Hematology and Coagulation

The Hematology and Coagulation Laboratory performs a wide range of routine and special hematology and coagulation testing. It serves The Mount Sinai Hospital, a 1,171 bed teaching hospital, including the Ruttenberg Cancer Center, as well as extensive outpatient and community outreach programs.

We work closely with other laboratories within the Mount Sinai Health System (including Flow Cytometry, Molecular Diagnostics, and Tumor Cytogenetics) to deliver comprehensive care in diagnosis and therapy.

The mission of the Hematology Laboratory is to:

  • Provide state-of-the-art testing for diagnosis and treatment
  • Develop novel technologies for clinical and research applications
  • Test diagnostic and prognostic disease markers that affect tailored therapy in support of our commitment to personalized medicine
  • Maintain patient care and safety
  • Preserve the highest levels of teaching excellence

Extensive Experience

The Hematology Laboratory has extensive experience in routine clinical testing, special hematology and coagulation testing, assay development, validation, implementation and quality control standards, methods, and compliance. We operate under a permit issued by the New York State Department of Health, and is accredited by the College of American Pathologists and the Joint Commission on Accreditation of Healthcare Organizations. We are also designated as a Hemoglobinopahty Specialty Center approved by the New York State Department of Health, Wadswoth Center.

Center Newborn Screening/Children with Special Health Care Needs Program

We use modern robotics and advanced technology in laboratory medicine. Our staff consists of a board certified physician and 48 licensed technologists and supervisors performing more than two million special hematology, special coagulation, as well as ‘routine’ tests each year. This flagship robotics laboratory, the largest in New York, operates 24 hours a day, seven days a week, providing some of the fastest possible turnaround times for stat, urgent, and routine specimen testing.

Hematology and Coagulation Clinical Services 

We report an average of 170,000 test results per month. Approximately 60 percent are automated test results (complete blood count (CBC), differential, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, urinalysis, and hemoglobin fractionation). We derive the remaining results from manual tests including erythrocyte sedimentation rate, sickle cell testing, erythrocyte G6PD evaluation, and a comprehensive array of specialty coagulation tests such as heparin monitoring by anti-Xa analysis, and tests for coagulation factor analysis and hypercoagulability.

We conduct a number of types of tests including the following: (To learn more, refer to the Test Information Library (must be connected to the Mount Sinai intranet). 

Routine Testing 

CBC, platelets and differential, aPTT, PT, fibrinogen cerebrospinal fluid (CSF) cell count and differential, manual differentiethrocyte sedimentation rate, fibrinogen, D-dimer, fluids, and urinalysis.

STAT Testing 

APTT, PT, CBC, CBC and platelets, CBC, platelets and differential, CSF cell count and differential, urine (chemical). (Per request, results typically available within one hour)

Special Hematology Testing 

High-performance liquid chromatography analysis supplemented by gel electrophoresis for the detection of abnormal hemoglobins, identification of sickle cell disease, identification of thalassemia and other hemoglobinopathies. 

Special Coagulation Laboratory 

Laboratory identification of coagulopathies and hypercoagulability conditions including:

  • Heparin-induced thrombocytopenia 
  • Hemophilia testing 
  • Factor deficiencies 
  • Factor inhibitors 
  • Von Willebrand’s disease 
  • Lupus anticoagulants 
  • Protein C and S deficiencies
  • Anti-thrombin III 
  • Anti Xa levels 
  • PFA-100 
  • Platelet aggregation testing: By appointment, scheduled in advance with the Coagulation Laboratory, Tel: 212-659-8141.

Francine R. Dembitzer, MD

Amy Duffield, MD, PhD

Bruce Petersen, MD

Ghia Junio BSMT, MBA
Chief Supervisor

Miriam Perekalsky
Hematology Supervisor, Special Hematology

David Brown
Hematology Supervisor, Core Laboratory

Glen Estavillo
Hematology Supervisor (evening)

Jun Mendajar
Hematology Supervisor (night)