Internal Medicine Research

The Division of General Internal Medicine faculty has over 50 active research studies across a broad range of patient and population-based research activities spanning the hospital, ambulatory care, and home care settings. Methodological areas of focus include: clinical epidemiology, outcomes research, health services research, quality of care, health disparities, doctor-patient communication, chronic disease management, health beliefs, patient safety, medical errors, prediction rules, evidence-based medicine, medical education, and medical informatics. Specific topics include: asthma, hepatitis C, thromboembolic disease, cardiovascular disease, cerebrovascular disease, diabetes, hypertension, depression, pneumonia, homebound elderly, carotid endarterectomy, tuberculosis, lung cancer, colorectal cancer, women's health, palliative care, geriatrics, and medical education, among others.

Mount Sinai is committed to population health and the Healthfirst Quality Improvement Program is being led by Drs. Roy Cohen and Naabia Casely-Hayford at Mount Sinai St. Luke’s, John Andrilli and Desiree Chow at Mount Sinai Beth Israel, and Eva Waite, Aparna Sarin, and Jonathan Arend at Mount Sinai. Mount Sinai St. Luke’s and West scored first amongst over 30 practices on Medicare performance in 2012, third in Medicaid performance, most improved overall, and first in patient satisfaction. The experience has helped prepare the division for future Quality Pay for Performance programs through other payers, including the Mount Sinai ACO program and commercial insurance carriers.

See the list of grants for the Division of General Internal Medicine here.

Juan P. Wisnivesky, MD, DrPH
Dr. Wisnivesky is Chief of the Division of General Internal Medicine at the Icahn School of Medicine at Mount Sinai. He is a pulmonologist, clinical epidemiologist, and biostatistician whose research focuses on asthma, cancer epidemiology, and outcomes research. He has led several studies assessing the self-management, treatment, and outcomes for patients with asthma, COPD, multimorbidity, and lung cancer. He is also an expert in secondary analyses of national databases with a particular focus on cancer research, having published several manuscripts using the Surveillance, Epidemiology and End Results (SEER) and SEER-Medicare registries to conduct comparative effectiveness studies of diagnostic tests and treatments for lung cancer, as well as studies examining disparities in treatments and outcomes for cancer patients who differ by age, gender, or race. Please visit the Wisnivesky Laboratory.

Alex Federman, MD, MPH
Dr. Federman is Director of Research for the Division of General Internal Medicine, a primary care physician and health services researcher. He completed research training in the Harvard Medical School Faculty Development Program in General Internal Medicine. His research addresses self-management behaviors among older adults with complex chronic illnesses. This work encompasses themes such as health literacy, cognitive function, and illness and medication beliefs. His research also involves evaluation of innovative models of healthcare delivery in ambulatory and acute care settings. Please visit the Federman Laboratory.

Jennifer Jao, MD, MPH
Dual-certified in internal medicine and pediatrics, Dr. Jao is an infectious disease specialist with a clinical and research emphasis on HIV maternal child health. She is currently studying the metabolic effects of HIV and antiretrovirals on HIV-infected pregnant women and their children in both the U.S. and sub-Saharan Africa.

Minal Kale, MD, MPH
Dr. Kale is a primary care clinician and health services researcher with a strong interest in improving the delivery of cancer prevention and detection services for high-risk patients. She trained in internal medicine at New York University, and completed a fellowship in general internal medicine at the Icahn School of Medicine at Mount Sinai. She is currently funded by the National Cancer Institute to study the delivery of lung cancer screening to individuals with chronic obstructive pulmonary disease.

Joseph Kannry, MD
Dr. Kannry is a board certified clinical informaticist and a graduate of the Yale Center for Medical Informatics, a National Library of Medicine training program in informatics. His research has focused on clinical decision support, usability, integration of genomic clinical decision support into the electronic health record, leveraging electronic health records to support research, patient engagement with personal health records, and operationalizing informatics.

Jenny Lin, MD, MPH
Dr. Lin received her medical degree from Harvard Medical School and completed an internal medicine residency in the primary care track at Beth Israel Deaconess Hospital in Boston.  She has been a clinician-educator at the residency and medical school levels and is currently a clinician-investigator with a National Cancer Institute K07 career development award.  Her research examines the interrelationship between comorbid illness and cancer survivorship, specifically assessing diabetes self-management in patients with recently-diagnosed cancer.

Keith Sigel, MD, MPH
Dr. Sigel completed medical school and received a Masters Degree in Public Health at the University of North Carolina. He then completed residency training in internal medicine at Mount Sinai, followed by fellowships in general internal medicine and infectious diseases. His research focus is assessing cancer risk and optimizing cancer treatment in HIV infected persons. He is the principal investigator of a National Cancer Instituted-funded trial of lung cancer screening with computed tomography for HIV-infected smokers.

Jeffrey Weiss, PhD, MS
Dr. Weiss is a licensed clinical psychologist who has worked for over 23 years in the United States and Europe providing direct care to persons with HIV and hepatitis C virus infection and conducting research on how behavioral interventions can improve their quality and length of life. He developed the Psychosocial Readiness Assessment and Preparation for hepatitis C (PrepC; and co-developed the HepCure toolkit (

Faculty in the Division of General Internal Medicine (DGIM) conducting research studies are well-supported by the Division’s exceptional Research Program. The Research Program provides investigators and faculty interested in research collaborations with grant submission/management support, guidance on study implementation, audit preparation, and statistical analysis. Our team of over 30 trained research staff (3 data analyst, 8 project managers, and approximately 25 research coordinators) are knowledgeable in research methods and data collection. Approximately half of the staff is bilingual in Spanish, affording an underserved population of patients the opportunity to participate in research and ensuring our projects report on outcomes for the diverse New York City communities we serve.  Data analysts and project managers are available for consultation to Division faculty by contacting the Clinical Research Manager (Melissa Martynenko,

The Division of General Internal Medicine in the Department of Medicine at Icahn School of Medicine offers a two-year fellowship designed to prepare clinicians for careers in clinical and health services research.

The training curriculum includes coursework towards the completion of a degree in Masters of Public Health or Masters in Clinical Research, research or medical education seminars, mentored research projects, teaching, and patient care activities. Fellows work alongside research and education faculty within our Division and established investigators in other divisions and departments at Mount Sinai. Areas of research expertise in our Division include: health disparities, chronic disease self-management, primary care of aging populations, health care for homebound adults, comparative effectiveness research, and health policy, often in the context of asthma, cancer, diabetes, hypertension, HIV or hepatitis C. We collaborate extensively across departments at Mount Sinai enabling research and mentorship in many other disciplines as well.

A strength of the program is the breadth and depth of research interests held by the many established researchers at Mount Sinai and the tradition of collaboration across divisions and departments that creates abundant opportunities for mentored clinical research. With the support of faculty researchers, each fellow is expected to design, implement and complete multiple projects and present their findings through publication in peer-reviewed journals, abstract presentations, and talks at regional and national conferences.