Pediatric Research

The Department of Pediatrics at the Icahn School of Medicine at Mount Sinai has a long and distinguished tradition of excellence in clinical, translational, and basic research. Our research aims to better understand, treat, and prevent childhood diseases. Our Department is well-funded––both federally and non-federally. Our research portfolio continues to demonstrate in our extramural funding portfolio that exceeds $23 million.

Our Department’s research interests include:

  • Molecular genetics of congenital heart disease
  • Molecular physiology and regulation of ion transport in developing kidneys
  • Immune-pathogenic mechanisms and treatment of food allergy and asthma
  • Genetics and genomics of asthma and allergic diseases
  • Treatment and natural history of disorders relating to steroid biosynthesis
  • Regulation of chromatin structure and function during gene transcription
  • Molecular mechanisms underlying congenital disorders of glycosylation
  • Early life predictors of developmental diseases
  • Traumatic stress reactions and nonadherence to medical regimens
  • Modifiable causes of adverse outcomes in preterm and low-birthweight neonates
  • HPV persistence and risk factors among adolescent girls
  • Social determinants of health
  • Tobacco and marijuana smoke exposure and their impact on children
  • Genetics and immune responses in clinical presentations, treatment responses, and prognosis in inflammatory bowel disease (IBD)
  • Biomarkers and patient-related outcomes in juvenile idiopathic arthritis
  • Interventions to help teens at risk for type 2 diabetes

Mindich Child Health and Development Institute

The Mindich Child Health and Development Institute (MCHDI) is a translational research enterprise, which seeks to improve the knowledge base and therapies for pediatric diseases. Our research focuses on asthma and allergies, obesity and diabetes, cardiovascular disease, neurodevelopmental disorders, and more.

MCHDI provides an intellectually rich and supportive environment for fostering collaborative scientific investigation and Mount Sinai’s “bench to bedside” philosophy, as well as training the next generation of scientific leaders in child health research.