Guidance and Policies

Policies define how the Icahn School of Medicine at Mount Sinai Program for the Protection of Human Subjects (PPHS) operates in the pursuit of human subjects' protection. Policies apply to all ISMMS research staff. Guidance is designed to assist the researcher and Institutional Review Board (IRB) member in understanding, interpreting, and applying the regulations and policies. Standard Operating Procedures describe the expectations for what and how a task should be accomplished.


Revised Common Rule: 

  • PPHS Announcement (11.28.19)
  • All new project submitted after January 21, 2019 are subject to the Revised Common Rule and should use the most recent version of the PPHS HRP-502 template (found on the Forms page, under For Researchers). Projects approved prior to 1/21/19 will remain under the old rule and should not transfer the consent documents to the new template. 

General Guidance:

National Institutes of Health

  • Certificates of Confidentiality (CoC) - Updates coming soon.
    • Contact the PPHS at if you have any questions.

Screening and Recruitment

Obtaining Consent

Future Use Data Sharing and Genetic Research

Data Security