Our laboratory provides state-of-the-art services in the detection of acquired chromosomal abnormalities associated with hematological malignancies and solid tumors. We offer all available cytogenetic techniques to identify the type and nature of complex structural abnormalities present in malignant (cancerous) cells. In addition to conventional cytogenetic analysis, we also provide fluorescence in situ hybridization (FISH) testing using disease-specific panels supported by an extensive FISH probe library, and a high resolution comparative genomic hybridization + single nucleotide polymorphisms (aCGH+SNP) array for detection of loss, gain, and copy number neutral - loss of heterozygosity (CN-LOH) in cancer related genes.
We offer a full range of services for clinicians and researchers from Mount Sinai and beyond, including the following assays:
- Cell culture
- Routine G-banded chromosome analysis
- Interphase, metaphase and multicolor FISH studies (using more than 100 FISH probes)
- Array CGH (comparative genomic hybridization)+ single nucleotide polymorphisms (SNPs), Agilent Cancer Platform