Seminar Series

The Department of Pharmacological Sciences hosts a biweekly research Seminar Series by invited speakers on the topics of drug design and discovery, and molecular and systems pharmacology, held on Thursdays at 11 am in the Hess Center for Science and Medicine building. If you’re interested in joining the mailing list for this Seminar Series in the future, please contact DPS@mssm.edu.

2023

Date

Details

December 8

“Learning about Prostate Cancer by Studying Mouse Models”

Cory Abate-Shen, Ph.D.
Columbia university
Hosted by Janice Yang

October 19

“Cancer Drug Discovery using Fragment-Based Methods”

Stephen Fesik, Ph.D.
Vanderbilt University
Hosted by Ming-Ming Zhou, Ph.D.

October 12

“DNA-Encoded Library Technology: A Valuable Tool for Drug Discovery and Biomedical Research”

Matthew A. Clark, Ph.D.
X-Chem, Inc.
Hosted by Robert DeVita, Ph.D.

June 22

“Intrinsically Disordered Domains in the Phosphoregulation of Transporter Activity”

Thomas Tomasiak, Ph.D.
University of Arizona
Hosted by Avner Schlessinger, Ph.D.

June 8

“Towards Translational Clinical Proteomics”

Jun Qin, Ph.D
National Center of Protein Sciences (Beijing)
Hosted by Yi Shi, Ph.D.

May 11

“The Role of Innate-like T Cells in Protecting Meningeal Integrity and Cognitive Function”

Qi Yang, M.D.

Rutgers University
Hosted by William Cheung, Ph.D.

April 27

“Identifying Inhibitors of Antibiotic Resistance Enzymes Using DNA-encoded Chemical Libraries”

Tim Pazkill, Ph.D.
Baylor College of Medicine
Hosted by Yi Shi, Ph.D.

April 13

“Mechanisms and Roles of Fast Dopamine Signaling”

Pascal Kaeser, M.D.
Harvard University

Hosted by Jinye Dai, Ph.D.

March 30

“Transforming Academic Drug Discovery: From Concept to an On Demand, Non-hormonal Male Contraceptive”

Peter T. Meinke, Ph.D.
Tri-Institutional Therapeutics Discovery Institute
Hosted by Robert DeVita, Ph.D.

March 16

“Epigenetic Control of Regulatory T Cell Suppressive Capacity”
Yongqiang Feng, Ph.D.
St. Jude Children's Research Hospital
Hosted by William Cheung, Ph.D.

January 19

“Architecture of Erythrocyte Ankyrin-1 Complexes”
Oliver Clarke, Ph.D.
Columbia University
Hosted by Daniel Wacker, Ph.D.

January 12

" Regulation of GPCR Signaling by Ubiquitination"

Sudha Shenoy, Ph.D.
Duke University Medical Center
Hosted by Lakshmi Devi, Ph.D.

Date

Details

November 3

“Targeting Dysfunctions in Protein-Protein Interaction Networks"
Gabriela Chiosis, Ph.D.
Sloan Kettering Institute
Hosted by Lakshmi Devi, Ph.D.

October 20

“Targeting New Signal Pathways for Prevention and Treatment of Cancer and Diabetes”
Lorraine Gudas, Ph.D.
Weill Cornell Medicine
Hosted by Lakshmi Devi, Ph.D.

September 22

“Exploiting a Unique Post-Translational Modification to Enhance
Subunit Selection and Activity of a Tumor Suppressor Complex”
Derek Taylor, Ph.D.
Case Western University
Hosted by Yi Shi, Ph.D.

June 17

“A Unifying Mechanism for Drug-Induced Formation of New Oligodendrocytes”
Drew Adams, Ph.D.
Case Western Reserve University
Hosted by Aneel Aggarwal, Ph.D.

June 8

“Targeting Ion Channels for Drug Discovery - Cardiac Arrhythmia & COVID-19”
Masayuki Yazawa, Ph.D.
Columbia University Irving Medical Center
Hosted by Aneel Aggarwal, Ph.D.

May 11

“Mechanisms of Enhancer Assembly: What can we Learn to Develop Pharmacological Interventions for Cancers”
Zhijie Liu, Ph.D.
University of Texas Health Science Center at San Antonio
Hosted by Aneel Aggarwal, Ph.D.

