Adult Leukemia Program

The Adult Leukemia Program at the Icahn School of Medicine at Mount Sinai is an internationally recognized comprehensive effort. It is dedicated to the clinical care of patients with acute and chronic leukemia, with a focus on the development of novel therapies for both forms. The program generates translational research to understand the underlying causes of leukemias and inform development of future therapeutics.

The clinical care team comprises an expert group of dedicated medical hematologist-oncologists, bone marrow transplant physicians, hematopathologists, oncology pharmacists, nurse practitioners, physician assistants, nurses, social workers, and medical assistants. The whole team is dedicated to delivering quality and compassionate care. In addition, the care team includes specialists from The Mount Sinai Hospital. We work closely with experts in infectious disease, pulmonary and critical care, nephrology, cardiology, gastroenterology, interventional radiology, and palliative care.

In addition to clinical care, the Adult Leukemia Program is dedicated to understanding the biologic basis of leukemia. Our goal is to develop novel therapies that improve patient outcomes. Through extensive collaboration with laboratory researchers, we have built a research infrastructure that brings findings from the laboratory directly to the clinic. Patients have access to many state-of-the-art clinical trials (see below). Our research addresses targeted therapies, novel antibodies, bispecific T-cell engagers, and hematopoietic stem cell products.

The Mount Sinai Hematology/Medical Oncology Fellowship Program is dedicated to the training, mentoring and career development of superb clinicians, outstanding critical thinkers and future academic leaders in Hematology and Medical Oncology. The fellowship includes 18 months of dedicated and protected research time in addition to clinical time, which includes rotations on the inpatient Leukemia service.  The opportunity to attend any of the Leukemia outpatient centers and engage in clinical and laboratory research with a focus in myeloid and lymphoid leukemia is available to all trainees.

Read more about the fellowship program here.

Prior Leukemia Fellows

Name Current Appointment
Bridget Marcellino  Assistant Professor of Medicine (Hematology and Medical Oncology), Icahn School of Medicine at Mount Sinai
 Sangeetha Venugopal  Leukemia Fellow, MD Anderson Cancer Center
 Daniel Aruch  Virginia Oncology Associates

Meet Our Director

John Mascarenhas, MD, is Director of the Adult Leukemia Program and Director of the Adult Blood Cancers and Myeloid Disorders Center of Excellence at the Mount Sinai Health System. He has extensive experience in clinical and translational research in chronic myeloid leukemias and the transition to acute leukemia. He has led numerous investigator-initiated and industry-sponsored clinical trials in myeloproliferative neoplasms and acute leukemia. He has presented nationally and internationally as an invited speaker on the topic of the biology and treatment of myeloid neoplasms and has served as an author of more than 150 publications, and over 12 book chapters. Additionally, he is a National Cancer Institute-funded Principal Investigator of the clinical trials project within the P01 grant supported Myeloproliferative Neoplasms Research Consortium.