Abilities Research

Our abilities researchers are focusing on three main areas of research: health and rehabilitation interventions for neurological disorders, bionics and technology, and performance enhancement. In the area of neurological disorders, we are working to develop novel rehabilitation therapies, preventative and disease-modifying treatments, and to better understand the mechanisms of motor dysfunction and recovery. Our bionics and technology research involves evaluating and refining cutting-edge robotics, neuromodulation techniques, mobile applications, and artificial intelligence to assist patients in achieving increased function and independence. Finally, the performance enhancement research aims to maximize athletic performance for both able-bodied and para-athletes through the development of pharmacological and electrophysiological procedures, as well as the use of wearables and multimodal assessments of body movement.

Spinal Cord Injury Research

We are at the forefront of research addressing the challenges faced by individuals with traumatic spinal cord injury (SCI). Our research spans a wide range of areas, from translational stem cell research to advanced technologies and robotics designed to facilitate walking and community integration.

Our investigators have been involved in groundbreaking research, including the use of biologic therapies such as implanting neutrophils and stem cells into the spinal cord, and participating in the first randomized controlled multi-center trial investigating the safety and effectiveness of transplanting neural stem cells into the spinal cord of individuals with chronic cervical SCI. Additionally, our team of physician scientists have been instrumental in developing and validating an international consensus classification of pain after SCI, which has become the current standard for classifying pain throughout the world. We are also testing novel ways of treating pain after SCI, as pain is a significant problem for the majority of persons with spinal cord injuries, and there are few effective therapies currently available. Another exciting area of research focuses on testing the usability of robotic-powered exoskeletons, which have been demonstrated to be usable by persons with higher levels of cervical injury for the first time.

Traumatic Brain Injury Research

Researchers at the Department of Rehabilitation and Human Performance are conducting groundbreaking research on traumatic brain injury (TBI), focusing on understanding the long-term effects and developing effective interventions for individuals living with the consequences of TBI. We are leading a longitudinal study and brain donor program to identify clinical signatures of post-traumatic neurodegeneration and facilitate early diagnosis and treatment. We also conduct research on TBI in military service members and veterans, intimate partner violence-related brain injury, emotion dysregulation after TBI, and the effects of COVID-19 on brain health. By identifying risk factors, biomarkers, and effective interventions, our research can lead to personalized treatment plans, improved long-term outcomes, and better quality of life for those affected by TBI.