Program for the Protection of Human Subjects

The Human Research Protection Program at the Icahn School of Medicine at Mount Sinai (ISMMS) is a comprehensive system to ensure the protection of the rights and welfare of subjects in human research. The Program for the Protection of Human Subjects (PPHS) is a key component of ISMMS’ efforts to ensure human subject protections. It supports our researchers in assuring the ethical conduct of research and compliance with federal, state, and institutional regulations, and provides a professional office staff to assist both investigators, participants, and five Institutional Review Boards (IRBs).

In addition, the overall Human Research Protection Program at ISMMS includes additional organizational, administrative, and investigator components, and is based on all individuals fulfilling their roles and responsibilities. Essential aspects of the overall mission of human subjects protection are provided by the organized interaction of the PPHS with the Financial Conflict of Interest Committee, the Clinical Trial Office, the Office of Research Compliance, the Biosafety Program, and the Radiation Safety Committee.

Our Human Research Protection Plan describes Mount Sinai’s plan to comply with ethical and legal requirements for the conduct and oversight of human research.

News and Announcements

January 9, 2020:

The new HRP-232 Form- Request to Rely will be mandatory for all new R2R submissions starting January 21, 2020. Submissions not including the new form will be rejected during intake review. The form can be located on the R2R page, under New Projects.

The PPHS has also released the following revised forms, which can be found on the Forms page:

  • HRP-212 Continuing/Final Review Progress Report (12/19/19)
  • HRP-224 Reportable New Information (12/12/19)

November 4, 2019:

The PPHS has released a new policy regarding the future use of data and/or specimens and a new guidance regarding the scanning of research files. Please visit the Guidance and Policies section of the website for more information.