
Hosted by Lakshmi Devi, Ph.D.

January 25

"Expanding the Druggable Proteome through Cereblon-Mediated Protein Degradation"
Lawrence G. Hamann, Ph.D.
Celgene Corporation
Hosted by Jian Jin, Ph.D.

January 11

"Molecular Mechanisms of Active Transport: An Energy-landscape Perspective"
Seth H. Weinberg, Ph.D.
Virginia Commonwealth University
Hosted by Eric Sobie, Ph.D.

Date

Details

December 14

"Translational Drug Interaction Research"
Lang Li, Ph.D.
The Ohio State University
Hosted by Avi Ma’ayan, Ph.D.

November 16

"Genome, Epigenome, and Metagenome Diagnostics on Earth and in Space"
Christopher E. Mason, Ph.D
Weill Cornell Medicine
Hosted by Avi Ma’ayan, Ph.D.

November 30

"Ketamine Metabolism to Hydroxynorketamines: Pharmacology Underlying Fast Antidepressant Action"
Todd D. Gould, M.D.
University of Maryland
Hosted by Ming-Hu Han, Ph.D.

October 26

"Chemical Genetic Discovery of Novel Kinase Inhibitors"
Arvin Dar, Ph.D.
Icahn School of Medicine at Mount Sinai
Hosted by Jian Jin, Ph.D.

October 5

"Chemical Biology and Differential HDX to
Probe Ligand Mediated Receptor Signaling"
Patrick R. Griffin, Ph.D.
The Scripps Research Institute
Hosted by Jian Jin, Ph.D.

September 28

"Therapy Acceleration via Precision Medicine"
Sharad Verma, Ph.D.
The John’s Hopkins University
Hosted by Jian Jin, Ph.D.

September 19

"WD-40 Repeat Proteins: A Novel Target Class?"
Matthieu Schapira, Ph.D.
University of Toronto
Hosted by Jian Jin, Ph.D.

June 26

"Chromatin Modification, Gene Regulation and Cancer"
G. Greg Wang, Ph.D.
University of North Carolina at Chapel Hill
Hosted by Jian Jin, Ph.D. & Martin Walsh, Ph.D.

May 25

"Structural and Molecular Basis of Psychoactive Drug Action at GPCRs”
Daniel Wacker, Ph.D.
University of North Carolina at Chapel Hill
Hosted by Ming-Ming Zhou, Ph.D.

May 18

"Decode the Noncoding: Understand the Majority for Precision Medicine"
Housheng Hansen He, Ph.D.
University of Toronto
Hosted by Martin Walsh, Ph.D.

May 17

"Intestinal Stem Cell Self-Renewal: Insights from Ligand-Level Perturbation of WNT Signaling"
Kelley Yan, M.D., Ph.D.
Columbia University
Hosted by Ming – Ming Zhou, Ph.D.

May 4

"Novel Approaches to Drug Discovery for Central Nervous System Disorders"
Irene Morganstern, Ph.D.
Psychogenics Inc.
Hosted by Avi Ma’ayan, Ph.D.

April 13

"Identifying and Manipulating Epigenetic Cell Fate Barriers"
Andres Blanco, Ph.D.
Harvard Medical School
Hosted by Ming-Ming Zhou, Ph.D.

April 6

"Transcriptional Repression by MAF1: Implications for Cancer and Obesity”
Ian Willis, Ph.D.
Albert Einstein College
Hosted by Lakshmi Devi, Ph.D.

March 30

"Cardiac Systems Pharmacology to Predict Drug Effects, Understand Mechanisms, and Personalize Therapies"
Eric A Sobie, Ph.D.
Icahn School of Medicine at Mount Sinai
Hosted by Aneel Aggarwal, Ph.D.

March 23

"Targeting Aberrant Signaling Pathways in Primary Brain Tumors"
Ingo Mellinghoff, M.D.
Memorial Sloan Kettering Cancer Center
Hosted by Martin Walsh, Ph.D.

March 16

"Using Proteomics to Uncover Lysine Methylation as a Global Actor in Biology and Disease"
Scott Carlson, Ph.D.
Stanford University
Hosted by Ming-Ming Zhou, Ph.D.

March 9

"Calcium Signaling and the Plasticity of Glutamatergic Synapses"
Edward B. Ziff, Ph.D.
New York University
Hosted by Ming-Hu Han, Ph.D.

February 22

"RNA-binding proteins as regulators of cell fate in development and disease"
Jernej Murn, Ph.D.
Harvard Medical School
Hosted by Martin Walsh, Ph.D.

January 26

"Molecular Mechanisms of Active Transport: An Energy-landscape Perspective"
José D. Faraldo-Gómez, Ph.D.
National Institutes of Health
Hosted by Avner Schlessinger, Ph.D.