May 5

“Mechanism of Pathogenic Endothelial and Podocyte Cross-Talk”
Ilse S. Daehn, Ph.D.
Icahn School of Medicine at Mount Sinai
Hosted by Maria Sosa, Ph.D.

April 21

“Molecular Simulations in the Times of COVID-19 and the Opioid Crisis”
Jana Shen, Ph.D.
University of Maryland
Hosted by Avner Schlessinger, Ph.D.

April 7

“Molecular Mechanisms of Epigenetic Regulation”
Tatiana Kutateladze, Ph.D.
University of Colorado School of Medicine
Hosted by Ming-Ming Zhou, Ph.D.

February 24

“Translational Pharmacogenomics Advances in the Mount Sinai Health System”
Aniwaa Owusu-Obeng, Pharm.D.
Icahn School of Medicine at Mount Sinai
Hosted by Maria Sosa, Ph.D.

February 10

“Antibodies Against Emerging Infectious Disease”
Erica Ollmann Saphire, Ph.D.
La Jolla Institute for Immunology
Hosted by DPS Student and Postdoc Association

January 13

"Computational Microscopy of SARS-CoV-2"
Rommie Amaro, Ph.D.
The University of California San Diego
Hosted by Marta Filizola, Ph.D.

Date

Details

November 11

"Interindividual Variability in Drug Metabolism and Bioactivation: Implications for Ethnically Diverse Populations"
Klarissa Dawaniette Jackson, Ph.D.
UNC
Diversity Lecture
Hosted by Lakshmi Devi, Ph.D.

October 28

"Nanobodies as Tools to Interrogate Transmembrane Receptor Signaling"
Andrew Kruse, Ph.D.
Harvard Medical School
Hosted by Daniel Wacker, Ph.D.

September 16

"Topoisomerase V: The Forgotten Topoisomerase and Other Stories"
Alfonso Mondragon, Ph.D.
Northwestern University
Hosted by Aneel Aggarwal, Ph.D.

September 2

"Multidisciplinary Journey Integrating Basic Sciences and Translational Drug Discovery to validate a First-in-class Target and Pharmacotherapy for Addictive Disorders"
Nurulain T. Zaveri, Ph.D.
Astraea Therapeutics
Hosted by Lakshmi Devi, Ph.D.

August 5

“Impact of Chronic Pain on Mesolimbic Reward Circuitry”
Catherine Cahill, Ph.D.
University of California at Los Angeles
Hosted by Lakshmi Devi, Ph.D.

June 10

“N-tertaining a New Signaling Paradigm for Protease Regulated Cardiomyocyte beta1-Adrenergic Receptors”
Susan Steinberg, M.D.
Columbia University
Hosted by Lakshmi Devi, Ph.D.

May 27

“Dissecting Molecular Machinery for Neurotransmission and Neuromodulation”
Hiro Furukawa, Ph.D.
Cold Spring Harbor
Hosted by Marta Filizila, Ph.D.

April 29

“Insights into GPX4 and ferroptosis through analysis of a patient variant”
Brent Stockwell, Ph.D.
Columbia University
Hosted by Robert DeVita, Ph.D.

April 15

“BRD4 in Transcription Programming and Cancer Therapy”
Cheng-Ming Chiang, Ph.D.
UT Southwestern
Hosted by Ming-Ming Zhou, Ph.D.

April 8

“Engineering the Premetastatic Niche”
Luis Solorio, Ph.D.
Purdue University
Hosted by Maria Soledad Sosa, Ph.D.

March 4

“Structural Mechanisms of AMPA Receptor Regulation and Gating’
Alexander Sobolevsky, Ph.D.
Columbia University
Hosted by Marta Filizola, Ph.D.

February 11

"Mechanics of an Nramp Family Transition Metal Transporter”
Rachelle Gaudet, Ph.D.
Harvard University
Hosted by DPS Student and Postdoc Association

January 14

"Designing Bitopic or Bivalent Molecules for the Treatment of Substance Use Disorders"
Amy Newman, Ph.D.
NIH/NIDA/IRB
Hosted by Lakshmi Devi, Ph.D.

Date

Details

December 17

“Circuit and Synaptic Mechanisms Underlying Vulnerability for Drug Abuse”
Veronica Alvarez, Ph.D.
National Institutes of Health 
Hosted by Ming-Hu Han, Ph.D.

