Here is a list of the research laboratories of primary faculty members in the Department of Pharmacological Sciences.
Protein-nucleic acid interactions in DNA and RNA metabolism
Exploring post-transcriptional regulation of bacterial gene expression
Investigating genetic and environmental factors in neuropsychiatric disease etiology and corresponding synaptopathies.
Focusing on neuropeptides, opiate receptor signal transduction and narcotic addiction
Small molecule drug discovery, chemical biology, and target validation
Computer-aided structural biology and drug discovery
Mechanism of epigenetic alterations in cardiopulmonary vascular disease, calcium handling proteins, and small molecules inhibitors and target gene therapies.
Neurophysiological mechanisms of depression and alcohol addiction in rodent models
Systems biology and systems pharmacology, cell signaling networks with emphasis on GPCR pathways
Medicinal chemistry and drug discovery: creating selective inhibitors of histone methyltransferases, biased ligands of GPCRs, and novel degraders targeting oncogenic proteins
Cellular mechanisms of nutrient signaling in intracellular glycosyation and authophagy with chemistry, crystallography and mass spectrometry methods
Computational systems biology, bioinformatics, data mining, data science, data integration, and software development for biomedical and biological research
Focusing on connective tissue pathophysiology and genetic control of morphogenesis
The role of cell cycle and apoptotic genes in cancer progression and as target for the development of novel anticancer drugs
Structural bioinformatics and structure-based drug design membrane transporters
Mass spectrometry-based proteomics, protein design, antibody therapeutics and translational sciences
Mathematical modeling and quantitative investigation of cardiac physiology, and mechanisms of initiation of arrhythmias and heart failure
Structural studies and drug discovery of serotonin receptors and transporters
Mechanisms that regulate chromatin structure and gene transcription
Structure and function of membrane transport proteins that play central roles in physiology and disease.
Translational studies on new drugs for osteoporosis, obesity and neurodegenerative diseases using cutting-edge technologies.
Structural mechanisms of epigenetic regulation of gene transcription in biology and human diseases, and structure-based drug discovery