October 29

"Neurobiological pathways lead the development of novel treatments for opioid addiction"
Yasmin Hurd, Ph.D.
Icahn School of Medicine 
Diversity Lecture
Hosted by DPS Student and Postdoc Association

October 1

“Selective inhibition and degradation of oncogenic RAS mutants, with a touch of COVID"
Shohei Koide, Ph.D.
NYU Langone 
Hosted by Ming-Ming Zhou, Ph.D.

September 17

Early life stress and susceptibility to schizophrenia and depression
Anthony Grace, Ph.D.
University of Pittsburgh 
Hosted by Ming-Hu Han, Ph.D.

February 6

Integrating 3D structure into Systems Biology
Barry Honig, Ph.D.
Columbia University 
Hosted by Avner Schlessinger, Ph.D.

January 23

Synthetic Targeting of Protein-Protein Interactions in Cancer
Bobby Arora, Ph.D.
New York University 
Hosted by Robert DeVita

Date

Details

December 5

"Complex Dynamics of Glutamate Transporters"
Olga Boudker, Ph.D.
Weill Cornell Medicine
Hosted by DPS Student and Postdoc Association

November 7

"The Sodium/Iodide Symporter (NIS): From Patient to Molecule and Back"
Nancy Carrasco, M.D.
Yale University
Hosted by Lakshmi Devi, Ph.D.

October 17

"RNA Methylation in Gene Regulation and Cancer"
Richard Gregory, Ph.D.
Harvard University
Hosted by Martin Walsh, Ph.D.

October 3

"Arginine Methylation -Substrates, Effectors & Crosstalk"
Mark T. Bedford, MD, Ph.D.
Anderson Cancer Center,
University of Texas 
Hosted by Jian Jin, Ph.D.

September 19

"Designing the Next Generation of Computational Microscopes with Statistical Mechanics and Artificial Intelligence"
Pratyush Tiwary, Ph.D.
University of Maryland 
Hosted by Marta Filizola, Ph.D.

June 20

“Redox-inactivation of Cardiomyocyte Beta1-adrenergic receptors: Carvedilol to the Rescue"
Susan F. Steinberg, M.D.
Columbia University 
Hosted by Lakshmi Devi, Ph.D.

June 6

"Biological Photocontrol: From Optogenetic Engineering to Phototherapeutics"
David S. Lawrence, Ph.D.
University of North Carolina
Hosted by Jian Jin, Ph.D.

May 16

“Acetylcholine Signaling and Stress-Induced Behaviors”
Marina Picciotto, Ph.D.
Yale University 
Hosted by Lakshmi Devi, Ph.D.

May 2

"Cryo-EM and Integrative Structural Biology"
Sriram Subramaniam, Ph.D.
NIH, Center for Cancer Research
Hosted by Robert DeVita, Ph.D.

April 18

“Exploring novel roles of Disheveled in cancer biology and transcription regulation” 
Kevin Pruitt, Ph.D.
Texas Tech University 
Hosted by Martin Walsh, Ph.D.

April 4

“Molecular Mechanisms of TRPV Channels Gating by Endogenous and Exogenous Modulators”​
Vera Moiseenkova-Bell, Ph.D.
University of Pennsylvania
Hosted by Marta Filizola, Ph.D.

March 19

“Network analysis and visualization with STRING and Cytoscape”​
Lars Juhl Jensen, Ph.D.
Copenhagen University 
Hosted by Avi Ma’ayan, Ph.D.

March 7

“Endosomal pH as a Therapeutic Target in Neurodegenerative Disease”
Rajini Rao, Ph.D.
The John’s Hopkins University 
Hosted by Avner Schlessinger, Ph.D.

February 21

“GPCR Signaling in Osteoblasts by Parathyroid Hormone and its Analogs”
Nicola C. Partridge, Ph.D.
New York University 
Hosted by Lakshmi Devi, Ph.D.

February 7

“Regulation of Notch Signaling by O-Glycans”
Pamela Stanley, Ph.D.
Albert Einstein College of Medicine 
Hosted by Lakshmi Devi, Ph.D.

January 17

”Dendritic Integration and Fragile X Syndrome”
Daniel Johnston, Ph.D.
University of Texas, Austin 
Hosted by Ming-Hu Han, Ph.D.